- Treatment resistant hypertension
- Endothelial and Vessel Function
- Type 2 Diabetes
- Interventional Therapy of Hypertension
The clinical research program focusses on pathogenetic mechanisms of target organ damage in arterial hypertension. The focus is on humoral, neural, genetic and inflammatory pathways, which are responsible for the high-pressure damage to vessels, kidneys, heart and brain. In treatment resistant hypertension, interventional techniques, such as renal denervation are analyzed for their efficacy and safety in the context of multicenter studies.
The clinical research group CRC, which location is in Nürnberg and Erlangen, conducts patient related studies with highly specialized technical, pharmacological and pathophysiological investigations. As part of further research projects endothelial and vascular function in the kidney, the forearm and eye with invasive and non-invasive measurements. According to the motto "The man is as old as its vessels", early structural and functional vascular abnormalities are investigated. This includes studies on the pathogenesis of albuminuria, whose importance as a vascular marker and therapeutic studies to reduce albuminuria. Investigator Initiated Trials (IIT) for the indication of hypertension, type 2 diabetes, cardiovascular and renal protection are also located.