Prof. Dr. Kai-Uwe Eckardt

Publikationsliste Prof. Dr. Kai-Uwe Eckardt

Steinbrenner I, Sekula P, Kotsis F, von Cube M, Cheng Y, Nadal J, Schmid M, Schneider MP, Krane V, Nauck M, Eckardt KU, Schultheiss UT, GCKD investigators , Eckardt KU, Meiselbach H, Schneider MP, Schiffer M, Prokosch HU, Bärthlein B, Beck A, Reis A, Ekici AB, Becker S, Becker-Grosspitsch D, Alberth-Schmidt U, Hausknecht B, Weigel A, Walz G, Köttgen A, Schultheiß UT, Kotsis F, Meder S, Mitsch E, Reinhard U, Floege J, Saritas T, Schaeffner E, Baid-Agrawal S, Theisen K, Haller H, Menne J, Zeier M, Sommerer C, Theilinger J, Wolf G, Busch M, Paul R, Sitter T, Wanner C, Krane V, Börner-Klein A, Bauer B, Kronenberg F, Raschenberger J, Kollerits B, Forer L, Schönherr S, Weissensteiner H, Oefner P, Gronwald W, Schmid M, Nadal J: (2023) Association of osteopontin with kidney function and kidney failure in chronic kidney disease patients: the GCKD study. Nephrol Dial Transplant. 2023;38(6): 1430-1438
Bächle H, Sekula P, Schlosser P, Steinbrenner I, Cheng Y, Kotsis F, Meiselbach H, Stockmann H, Schönherr S, GCKD investigators , Eckardt KU, Devuyst O, Scherberich J, Köttgen A, Schultheiss UT: (2023) Uromodulin and its association with urinary metabolites: the German Chronic Kidney Disease Study. Nephrol Dial Transplant. 2023;38(1): 70-79
Mielke J, Trucks-Jansen H, Schurmann C, Kotsis F, Köttgen A, Schneider MP, Eckardt KU, GCKD Investigators , Freitag DF, Eitner F, Becker MS, Kotsis F, Köttgen A, Schneider MP, Eckardt KU: (2023) Prevalence, phenotypic characteristics and prognostic role of apparent treatment resistant hypertension in the German Chronic Kidney Disease (GCKD) study. J Hum Hypertens. 2023;37(5): 345-353
Matsushita K, Kaptoge S, Hageman SHJ, Sang Y, Ballew SH, Grams ME, Surapaneni A, Sun L, Arnlov J, Bozic M, Brenner H, Brunskill NJ, Chang AR, Chinnadurai R, Cirillo M, Correa A, Ebert N, Eckardt KU, Gansevoort RT, Gutierrez O, Hadaegh F, He J, Hwang SJ, Jafar TH, Jassal SK, Kayama T, Kovesdy CP, Landman GW, Levey AS, Lloyd-Jones DM, Major RW, Miura K, Muntner P, Nadkarni GN, Nowak C, Ohkubo T, Pena MJ, Polkinghorne KR, Sairenchi T, Schaeffner E, Schneider MP, Shalev V, Shlipak MG, Solbu MD, Stempniewicz N, Tollitt J, Valdivielso JM, van der Leeuw J, Wang AY, Wen CP, Woodward M, Yamagishi K, Yatsuya H, Zhang L, Dorresteijn JAN, Di Angelantonio E, Visseren FLJ, Pennells L, Coresh J: (2023) Including measures of chronic kidney disease to improve cardiovascular risk prediction by SCORE2 and SCORE2-OP. Eur J Prev Cardiol. 2023;30(1): 8-16
Steinbrenner I, Yu Z, Jin J, Schultheiss UT, Kotsis F, Grams ME, Coresh J, Wuttke M, GCKD Investigators , Kronenberg F, Eckardt KU, Chatterjee N, Sekula P, Köttgen A: (2023) A polygenic score for reduced kidney function and adverse outcomes in a cohort with chronic kidney disease. Kidney Int. 2023;103(2): 421-424
Schachtl-Riess JF, Schönherr S, Lamina C, Forer L, Coassin S, Streiter G, Kheirkhah A, Li Y, Meiselbach H, Di Maio S, Eckardt KU, Köttgen A, Kronenberg F, GCKD investigators: (2023) KLKB1 and CLSTN2 are associated with HDL-mediated cholesterol efflux capacity in a genome-wide association study. Atherosclerosis. 2023;368(): 1-11
Pfau A, López-Cayuqueo KI, Scherer N, Wuttke M, Wernstedt A, González Fassrainer D, Smith DE, van de Kamp JM, Ziegeler K, Eckardt KU, Luft FC, Aronson PS, Köttgen A, Jentsch TJ, Knauf F: (2023) SLC26A1 is a major determinant of sulfate homeostasis in humans. J Clin Invest. 2023;133(3):
Ostendorf L, Burns M, Wagner DL, Enghard P, Amann K, Mei H, Eckardt KU, Seelow E, Schreiber A: (2023) Daratumumab for the treatment of refractory ANCA-associated vasculitis. RMD Open. 2023;9(1):
Zacharias HU, Altenbuchinger M, Schultheiss UT, Raffler J, Kotsis F, Ghasemi S, Ali I, Kollerits B, Metzger M, Steinbrenner I, Sekula P, Massy ZA, Combe C, Kalra PA, Kronenberg F, Stengel B, Eckardt KU, Köttgen A, Schmid M, Gronwald W, Oefner PJ, GCKD Investigators: (2022) A Predictive Model for Progression of CKD to Kidney Failure Based on Routine Laboratory Tests. Am J Kidney Dis. 2022;79(2): 217-230.e1
Winkler TW, Rasheed H, Teumer A, Gorski M, Rowan BX, Stanzick KJ, Thomas LF, Tin A, Hoppmann A, Chu AY, Tayo B, Thio CHL, Cusi D, Chai JF, Sieber KB, Horn K, Li M, Scholz M, Cocca M, Wuttke M, van der Most PJ, Yang Q, Ghasemi S, Nutile T, Li Y, Pontali G, Günther F, Dehghan A, Correa A, Parsa A, Feresin A, de Vries APJ, Zonderman AB, Smith AV, Oldehinkel AJ, De Grandi A, Rosenkranz AR, Franke A, Teren A, Metspalu A, Hicks AA, Morris AP, Tönjes A, Morgan A, Podgornaia AI, Peters A, Körner A, Mahajan A, Campbell A, Freedman BI, Spedicati B, Ponte B, Schöttker B, Brumpton B, Banas B, Krämer BK, Jung B, Åsvold BO, Smith BH, Ning B, Penninx BWJH, Vanderwerff BR, Psaty BM, Kammerer CM, Langefeld CD, Hayward C, Spracklen CN, Robinson-Cohen C, Hartman CA, Lindgren CM, Wang C, Sabanayagam C, Heng CK, Lanzani C, Khor CC, Cheng CY, Fuchsberger C, Gieger C, Shaffer CM, Schulz CA, Willer CJ, Chasman DI, Gudbjartsson DF, Ruggiero D, Toniolo D, Czamara D, Porteous DJ, Waterworth DM, Mascalzoni D, Mook-Kanamori DO, Reilly DF, Daw EW, Hofer E, Boerwinkle E, Salvi E, Bottinger EP, Tai ES, Catamo E, Rizzi F, Guo F, Rivadeneira F, Guilianini F, Sveinbjornsson G, Ehret G, Waeber G, Biino G, Girotto G, Pistis G, Nadkarni GN, Delgado GE, Montgomery GW, Snieder H, Campbell H, White HD, Gao H, Stringham HM, Schmidt H, Li H, Brenner H, Holm H, Kirsten H, Kramer H, Rudan I, Nolte IM, Tzoulaki I, Olafsson I, Martins J, Cook JP, Wilson JF, Halbritter J, Felix JF, Divers J, Kooner JS, Lee JJ, O'Connell J, Rotter JI, Liu J, Xu J, Thiery J, Ärnlöv J, Kuusisto J, Jakobsdottir J, Tremblay J, Chambers JC, Whitfield JB, Gaziano JM, Marten J, Coresh J, Jonas JB, Mychaleckyj JC, Christensen K, Eckardt KU, Mohlke KL, Endlich K, Dittrich K, Ryan KA, Rice KM, Taylor KD, Ho K, Nikus K, Matsuda K, Strauch K, Miliku K, Hveem K, Lind L, Wallentin L, Yerges-Armstrong LM, Raffield LM, Phillips LS, Launer LJ, Lyytikäinen LP, Lange LA, Citterio L, Klaric L, Ikram MA, Ising M, Kleber ME, Francescatto M, Concas MP, Ciullo M, Piratsu M, Orho-Melander M, Laakso M, Loeffler M, Perola M, de Borst MH, Gögele M, Bianca M, Lukas MA, Feitosa MF, Biggs ML, Wojczynski MK, Kavousi M, Kanai M, Akiyama M, Yasuda M, Nauck M, Waldenberger M, Chee ML, Chee ML, Boehnke M, Preuss MH, Stumvoll M, Province MA, Evans MK, O'Donoghue ML, Kubo M, Kähönen M, Kastarinen M, Nalls MA, Kuokkanen M, Ghanbari M, Bochud M, Josyula NS, Martin NG, Tan NYQ, Palmer ND, Pirastu N, Schupf N, Verweij N, Hutri-Kähönen N, Mononen N, Bansal N, Devuyst O, Melander O, Raitakari OT, Polasek O, Manunta P, Gasparini P, Mishra PP, Sulem P, Magnusson PKE, Elliott P, Ridker PM, Hamet P, Svensson PO, Joshi PK, Kovacs P, Pramstaller PP, Rossing P, Vollenweider P, van der Harst P, Dorajoo R, Sim RZH, Burkhardt R, Tao R, Noordam R, Mägi R, Schmidt R, de Mutsert R, Rueedi R, van Dam RM, Carroll RJ, Gansevoort RT, Loos RJF, Felicita SC, Sedaghat S, Padmanabhan S, Freitag-Wolf S, Pendergrass SA, Graham SE, Gordon SD, Hwang SJ, Kerr SM, Vaccargiu S, Patil SB, Hallan S, Bakker SJL, Lim SC, Lucae S, Vogelezang S, Bergmann S, Corre T, Ahluwalia TS, Lehtimäki T, Boutin TS, Meitinger T, Wong TY, Bergler T, Rabelink TJ, Esko T, Haller T, Thorsteinsdottir U, Völker U, Foo VHX, Salomaa V, Vitart V, Giedraitis V, Gudnason V, Jaddoe VWV, Huang W, Zhang W, Wei WB, Kiess W, März W, Koenig W, Lieb W, Gao X, Sim X, Wang YX, Friedlander Y, Tham YC, Kamatani Y, Okada Y, Milaneschi Y, Yu Z, Lifelines cohort study , DiscovEHR/MyCode study , VA Million Veteran Program , Stark KJ, Stefansson K, Böger CA, Hung AM, Kronenberg F, Köttgen A, Pattaro C, Heid IM, Thio CHL, van der Most PJ, de Borst MH, Ho K, Josyula NS, Pendergrass SA, Rowan BX, Robinson-Cohen C, Gaziano JM, Phillips LS, Tao R, Hung AM: (2022) Differential and shared genetic effects on kidney function between diabetic and non-diabetic individuals. Commun Biol. 2022;5(1):
Mahajan A, Spracklen CN, Zhang W, Ng MCY, Petty LE, Kitajima H, Yu GZ, Rüeger S, Speidel L, Kim YJ, Horikoshi M, Mercader JM, Taliun D, Moon S, Kwak SH, Robertson NR, Rayner NW, Loh M, Kim BJ, Chiou J, Miguel-Escalada I, Della Briotta Parolo P, Lin K, Bragg F, Preuss MH, Takeuchi F, Nano J, Guo X, Lamri A, Nakatochi M, Scott RA, Lee JJ, Huerta-Chagoya A, Graff M, Chai JF, Parra EJ, Yao J, Bielak LF, Tabara Y, Hai Y, Steinthorsdottir V, Cook JP, Kals M, Grarup N, Schmidt EM, Pan I, Sofer T, Wuttke M, Sarnowski C, Gieger C, Nousome D, Trompet S, Long J, Sun M, Tong L, Chen WM, Ahmad M, Noordam R, Lim VJY, Tam CHT, Joo YY, Chen CH, Raffield LM, Lecoeur C, Prins BP, Nicolas A, Yanek LR, Chen G, Jensen RA, Tajuddin S, Kabagambe EK, An P, Xiang AH, Choi HS, Cade BE, Tan J, Flanagan J, Abaitua F, Adair LS, Adeyemo A, Aguilar-Salinas CA, Akiyama M, Anand SS, Bertoni A, Bian Z, Bork-Jensen J, Brandslund I, Brody JA, Brummett CM, Buchanan TA, Canouil M, Chan JCN, Chang LC, Chee ML, Chen J, Chen SH, Chen YT, Chen Z, Chuang LM, Cushman M, Das SK, de Silva HJ, Dedoussis G, Dimitrov L, Doumatey AP, Du S, Duan Q, Eckardt KU, Emery LS, Evans DS, Evans MK, Fischer K, Floyd JS, Ford I, Fornage M, Franco OH, Frayling TM, Freedman BI, Fuchsberger C, Genter P, Gerstein HC, Giedraitis V, González-Villalpando C, González-Villalpando ME, Goodarzi MO, Gordon-Larsen P, Gorkin D, Gross M, Guo Y, Hackinger S, Han S, Hattersley AT, Herder C, Howard AG, Hsueh W, Huang M, Huang W, Hung YJ, Hwang MY, Hwu CM, Ichihara S, Ikram MA, Ingelsson M, Islam MT, Isono M, Jang HM, Jasmine F, Jiang G, Jonas JB, Jørgensen ME, Jørgensen T, Kamatani Y, Kandeel FR, Kasturiratne A, Katsuya T, Kaur V, Kawaguchi T, Keaton JM, Kho AN, Khor CC, Kibriya MG, Kim DH, Kohara K, Kriebel J, Kronenberg F, Kuusisto J, Läll K, Lange LA, Lee MS, Lee NR, Leong A, Li L, Li Y, Li-Gao R, Ligthart S, Lindgren CM, Linneberg A, Liu CT, Liu J, Locke AE, Louie T, Luan J, Luk AO, Luo X, Lv J, Lyssenko V, Mamakou V, Mani KR, Meitinger T, Metspalu A, Morris AD, Nadkarni GN, Nadler JL, Nalls MA, Nayak U, Nongmaithem SS, Ntalla I, Okada Y, Orozco L, Patel SR, Pereira MA, Peters A, Pirie FJ, Porneala B, Prasad G, Preissl S, Rasmussen-Torvik LJ, Reiner AP, Roden M, Rohde R, Roll K, Sabanayagam C, Sander M, Sandow K, Sattar N, Schönherr S, Schurmann C, Shahriar M, Shi J, Shin DM, Shriner D, Smith JA, So WY, Stančáková A, Stilp AM, Strauch K, Suzuki K, Takahashi A, Taylor KD, Thorand B, Thorleifsson G, Thorsteinsdottir U, Tomlinson B, Torres JM, Tsai FJ, Tuomilehto J, Tusie-Luna T, Udler MS, Valladares-Salgado A, van Dam RM, van Klinken JB, Varma R, Vujkovic M, Wacher-Rodarte N, Wheeler E, Whitsel EA, Wickremasinghe AR, van Dijk KW, Witte DR, Yajnik CS, Yamamoto K, Yamauchi T, Yengo L, Yoon K, Yu C, Yuan JM, Yusuf S, Zhang L, Zheng W, FinnGen , eMERGE Consortium , Raffel LJ, Igase M, Ipp E, Redline S, Cho YS, Lind L, Province MA, Hanis CL, Peyser PA, Ingelsson E, Zonderman AB, Psaty BM, Wang YX, Rotimi CN, Becker DM, Matsuda F, Liu Y, Zeggini E, Yokota M, Rich SS, Kooperberg C, Pankow JS, Engert JC, Chen YI, Froguel P, Wilson JG, Sheu WHH, Kardia SLR, Wu JY, Hayes MG, Ma RCW, Wong TY, Groop L, Mook-Kanamori DO, Chandak GR, Collins FS, Bharadwaj D, Paré G, Sale MM, Ahsan H, Motala AA, Shu XO, Park KS, Jukema JW, Cruz M, McKean-Cowdin R, Grallert H, Cheng CY, Bottinger EP, Dehghan A, Tai ES, Dupuis J, Kato N, Laakso M, Köttgen A, Koh WP, Palmer CNA, Liu S, Abecasis G, Kooner JS, Loos RJF, North KE, Haiman CA, Florez JC, Saleheen D, Hansen T, Pedersen O, Mägi R, Langenberg C, Wareham NJ, Maeda S, Kadowaki T, Lee J, Millwood IY, Walters RG, Stefansson K, Myers SR, Ferrer J, Gaulton KJ, Meigs JB, Mohlke KL, Gloyn AL, Bowden DW, Below JE, Chambers JC, Sim X, Boehnke M, Rotter JI, McCarthy MI, Morris AP, Rüeger S, Della Briotta Parolo P, Joo YY, Hayes MG: (2022) Multi-ancestry genetic study of type 2 diabetes highlights the power of diverse populations for discovery and translation. Nat Genet. 2022;54(5): 560-572
Kheirkhah A, Lamina C, Kollerits B, Schachtl-Riess JF, Schultheiss UT, Forer L, Sekula P, Kotsis F, Eckardt KU, Kronenberg F, GCKD Investigators , Eckardt KU, Meiselbach H, Schneider MP, Schiffer M, Prokosch HU, Bärthlein B, Beck A, Reis A, Ekici AB, Becker S, Becker-Grosspitsch D, Alberth-Schmidt U, Hausknecht B, Weigel A, Walz G, Köttgen A, Schultheiß UT, Kotsis F, Meder S, Mitsch E, Reinhard U, Floege J, Saritas T, Schaeffner E, Baid-Agrawal S, Theisen K, Haller H, Menne J, Zeier M, Sommerer C, Theilinger J, Wolf G, Busch M, Paul R, Sitter T, Wanner C, Krane V, Börner-Klein A, Bauer B, Kronenberg F, Raschenberger J, Kollerits B, Forer L, Schönherr S, Weissensteiner H, Oefner P, Gronwald W, Schmid M, Nadal J: (2022) PCSK9 and Cardiovascular Disease in Individuals with Moderately Decreased Kidney Function. Clin J Am Soc Nephrol. 2022;17(6): 809-818
Li Y, Cheng Y, Consolato F, Schiano G, Chong MR, Pietzner M, Nguyen NQH, Scherer N, Biggs ML, Kleber ME, Haug S, Göçmen B, Pigeyre M, Sekula P, Steinbrenner I, Schlosser P, Joseph CB, Brody JA, Grams ME, Hayward C, Schultheiss UT, Krämer BK, Kronenberg F, Peters A, Seissler J, Steubl D, Then C, Wuttke M, März W, Eckardt KU, Gieger C, Boerwinkle E, Psaty BM, Coresh J, Oefner PJ, Pare G, Langenberg C, Scherberich JE, Yu B, Akilesh S, Devuyst O, Rampoldi L, Köttgen A: (2022) Genome-wide studies reveal factors associated with circulating uromodulin and its relationships to complex diseases. JCI Insight. 2022;7(10):
Cheng Y, Li Y, Scherer N, Grundner-Culemann F, Lehtimäki T, Mishra BH, Raitakari OT, Nauck M, Eckardt KU, Sekula P, Schultheiss UT, GCKD investigators: (2022) Genetics of osteopontin in patients with chronic kidney disease: The German Chronic Kidney Disease study. PLoS Genet. 2022;18(4):
Winitzki D, Zacharias HU, Nadal J, Baid-Agrawal S, Schaeffner E, Schmid M, Busch M, Bergmann MM, Schultheiss U, Kotsis F, Stockmann H, Meiselbach H, Wolf G, Krane V, Sommerer C, Eckardt KU, Schneider MP, Schlieper G, Floege J, Saritas T: (2022) Educational Attainment Is Associated With Kidney and Cardiovascular Outcomes in the German CKD (GCKD) Cohort. Kidney Int Rep. 2022;7(5): 1004-1015
Joseph CB, Mariniello M, Yoshifuji A, Schiano G, Lake J, Marten J, Richmond A, Huffman JE, Campbell A, Harris SE, Troyanov S, Cocca M, Robino A, Thériault S, Eckardt KU, Wuttke M, Cheng Y, Corre T, Kolcic I, Black C, Bruat V, Concas MP, Sala C, Aeschbacher S, Schaefer F, Bergmann S, Campbell H, Olden M, Polasek O, Porteous DJ, Deary IJ, Madore F, Awadalla P, Girotto G, Ulivi S, Conen D, Wuehl E, Olinger E, Wilson JF, Bochud M, Köttgen A, Hayward C, Devuyst O: (2022) Meta-GWAS Reveals Novel Genetic Variants Associated with Urinary Excretion of Uromodulin. J Am Soc Nephrol. 2022;33(3): 511-529
Schneider MP, Schmid M, Nadal J, Wanner C, Krane V, Floege J, Saritas T, Busch M, Sitter T, Friedrich N, Stockmann H, Meiselbach H, Nauck M, Kronenberg F, Eckardt KU, GCKD Study Investigators , Schiffer M, Prokosch HU, Bärthlein B, Beck A, Reis A, Ekici AB, Becker S, Becker-Grosspitsch D, Alberth-Schmidt U, Hausknecht B, Weigel A, Walz G, Köttgen A, Schultheiß UT, Kotsis F, Meder S, Mitsch E, Reinhard U, Schaeffner E, Baid-Agrawal S, Theisen K, Haller H, Menne J, Zeier M, Sommerer C, Theilinger J, Wolf G, Paul R, Börner-Klein A, Bauer B, Raschenberger J, Kollerits B, Forer L, Schönherr S, Weissensteiner H, Oefner P, Gronwald W: (2022) Heart-Type Fatty Acid Binding Protein, Cardiovascular Outcomes, and Death: Findings From the German CKD Cohort Study. Am J Kidney Dis. 2022;80(4): 483-494.e1
Gorski M, Rasheed H, Teumer A, Thomas LF, Graham SE, Sveinbjornsson G, Winkler TW, Günther F, Stark KJ, Chai JF, Tayo BO, Wuttke M, Li Y, Tin A, Ahluwalia TS, Ärnlöv J, Åsvold BO, Bakker SJL, Banas B, Bansal N, Biggs ML, Biino G, Böhnke M, Boerwinkle E, Bottinger EP, Brenner H, Brumpton B, Carroll RJ, Chaker L, Chalmers J, Chee ML, Chee ML, Cheng CY, Chu AY, Ciullo M, Cocca M, Cook JP, Coresh J, Cusi D, de Borst MH, Degenhardt F, Eckardt KU, Endlich K, Evans MK, Feitosa MF, Franke A, Freitag-Wolf S, Fuchsberger C, Gampawar P, Gansevoort RT, Ghanbari M, Ghasemi S, Giedraitis V, Gieger C, Gudbjartsson DF, Hallan S, Hamet P, Hishida A, Ho K, Hofer E, Holleczek B, Holm H, Hoppmann A, Horn K, Hutri-Kähönen N, Hveem K, Hwang SJ, Ikram MA, Josyula NS, Jung B, Kähönen M, Karabegović I, Khor CC, Koenig W, Kramer H, Krämer BK, Kühnel B, Kuusisto J, Laakso M, Lange LA, Lehtimäki T, Li M, Lieb W, Lifelines Cohort Study , Lind L, Lindgren CM, Loos RJF, Lukas MA, Lyytikäinen LP, Mahajan A, Matias-Garcia PR, Meisinger C, Meitinger T, Melander O, Milaneschi Y, Mishra PP, Mononen N, Morris AP, Mychaleckyj JC, Nadkarni GN, Naito M, Nakatochi M, Nalls MA, Nauck M, Nikus K, Ning B, Nolte IM, Nutile T, O'Donoghue ML, O'Connell J, Olafsson I, Orho-Melander M, Parsa A, Pendergrass SA, Penninx BWJH, Pirastu M, Preuss MH, Psaty BM, Raffield LM, Raitakari OT, Rheinberger M, Rice KM, Rizzi F, Rosenkranz AR, Rossing P, Rotter JI, Ruggiero D, Ryan KA, Sabanayagam C, Salvi E, Schmidt H, Schmidt R, Scholz M, Schöttker B, Schulz CA, Sedaghat S, Shaffer CM, Sieber KB, Sim X, Sims M, Snieder H, Stanzick KJ, Thorsteinsdottir U, Stocker H, Strauch K, Stringham HM, Sulem P, Szymczak S, Taylor KD, Thio CHL, Tremblay J, Vaccargiu S, van der Harst P, van der Most PJ, Verweij N, Völker U, Wakai K, Waldenberger M, Wallentin L, Wallner S, Wang J, Waterworth DM, White HD, Willer CJ, Wong TY, Woodward M, Yang Q, Yerges-Armstrong LM, Zimmermann M, Zonderman AB, Bergler T, Stefansson K, Böger CA, Pattaro C, Köttgen A, Kronenberg F, Heid IM: (2022) Genetic loci and prioritization of genes for kidney function decline derived from a meta-analysis of 62 longitudinal genome-wide association studies. Kidney Int. 2022;102(3): 624-639
Steinbrenner I, Yu Z, Jin J, Schultheiss UT, Kotsis FK, Grams M, Coresh J, Eckardt KU, Sekula P, Chatterjee N, Koettgen A: (2022) A POLYGENIC RISK SCORE FOR REDUCED EGFR IS ASSOCIATED WITH ADVERSE EVENTS IN A CHRONIC KIDNEY DISEASE COHORT - THE GERMAN CHRONIC KIDNEY DISEASE STUDY Nephrol Dial Transplant. 2022;37 Suppl 3(): I374-I375
Dziodzio T, Hillebrandt KH, Knitter S, Nösser M, Globke B, Ritschl PV, Biebl M, Denecke C, Raakow J, Lurje G, Schöning W, Schmelzle M, Kahl A, Fütterer M, Budde K, Eckardt KU, Halleck F, Pratschke J, Öllinger R, German Bariatric Surgery, Kidney Transplantation Group , Volker A, Anette B, Peter B, Adrian B, Felix B, Jens B, Aydin E, Susan F, Frank F, Andreas F, Josef G, Klaus G, Martina G, Wilfried G, Fabian H, Michael H, Uta H, Histros K, Michael K, Stephan K, Martina K, Markus K, Uwe K, Christine K, Sven L, Lutz L, Shanti L, Kai L, Steffen M, Christian M, Anja M, Silvio N, Martin N, Robert Ö, Mirian O, Ulrich P, Ursula P, Przemyslaw P, Juliane P, Thomas R, Peter S, Daniel S, Stefan S, Florian S, Michael S, Walter TJ, Julia WM, Peter W, Karl W, Daniel Z: (2022) Body Mass Index Thresholds and the Use of Bariatric Surgery in the Field of Kidney Transplantation in Germany. Obes Surg. 2022;32(5): 1641-1648
Olinger E, Schaeffer C, Kidd K, Elhassan EAE, Cheng Y, Dufour I, Schiano G, Mabillard H, Pasqualetto E, Hofmann P, Fuster DG, Kistler AD, Wilson IJ, Kmoch S, Raymond L, Robert T, Genomics England Research Consortium , Eckardt KU, Bleyer AJ, Köttgen A, Conlon PJ, Wiesener M, Sayer JA, Rampoldi L, Devuyst O: (2022) An intermediate-effect size variant in UMOD confers risk for chronic kidney disease. Proc Natl Acad Sci U S A. 2022;119(33):
Popp B, Ekici AB, Knaup KX, Schneider K, Uebe S, Park J, Bafna V, Meiselbach H, Eckardt KU, Schiffer M, Reis A, Kraus C, Wiesener M: (2022) Prevalence of hereditary tubulointerstitial kidney diseases in the German Chronic Kidney Disease study. Eur J Hum Genet. 2022;30(12): 1413-1422
Neri L, Lonati C, Titapiccolo JI, Nadal J, Meiselbach H, Schmid M, Baerthlein B, Tschulena U, Schneider MP, Schultheiss UT, Barbieri C, Moore C, Steppan S, Eckardt KU, Stuard S, Bellocchio F: (2022) The Cardiovascular Literature-Based Risk Algorithm (CALIBRA): Predicting Cardiovascular Events in Patients With Non-Dialysis Dependent Chronic Kidney Disease. Front Nephrol. 2022;2():
Schwaiger JP, Kollerits B, Steinbrenner I, Weissensteiner H, Schönherr S, Forer L, Kotsis F, Lamina C, Schneider MP, Schultheiss UT, Wanner C, Köttgen A, Eckardt KU, Kronenberg F, GCKD Investigators: (2022) Apolipoprotein A-IV concentrations and clinical outcomes in a large chronic kidney disease cohort: Results from the GCKD study. J Intern Med. 2022;291(5): 622-636
Fazzini F, Lamina C, Raftopoulou A, Koller A, Fuchsberger C, Pattaro C, Del Greco FM, Döttelmayer P, Fendt L, Fritz J, Meiselbach H, Schönherr S, Forer L, Weissensteiner H, Pramstaller PP, Eckardt KU, Hicks AA, Kronenberg F, GCKD Investigators , Eckardt KU, Meiselbach H, Schneider M, Schiffer M, Prokosch HU, Bärthlein B, Beck A, Kraska D, Reis A, Ekici AB, Becker S, Becker-Grosspitsch D, Alberth-Schmidt U, Hausknecht B, Weigel A, Walz G, Köttgen A, Schultheiß UT, Kotsis F, Meder S, Mitsch E, Reinhard U, Floege J, Saritas T, Schaeffner E, Baid-Agrawal S, Theisen K, Haller H, Menne J, Zeier M, Sommerer C, Theilinger J, Wolf G, Busch M, Paul R, Sitter T, Wanner C, Krane V, Börner-Klein A, Bauer B, Kronenberg F, Raschenberger J, Kollerits B, Forer L, Schönherr S, Weissensteiner H, Oefner P, Gronwald W, Schmid M, Nadal J: (2021) Association of mitochondrial DNA copy number with metabolic syndrome and type 2 diabetes in 14 176 individuals. J Intern Med. 2021;290(1): 190-202
Kielstein JT, Heisterkamp M, Jing J, Nadal J, Schmid M, Kronenberg F, Busch M, Sommerer C, Lorenzen JM, Eckardt KU, Köttgen A, GCKD Study Investigators: (2021) Spectrum and dosing of urate-lowering drugs in a large cohort of chronic kidney disease patients and their effect on serum urate levels: a cross-sectional analysis from the German Chronic Kidney Disease study. Clin Kidney J. 2021;14(1): 277-283
Gorski M, Jung B, Li Y, Matias-Garcia PR, Wuttke M, Coassin S, Thio CHL, Kleber ME, Winkler TW, Wanner V, Chai JF, Chu AY, Cocca M, Feitosa MF, Ghasemi S, Hoppmann A, Horn K, Li M, Nutile T, Scholz M, Sieber KB, Teumer A, Tin A, Wang J, Tayo BO, Ahluwalia TS, Almgren P, Bakker SJL, Banas B, Bansal N, Biggs ML, Boerwinkle E, Bottinger EP, Brenner H, Carroll RJ, Chalmers J, Chee ML, Chee ML, Cheng CY, Coresh J, de Borst MH, Degenhardt F, Eckardt KU, Endlich K, Franke A, Freitag-Wolf S, Gampawar P, Gansevoort RT, Ghanbari M, Gieger C, Hamet P, Ho K, Hofer E, Holleczek B, Xian Foo VH, Hutri-Kähönen N, Hwang SJ, Ikram MA, Josyula NS, Kähönen M, Khor CC, Koenig W, Kramer H, Krämer BK, Kühnel B, Lange LA, Lehtimäki T, Lieb W, Lifelines cohort study , Regeneron Genetics Center , Loos RJF, Lukas MA, Lyytikäinen LP, Meisinger C, Meitinger T, Melander O, Milaneschi Y, Mishra PP, Mononen N, Mychaleckyj JC, Nadkarni GN, Nauck M, Nikus K, Ning B, Nolte IM, O'Donoghue ML, Orho-Melander M, Pendergrass SA, Penninx BWJH, Preuss MH, Psaty BM, Raffield LM, Raitakari OT, Rettig R, Rheinberger M, Rice KM, Rosenkranz AR, Rossing P, Rotter JI, Sabanayagam C, Schmidt H, Schmidt R, Schöttker B, Schulz CA, Sedaghat S, Shaffer CM, Strauch K, Szymczak S, Taylor KD, Tremblay J, Chaker L, van der Harst P, van der Most PJ, Verweij N, Völker U, Waldenberger M, Wallentin L, Waterworth DM, White HD, Wilson JG, Wong TY, Woodward M, Yang Q, Yasuda M, Yerges-Armstrong LM, Zhang Y, Snieder H, Wanner C, Böger CA, Köttgen A, Kronenberg F, Pattaro C, Heid IM: (2021) Meta-analysis uncovers genome-wide significant variants for rapid kidney function decline. Kidney Int. 2021;99(4): 926-939
Kaesler N, Baid-Agrawal S, Grams S, Nadal J, Schmid M, Schneider MP, Eckardt KU, Floege J, Bergmann MM, Schlieper G, Saritas T: (2021) Low adherence to CKD-specific dietary recommendations associates with impaired kidney function, dyslipidemia, and inflammation. Eur J Clin Nutr. 2021;75(9): 1389-1397
Alesutan I, Luong TTD, Schelski N, Masyout J, Hille S, Schneider MP, Graham D, Zickler D, Verheyen N, Estepa M, Pasch A, Maerz W, Tomaschitz A, Pilz S, Frey N, Lang F, Delles C, Müller OJ, Pieske B, Eckardt KU, Scherberich J, Voelkl J: (2021) Circulating uromodulin inhibits vascular calcification by interfering with pro-inflammatory cytokine signalling. Cardiovasc Res. 2021;117(3): 930-941
Cheng Y, Schlosser P, Hertel J, Sekula P, Oefner PJ, Spiekerkoetter U, Mielke J, Freitag DF, Schmidts M, GCKD Investigators , Kronenberg F, Eckardt KU, Thiele I, Li Y, Köttgen A, Oefner PJ, Kronenberg F, Eckardt KU: (2021) Rare genetic variants affecting urine metabolite levels link population variation to inborn errors of metabolism. Nat Commun. 2021;12(1):
Steinbrenner I, Schultheiss UT, Kotsis F, Schlosser P, Stockmann H, Mohney RP, Schmid M, Oefner PJ, Eckardt KU, Köttgen A, Sekula P, German Chronic Kidney Disease Investigators , Eckardt KU, Meiselbach H, Schneider MP, Schiffer M, Prokosch HU, Bärthlein B, Beck A, Reis A, Ekici AB, Becker S, Becker-Grosspitsch D, Alberth-Schmidt U, Hausknecht B, Weigel A, Walz G, Köttgen A, Schultheiß UT, Kotsis F, Meder S, Mitsch E, Reinhard U, Floege J, Saritas T, Schaeffner E, Baid-Agrawal S, Theisen K, Haller H, Menne J, Zeier M, Sommerer C, Theilinger J, Wolf G, Busch M, Paul R, Sitter T, Wanner C, Krane V, Börner-Klein A, Bauer B, Kronenberg F, Raschenberger J, Kollerits B, Forer L, Schönherr S, Weissensteiner H, Oefner P, Gronwald W, Schmid M, Nadal J: (2021) Urine Metabolite Levels, Adverse Kidney Outcomes, and Mortality in CKD Patients: A Metabolome-wide Association Study. Am J Kidney Dis. 2021;78(5): 669-677.e1
Pammer LM, Lamina C, Schultheiss UT, Kotsis F, Kollerits B, Stockmann H, Lipovsek J, Meiselbach H, Busch M, Eckardt KU, Kronenberg F, GCKD Investigators: (2021) Association of the metabolic syndrome with mortality and major adverse cardiac events: A large chronic kidney disease cohort. J Intern Med. 2021;290(6): 1219-1232
Schachtl-Riess JF, Kheirkhah A, Grüneis R, Di Maio S, Schoenherr S, Streiter G, Losso JL, Paulweber B, Eckardt KU, Köttgen A, Lamina C, Kronenberg F, Coassin S, GCKD Investigators , Eckardt KU, Meiselbach H, Schneider MP, Schiffer M, Prokosch HU, Bärthlein B, Beck A, Reis A, Ekici AB, Becker S, Becker-Grosspitsch D, Alberth-Schmidt U, Hausknecht B, Weigel A, Walz G, Köttgen A, Schultheiß UT, Kotsis F, Meder S, Mitsch E, Reinhard U, Floege J, Saritas T, Schaeffner E, Baid-Agrawal S, Theisen K, Haller H, Menne J, Zeier M, Sommerer C, Theilinger J, Wolf G, Busch M, Paul R, Sitter T, Wanner C, Krane V, Börner-Klein A, Bauer B, Kronenberg F, Raschenberger J, Kollerits B, Forer L, Schönherr S, Weissensteiner H, Oefner P, Gronwald W, Schmid M, Nadal J: (2021) Frequent LPA KIV-2 Variants Lower Lipoprotein(a) Concentrations and Protect Against Coronary Artery Disease. J Am Coll Cardiol. 2021;78(5): 437-449
Schachtl-Riess JF, Kheirkhah A, Gruneis R, Di Maio S, Schoenherr S, Streiter G, Losso JL, Paulweber B, Eckardt KU, Kottgen A, Lamina C, Kronenberg F, Coassin S: (2021) HIGHLY FREQUENT VARIANTS HIDDEN IN THE KIV-2 REGION OF LPA REGULATE LIPOPROTEIN(A) CONCENTRATIONS AND LOWER CORONARY ARTERY DISEASE RISK Atherosclerosis. 2021;331(): E6-E6
Schwaiger JP, Kollerits B, Steinbrenner I, Weissensteiner H, Schoenherr S, Forer L, Kotsis F, Schneider MP, Schultheiss UT, Wanner C, Koettgen A, Eckardt KU, Kronenberg F: (2021) APOLIPOPROTEIN A-IV CONCENTRATIONS AND CLINICAL OUTCOMES IN CHRONIC KIDNEY DISEASE PATIENTS: RESULTS FROM THE GERMAN CHRONIC KIDNEY DISEASE (GCKD) STUDY Atherosclerosis. 2021;331(): E161-E161
Kheirkhah A, Lamina C, Kollerits B, Schachtl-Riess JF, Schultheiss UT, Forer L, Sekula P, Ottgen FKAK, Eckardt KU, Kronenberg F: (2021) STRONG ASSOCIATION BETWEEN SERUM PCSK9 AND CARDIOVASCULAR DISEASE IN PATIENTS WITH MODERATE CHRONIC KIDNEY DISEASES THE GCKD STUDY Atherosclerosis. 2021;331(): E48-E48
Bellocchio F, Lonati C, Ion Titapiccolo J, Nadal J, Meiselbach H, Schmid M, Baerthlein B, Tschulena U, Schneider M, Schultheiss UT, Barbieri C, Moore C, Steppan S, Eckardt KU, Stuard S, Neri L: (2021) Validation of a Novel Predictive Algorithm for Kidney Failure in Patients Suffering from Chronic Kidney Disease: The Prognostic Reasoning System for Chronic Kidney Disease (PROGRES-CKD). Int J Environ Res Public Health. 2021;18(23):
Schlosser P, Tin A, Matias-Garcia PR, Thio CHL, Joehanes R, Liu H, Weihs A, Yu Z, Hoppmann A, Grundner-Culemann F, Min JL, Adeyemo AA, Agyemang C, Ärnlöv J, Aziz NA, Baccarelli A, Bochud M, Brenner H, Breteler MMB, Carmeli C, Chaker L, Chambers JC, Cole SA, Coresh J, Corre T, Correa A, Cox SR, de Klein N, Delgado GE, Domingo-Relloso A, Eckardt KU, Ekici AB, Endlich K, Evans KL, Floyd JS, Fornage M, Franke L, Fraszczyk E, Gao X, Gào X, Ghanbari M, Ghasemi S, Gieger C, Greenland P, Grove ML, Harris SE, Hemani G, Henneman P, Herder C, Horvath S, Hou L, Hurme MA, Hwang SJ, Jarvelin MR, Kardia SLR, Kasela S, Kleber ME, Koenig W, Kooner JS, Kramer H, Kronenberg F, Kühnel B, Lehtimäki T, Lind L, Liu D, Liu Y, Lloyd-Jones DM, Lohman K, Lorkowski S, Lu AT, Marioni RE, März W, McCartney DL, Meeks KAC, Milani L, Mishra PP, Nauck M, Navas-Acien A, Nowak C, Peters A, Prokisch H, Psaty BM, Raitakari OT, Ratliff SM, Reiner AP, Rosas SE, Schöttker B, Schwartz J, Sedaghat S, Smith JA, Sotoodehnia N, Stocker HR, Stringhini S, Sundström J, Swenson BR, Tellez-Plaza M, van Meurs JBJ, van Vliet-Ostaptchouk JV, Venema A, Verweij N, Walker RM, Wielscher M, Winkelmann J, Wolffenbuttel BHR, Zhao W, Zheng Y, Estonian Biobank Research Team , Genetics of DNA Methylation Consortium , Loh M, Snieder H, Levy D, Waldenberger M, Susztak K, Köttgen A, Teumer A, Milani L: (2021) Meta-analyses identify DNA methylation associated with kidney function and damage. Nat Commun. 2021;12(1):
Tin A, Schlosser P, Matias-Garcia PR, Thio CHL, Joehanes R, Liu H, Yu Z, Weihs A, Hoppmann A, Grundner-Culemann F, Min JL, Kuhns VLH, Adeyemo AA, Agyemang C, Ärnlöv J, Aziz NA, Baccarelli A, Bochud M, Brenner H, Bressler J, Breteler MMB, Carmeli C, Chaker L, Coresh J, Corre T, Correa A, Cox SR, Delgado GE, Eckardt KU, Ekici AB, Endlich K, Floyd JS, Fraszczyk E, Gao X, Gào X, Gelber AC, Ghanbari M, Ghasemi S, Gieger C, Greenland P, Grove ML, Harris SE, Hemani G, Henneman P, Herder C, Horvath S, Hou L, Hurme MA, Hwang SJ, Kardia SLR, Kasela S, Kleber ME, Koenig W, Kooner JS, Kronenberg F, Kühnel B, Ladd-Acosta C, Lehtimäki T, Lind L, Liu D, Lloyd-Jones DM, Lorkowski S, Lu AT, Marioni RE, März W, McCartney DL, Meeks KAC, Milani L, Mishra PP, Nauck M, Nowak C, Peters A, Prokisch H, Psaty BM, Raitakari OT, Ratliff SM, Reiner AP, Schöttker B, Schwartz J, Sedaghat S, Smith JA, Sotoodehnia N, Stocker HR, Stringhini S, Sundström J, Swenson BR, van Meurs JBJ, van Vliet-Ostaptchouk JV, Venema A, Völker U, Winkelmann J, Wolffenbuttel BHR, Zhao W, Zheng Y, Estonian Biobank Research Team , Genetics of DNA Methylation Consortium , Loh M, Snieder H, Waldenberger M, Levy D, Akilesh S, Woodward OM, Susztak K, Teumer A, Köttgen A: (2021) Epigenome-wide association study of serum urate reveals insights into urate co-regulation and the SLC2A9 locus. Nat Commun. 2021;12(1):
Pfau A, Wytopil M, Chauhan K, Reichel M, Coca S, Aronson PS, Eckardt KU, Knauf F: (2021) Author Reply to Comment on "Assessment of Plasma Oxalate Concentration in Patients With CKD" by Oka et al. Kidney Int Rep. 2021;6(4): 1194-1195
Kotsis F, Schultheiss UT, Wuttke M, Schlosser P, Mielke J, Becker MS, Oefner PJ, Karoly ED, Mohney RP, Eckardt KU, Sekula P, Köttgen A, GCKD Investigators , Eckardt KU, Meiselbach H, Schneider MP, Schiffer M, Prokosch HU, Bärthlein B, Beck A, Reis A, Ekici AB, Becker S, Becker-Grosspitsch D, Alberth-Schmidt U, Hausknecht B, Weigel A, Walz G, Köttgen A, Schultheiß UT, Kotsis F, Meder S, Mitsch E, Reinhard U, Floege J, Saritas T, Schaeffner E, Baid-Agrawal S, Theisen K, Haller H, Menne J, Zeier M, Sommerer C, Theilinger J, Wolf G, Busch M, Paul R, Sitter T, Wanner C, Krane V, Börner-Klein A, Bauer B, Kronenberg F, Raschenberger J, Kollerits B, Forer L, Schönherr S, Weissensteiner H, Oefner P, Gronwald W, Schmid M, Nadal J: (2021) Self-Reported Medication Use and Urinary Drug Metabolites in the German Chronic Kidney Disease (GCKD) Study. J Am Soc Nephrol. 2021;32(9): 2315-2329
Schultheiss UT, Steinbrenner I, Nauck M, Schneider MP, Kotsis F, Baid-Agrawal S, Schaeffner E, Eckardt KU, Köttgen A, Sekula P, GCKD investigators: (2021) Thyroid function, renal events and mortality in chronic kidney disease patients: the German Chronic Kidney Disease study. Clin Kidney J. 2021;14(3): 959-968
Steinbrenner I, Cheng YR, Nadal J, Schmid M, Kotsis FK, Meiselbach H, Schneider M, Krane V, Nauck M, Eckardt KU, Koettgen A, Sekula P, Schultheiss UT: (2021) OSTEOPONTIN AND ITS ASSOCIATION WITH ADVERSE EVENTS IN THE GERMAN CHRONIC KIDNEY DISEASE STUDY Nephrol Dial Transplant. 2021;36 Suppl 1():
Kotsis FK, Schultheiss UT, Wuttke M, Schlosser P, Oefner P, Mohney RP, Eckardt KU, Mielke J, Becker M, Sekula P, Koellgen A: (2021) SELF-REPORTED MEDICATION USE AND URINARY DRUG METABOLITES IN THE GERMAN CHRONIC KIDNEY DISEASE (GCKD) STUDY: A PHARMACOMETABOLOMIC APPROACH Nephrol Dial Transplant. 2021;36 Suppl 1(): 305-305
Steinbrenner I, Schultheiss UT, Kotsis FK, Schlosser P, Stockmann H, Mohney RP, Schmid M, Oefner P, Eckardt KU, Koettgen A, Sekula P: (2021) URINE METABOLITE LEVELS OF CKD PATIENTS ARE ASSOCIATED WITH ADVERSE KIDNEY OUTCOMES AND MORTALITY Nephrol Dial Transplant. 2021;36 Suppl 1():
Cho Y, Tong A, Craig JC, Mustafa RA, Chapman A, Perrone RD, Ahn C, Fowler K, Torres V, Gansevoort RT, Ong ACM, Coolican H, Tze-Wah Kao J, Harris T, Gutman T, Shen JI, Viecelli AK, Johnson DW, Au E, El-Damanawi R, Logeman C, Ju A, Manera KE, Chonchol M, Odland D, Baron D, Pei Y, Sautenet B, Rastogi A, Sharma A, Rangan G, SONG-PKD Workshop Investigators , Levin A, Yu A, Ong A, Thompson A, Tong A, Baumgart A, Bernier-Jean A, Kelly A, Viecelli A, Mallett A, Ju A, Wang A, Rastog A, Sharma A, Nadeau-Fredette AC, Chapman A, Teixeira-Pinto A, Kelly A, Gillespie B, Sautenet B, Canaud B, Manns B, Hemmelgarn B, Hanson C, Hawley C, Pollock C, Logeman C, Chao CT, Rutherford C, Ahn C, Sumpton D, Harris D, Johnson D, Wheeler D, Mekahli D, O'Donoghue D, Peters D, Oberdhan D, Balovlenkov E, O'Lone E, Au E, Tentori F, Czerwiec F, Oskoui FR, Rangan G, Germino G, Park H, Htay H, Ryu H, Norton J, Shen J, Gill J, Craig JC, Kao J, Eckardt KU, Manera K, Van KL, Guay-Woodford L, Krishnan M, Hogan M, Howell M, Park M, Mrug M, Chonchol M, Ta M, Evangelidis N, Harris P, Tugwell P, Garimella P, El-Damanawi R, Krishnasamy R, Mustafa R, McGee R, Pecoits-Filho R, Gansevoort R, Perrone R, Torra R, Crowe S, Anumudu S, Chan S, Bernays S, Horie S, Carter S, Palmer S, Mendley S, Gutman T, Watnick T, Hiemstra T, Weimbs T, Torres V, Jha V, van Biesen W, Winkelmayer W, Cho Y, Pei Y, Oh YK, Baron D, Clark D, McGinty-Poteet D, Odland D, King E, Vickers F, Coolican H, Odland J, Fowler K, Lee L, Vickers M, Johnston-Clark M, Dorsey R, Harris T, Baron Z: (2021) Establishing a Core Outcome Set for Autosomal Dominant Polycystic Kidney Disease: Report of the Standardized Outcomes in Nephrology-Polycystic Kidney Disease (SONG-PKD) Consensus Workshop. Am J Kidney Dis. 2021;77(2): 255-263
Cheng Y, Schlosser P, Hertel J, Sekula P, Oefner PJ, Spiekerkoetter U, Mielke J, Freitag DF, Schmidts M, GCKD Investigators , Kronenberg F, Eckardt KU, Thiele I, Li Y, Köttgen A, Oefner PJ, Kronenberg F, Eckardt KU: (2021) Author Correction: Rare genetic variants affecting urine metabolite levels link population variation to inborn errors of metabolism. Nat Commun. 2021;12(1):
Hauser T, Dornberger V, Malzahn U, Grebe SJ, Liu D, Störk S, Nauck M, Friedrich N, Dörr M, Wanner C, Krane V, Hammer F, MiREnDa Study Group , Collaborating investigators (sites) , Berweck S, Biggar P, Blaser C, Bochannek T, Breunig F, Brunner M, Büschges-Seraphin B, Büttner S, Cakmak A, Döltz T, Dörken M, Eckardt KU, Fink H, Fischer S, Freisinger W, Freiwald T, Gebhardt J, Geiger H, Götz R, Goßmann J, Hammerstingl R, Harazny J, Heckel M, Heyd-Schramm A, Hoyer J, Janka R, Jung O, Ketteler M, Klaeffling C, Kleinert C, Kleinert M, Klingbeil A, Klink T, Koch BF, Kosowski J, Leidig M, Lutz J, Marwan M, Moritz M, Moye B, Naujoks H, Netzer KO, Raff U, Reichert C, Reimer I, Ribel J, Richter S, Ritter C, Rudolf S, Schamberger B, Schmid M, Schmiedeke T, Schmitt A, Schneider H, Schneider R, Schneuzer C, Schöffauer M, Schramm L, Schütterle S, Schwedler S, Sobkowiak E, Sollinger D, Strutz F, Toncar S, Vasiljuk V, Vogl T, Walther T, Weinmann-Menke J, Wirth B, Witsch H, Würmell P, Zeltner R, Zimmermann J: (2021) The effect of spironolactone on diastolic function in haemodialysis patients. Int J Cardiovasc Imaging. 2021;37(6): 1927-1936
Gregorich M, Heinzel A, Kammer M, Meiselbach H, Böger C, Eckardt KU, Mayer G, Heinze G, Oberbauer R: (2021) A prediction model for the decline in renal function in people with type 2 diabetes mellitus: study protocol. Diagn Progn Res. 2021;5(1):
Cejka V, Stoerk S, Nadal J, Schultheiss UT, Koettgen A, Sommerer C, Sitter T, Meiselbach H, Busch M, Schneider M, Saritas T, Kotsis FK, Wanner C, Eckardt KU, Krane V: (2020) PROGNOSTIC IMPACT OF NECK CIRCUMFERENCE ON CARDIVASCULAR OUTCOMES AND MORTALITY IN PATIENTS WITH MODERATE CHRONIC KIDNEY DISEASE: AN ANALYSIS FROM THE GERMAN CHRONIC KIDNEY DISEASE (GCKD) STUDY Nephrol Dial Transplant. 2020;35 Suppl 3(): 1110-1110
Levin A, Agarwal R, Herrington WG, Heerspink HL, Mann JFE, Shahinfar S, Tuttle KR, Donner JA, Jha V, Nangaku M, de Zeeuw D, Jardine MJ, Mahaffey KW, Thompson AM, Beaucage M, Chong K, Roberts GV, Sunwold D, Vorster H, Warren M, Damster S, Malik C, Perkovic V, participant authors of the International Society of Nephrology’s 1st International Consensus Meeting on Defining Kidney Failure in Clinical Trials , Anand S, Argent N, Babak E, Banerjee D, Barratt J, Bello AK, Bernardo AA, Blais J, Canovatchel W, Caskey FJ, Coresh J, de Boer IH, Eckardt KU, Evans RD, Feldman HI, Fogo AB, Gudmundsdottir H, Hamano T, Harris DCH, Hauske SJ, Haynes R, Herzog CA, Hiemstra T, Idorn T, Inker L, Ishida JH, Johnson DW, Jones-Burton C, Joseph A, Koitka-Weber A, Kretzler M, Lawatscheck R, Liew A, Moist L, Naicker S, Nakashima R, Patel U, Filho RP, Rose JB, Rosenberg NL, Sinsakul M, Smoyer WE, Sola L, Sood AR, Stengel B, Taal MW, Tanaka M, Tonelli M, Tong A, Toto R, Trask M, Ulasi II, Wanner C, Wheeler DC, Wolthers BO, Wright HM, Yamada Y, Zakharova E: (2020) International consensus definitions of clinical trial outcomes for kidney failure: 2020. Kidney Int. 2020;98(4): 849-859
Pfau A, Wytopil M, Chauhan K, Reichel M, Coca SG, Aronson PS, Eckardt KU, Knauf F: (2020) Assessment of Plasma Oxalate Concentration in Patients With CKD. Kidney Int Rep. 2020;5(11): 2013-2020
Saritas T, Reinartz SD, Nadal J, Schmoee J, Schmid M, Marwan M, Achenbach S, Störk S, Wanner C, Eckardt KU, Floege J, Peter Schneider M, Schlieper G: (2020) Epicardial fat, cardiovascular risk factors and calcifications in patients with chronic kidney disease. Clin Kidney J. 2020;13(4): 571-579
Dannewitz B, Sommerer C, Stölzel P, Baid-Agrawal S, Nadal J, Bärthlein B, Wanner C, Eckardt KU, Zeier M, Schlagenhauf U, Krane V, Jockel-Schneider Y: (2020) Status of periodontal health in German patients suffering from chronic kidney disease-Data from the GCKD study. J Clin Periodontol. 2020;47(1): 19-29
Heindel J, Baid-Agrawal S, Rebholz CM, Nadal J, Schmid M, Schaeffner E, Schneider MP, Meiselbach H, Kaesler N, Bergmann M, Ernst S, Krane V, Eckardt KU, Floege J, Schlieper G, Saritas T, GCKD Study Investigators: (2020) Association Between Dietary Patterns and Kidney Function in Patients With Chronic Kidney Disease: A Cross-Sectional Analysis of the German Chronic Kidney Disease Study. J Ren Nutr. 2020;30(4): 296-304
Müller HHO, Lücke C, Englbrecht M, Wiesener MS, Siller T, Eckardt KU, Kornhuber J, Maler JM: (2020) Kidney-transplant patients receiving living- or dead-donor organs have similar psychological outcomes (findings from the PI-KT study). Ment Illn. 2020;12(1): 17-22
Buchholz B, Eckardt KU: (2020) Role of oxygen and the HIF-pathway in polycystic kidney disease. Cell Signal. 2020;69():
Fazzini F, Lamina C, Raschenberger J, Schultheiss UT, Kotsis F, Schönherr S, Weissensteiner H, Forer L, Steinbrenner I, Meiselbach H, Bärthlein B, Wanner C, Eckardt KU, Köttgen A, Kronenberg F, GCKD Investigators , Eckardt KU, Meiselbach H, Schneider M, Dienemann T, Prokosch HU, Bärthlein B, Beck A, Ganslandt T, Reis A, Ekici AB, Avendaño S, Becker-Grosspitsch D, Alberth-Schmidt U, Hausknecht B, Zitzmann R, Weigel A, Walz G, Köttgen A, Schultheiß UT, Kotsis F, Meder S, Mitsch E, Reinhard U, Floege J, Schlieper G, Saritas T, Ernst S, Beaujean N, Schaeffner E, Baid-Agrawal S, Theisen K, Haller H, Menne J, Zeier M, Sommerer C, Woitke R, Wolf G, Busch M, Fuß R, Sitter T, Blank C, Wanner C, Krane V, Börner-Klein A, Bauer B, Kronenberg F, Raschenberger J, Kollerits B, Forer L, Schönherr S, Weissensteiner H, Oefner P, Gronwald W, Zacharias H, Schmid M, Nadal J: (2020) Results from the German Chronic Kidney Disease (GCKD) study support association of relative telomere length with mortality in a large cohort of patients with moderate chronic kidney disease. Kidney Int. 2020;98(2): 488-497
Matsushita K, Jassal SK, Sang Y, Ballew SH, Grams ME, Surapaneni A, Arnlov J, Bansal N, Bozic M, Brenner H, Brunskill NJ, Chang AR, Chinnadurai R, Cirillo M, Correa A, Ebert N, Eckardt KU, Gansevoort RT, Gutierrez O, Hadaegh F, He J, Hwang SJ, Jafar TH, Kayama T, Kovesdy CP, Landman GW, Levey AS, Lloyd-Jones DM, Major RW, Miura K, Muntner P, Nadkarni GN, Naimark DM, Nowak C, Ohkubo T, Pena MJ, Polkinghorne KR, Sabanayagam C, Sairenchi T, Schneider MP, Shalev V, Shlipak M, Solbu MD, Stempniewicz N, Tollitt J, Valdivielso JM, van der Leeuw J, Wang AY, Wen CP, Woodward M, Yamagishi K, Yatsuya H, Zhang L, Schaeffner E, Coresh J: (2020) Incorporating kidney disease measures into cardiovascular risk prediction: Development and validation in 9 million adults from 72 datasets. EClinicalMedicine. 2020;27():
Di Maio S, Grüneis R, Streiter G, Lamina C, Maglione M, Schoenherr S, Öfner D, Thorand B, Peters A, Eckardt KU, Köttgen A, Kronenberg F, Coassin S: (2020) Investigation of a nonsense mutation located in the complex KIV-2 copy number variation region of apolipoprotein(a) in 10,910 individuals. Genome Med. 2020;12(1):
Sekula P, Tin A, Schultheiss UT, Baid-Agrawal S, Mohney RP, Steinbrenner I, Yu B, Luo S, Boerwinkle E, Eckardt KU, Coresh J, Grams ME, Kӧttgen A: (2020) Urine 6-Bromotryptophan: Associations with Genetic Variants and Incident End-Stage Kidney Disease. Sci Rep. 2020;10(1):
Xie J, Liu L, Mladkova N, Li Y, Ren H, Wang W, Cui Z, Lin L, Hu X, Yu X, Xu J, Liu G, Caliskan Y, Sidore C, Balderes O, Rosen RJ, Bodria M, Zanoni F, Zhang JY, Krithivasan P, Mehl K, Marasa M, Khan A, Ozay F, Canetta PA, Bomback AS, Appel GB, Sanna-Cherchi S, Sampson MG, Mariani LH, Perkowska-Ptasinska A, Durlik M, Mucha K, Moszczuk B, Foroncewicz B, Pączek L, Habura I, Ars E, Ballarin J, Mani LY, Vogt B, Ozturk S, Yildiz A, Seyahi N, Arikan H, Koc M, Basturk T, Karahan G, Akgul SU, Sever MS, Zhang D, Santoro D, Bonomini M, Londrino F, Gesualdo L, Reiterova J, Tesar V, Izzi C, Savoldi S, Spotti D, Marcantoni C, Messa P, Galliani M, Roccatello D, Granata S, Zaza G, Lugani F, Ghiggeri G, Pisani I, Allegri L, Sprangers B, Park JH, Cho B, Kim YS, Kim DK, Suzuki H, Amoroso A, Cattran DC, Fervenza FC, Pani A, Hamilton P, Harris S, Gupta S, Cheshire C, Dufek S, Issler N, Pepper RJ, Connolly J, Powis S, Bockenhauer D, Stanescu HC, Ashman N, Loos RJF, Kenny EE, Wuttke M, Eckardt KU, Köttgen A, Hofstra JM, Coenen MJH, Kiemeney LA, Akilesh S, Kretzler M, Beck LH, Stengel B, Debiec H, Ronco P, Wetzels JFM, Zoledziewska M, Cucca F, Ionita-Laza I, Lee H, Hoxha E, Stahl RAK, Brenchley P, Scolari F, Zhao MH, Gharavi AG, Kleta R, Chen N, Kiryluk K: (2020) The genetic architecture of membranous nephropathy and its potential to improve non-invasive diagnosis. Nat Commun. 2020;11(1):
Steubl D, Schneider MP, Meiselbach H, Nadal J, Schmid MC, Saritas T, Krane V, Sommerer C, Baid-Agrawal S, Voelkl J, Kotsis F, Köttgen A, Eckardt KU, Scherberich JE, GCKD Study Investigators: (2020) Association of Serum Uromodulin with Death, Cardiovascular Events, and Kidney Failure in CKD. Clin J Am Soc Nephrol. 2020;15(5): 616-624
Schlosser P, Li Y, Sekula P, Raffler J, Grundner-Culemann F, Pietzner M, Cheng Y, Wuttke M, Steinbrenner I, Schultheiss UT, Kotsis F, Kacprowski T, Forer L, Hausknecht B, Ekici AB, Nauck M, Völker U, GCKD Investigators , Walz G, Oefner PJ, Kronenberg F, Mohney RP, Köttgen M, Suhre K, Eckardt KU, Kastenmüller G, Köttgen A: (2020) Genetic studies of urinary metabolites illuminate mechanisms of detoxification and excretion in humans. Nat Genet. 2020;52(2): 167-176
Maas R, Mieth M, Titze SI, Hübner S, Fromm MF, Kielstein JT, Schmid M, Köttgen A, Kronenberg F, Krane V, Hausknecht B, Eckardt KU, Schneider MP, GCKD study Investigators , Eckardt KU, Meiselbach H, Schneider M, Dienemann T, Prokosch HU, Bärthlein B, Reis A, Ekici AB, Avendano S, Becker-Grosspitsch D, Alberth-Schmidt U, Hausknecht B, Zitzmann R, Weigel A, Beck A, Ganslandt T, Walz G, Köttgen A, Schultheiß U, Kotsis F, Meder S, Mitsch E, Reinhard U, Floege J, Schlieper G, Saritas T, Ernst S, Beaujean N, Schaeffner E, Baid-Agrawal S, Theisen K, Haller H, Menne J, Zeier M, Sommerer C, Woitke R, Wolf G, Busch M, Fuß R, Sitter T, Blank C, Wanner C, Krane V, Börner-Klein A, Cäsar S, Bauer B, Kronenberg F, Raschenberger J, Kollerits B, Forer L, Schönherr S, Weissensteiner H, Oefner P, Gronwald W, Zacharias H, Schmid M, Nadal J: (2020) Drugs linked to plasma homoarginine in chronic kidney disease patients-a cross-sectional analysis of the German Chronic Kidney Disease cohort. Nephrol Dial Transplant. 2020;35(7): 1187-1195
Hammer F, Malzahn U, Donhauser J, Betz C, Schneider MP, Grupp C, Pollak N, Störk S, Wanner C, Krane V, MiREnDa Study Group , Berweck S, Betz C, Biggar P, Blaser C, Bochannek T, Breunig F, Brunner M, Büschges-Seraphin B, Büttner S, Cakmak A, Donhauser J, Döltz T, Dörken M, Eckardt KU, Fink H, Fischer S, Freisinger W, Freiwald T, Gebhardt J, Geiger H, Götz R, Goßmann J, Grupp C, Hammer F, Hammerstingl R, Harazny J, Heckel M, Heyd-Schramm A, Hoyer J, Janka R, Jung O, Ketteler M, Klaeffling C, Kleinert C, Kleinert M, Klingbeil A, Klink T, Koch BF, Kosowski J, Krane V, Leidig M, Lutz J, Marwan M, Moritz M, Moye B, Naujoks H, Netzer KO, Raff U, Reichert C, Reimer I, Ribel J, Richter S, Ritter C, Rudolf S, Schamberger B, Schmid M, Schmiedeke T, Schmitt A, Schneider H, Schneider MP, Schneider R, Schneuzer C, Schöffauer M, Schramm L, Schütterle S, Schwedler S, Sobkowiak E, Sollinger D, Strutz F, Toncar S, Vasiljuk V, Vogl T, Walther T, Wanner C, Weinmann-Menke J, Wirth B, Witsch H, Würmell P, Zeltner R, Zimmermann J: (2019) A randomized controlled trial of the effect of spironolactone on left ventricular mass in hemodialysis patients. Kidney Int. 2019;95(4): 983-991
Schneider MP, Scheppach JB, Raff U, Toncar S, Ritter C, Klink T, Störk S, Wanner C, Schlieper G, Saritas T, Reinartz SD, Floege J, Friedrich N, Janka R, Uder M, Schmieder RE, Eckardt KU: (2019) Left Ventricular Structure in Patients With Mild-to-Moderate CKD-a Magnetic Resonance Imaging Study. Kidney Int Rep. 2019;4(2): 267-274
Mc Causland FR, Claggett B, Burdmann EA, Chertow GM, Cooper ME, Eckardt KU, Ivanovich P, Levey AS, Lewis EF, McGill JB, McMurray JJV, Parfrey P, Parving HH, Remuzzi G, Singh AK, Solomon SD, Toto RD, Pfeffer MA: (2019) Treatment of Anemia With Darbepoetin Prior to Dialysis Initiation and Clinical Outcomes: Analyses From the Trial to Reduce Cardiovascular Events With Aranesp Therapy (TREAT). Am J Kidney Dis. 2019;73(3): 309-315
Schley G, Klanke B, Kalucka J, Schatz V, Daniel C, Mayer M, Goppelt-Struebe M, Herrmann M, Thorsteinsdottir M, Palsson R, Beneke A, Katschinski DM, Burzlaff N, Eckardt KU, Weidemann A, Jantsch J, Willam C: (2019) Mononuclear phagocytes orchestrate prolyl hydroxylase inhibition-mediated renoprotection in chronic tubulointerstitial nephritis. Kidney Int. 2019;96(2): 378-396
Fandrey J, Schödel J, Eckardt KU, Katschinski DM, Wenger RH: (2019) Now a Nobel gas: oxygen. Pflugers Arch. 2019;471(11-12): 1343-1358
Schley G, Jordan J, Ellmann S, Rosen S, Eckardt KU, Uder M, Willam C, Bäuerle T: (2019) Correction: Multiparametric magnetic resonance imaging of experimental chronic kidney disease: A quantitative correlation study with histology. PLoS ONE. 2019;14(6):
Henze LA, Luong TTD, Boehme B, Masyout J, Schneider MP, Brachs S, Lang F, Pieske B, Pasch A, Eckardt KU, Voelkl J, Alesutan I: (2019) Impact of C-reactive protein on osteo-/chondrogenic transdifferentiation and calcification of vascular smooth muscle cells. Aging (Albany NY). 2019;11(15): 5445-5462
Schneider MP, Eckardt KU: (2019) Risk Scores in Patients with Chronic Kidney Disease Dtsch Med Wochenschr. 2019;144(11): 739-742
Fazzini F, Lamina C, Fendt L, Schultheiss UT, Kotsis F, Hicks AA, Meiselbach H, Weissensteiner H, Forer L, Krane V, Eckardt KU, Köttgen A, Kronenberg F, GCKD Investigators , Eckardt KU, Meiselbach H, Schneider M, Dienemann T, Prokosch HU, Bärthlein B, Beck A, Ganslandt T, Reis A, Ekici AB, Avendano S, Becker-Grosspitsch D, Alberth-Schmidt U, Hausknecht B, Zitzmann R, Weigel A, Walz G, Köttgen A, Schultheiß U, Kotsis F, Meder S, Mitsch E, Reinhard U, Floege J, Schlieper G, Saritas T, Ernst S, Beaujean N, Schaeffner E, Baid-Agrawal S, Theisen K, Haller H, Menne J, Zeier M, Sommerer C, Woitke R, Wolf G, Busch M, Fuß R, Sitter T, Blank C, Wanner C, Krane V, Börner-Klein A, Bauer B, Kronenberg F, Raschenberger J, Kollerits B, Forer L, Schönherr S, Weissensteiner H, Oefner P, Gronwald W, Zacharias H, Schmid M, Nadal J: (2019) Mitochondrial DNA copy number is associated with mortality and infections in a large cohort of patients with chronic kidney disease. Kidney Int. 2019;96(2): 480-488
Steubl D, Schneider M, Meiselbach H, Nadal J, Saritas T, Krane V, Sommerer C, Baid-Agrawal S, Koettgen A, Eckardt KU, Scherberich J: (2019) ASSOCIATION OF SERUM UROMODULIN WITH DEATH, CARDIOVASCULAR AND RENAL EVENTS: RESULTS FROM THE GERMAN CHRONIC KIDNEY DISEASE (GCKD) STUDY Nephrol Dial Transplant. 2019;34 Suppl 1(): 158-158
Schneider M, Meiselbach H, Schulmann T, Cornea G, Eckardt KU: (2019) RENIN-ANGIOTENSIN-ALDOSTERONE SYSTEM INHIBITOR THERAPY IN PATIENTS WITH CHRONIC KIDNEY DISEASE: AN ANALYSIS FROM THE GERMAN CHRONIC KIDNEY DISEASE STUDY Nephrol Dial Transplant. 2019;34 Suppl 1():
Wuttke M, Li Y, Li M, Sieber KB, Feitosa MF, Gorski M, Tin A, Wang L, Chu AY, Hoppmann A, Kirsten H, Giri A, Chai JF, Sveinbjornsson G, Tayo BO, Nutile T, Fuchsberger C, Marten J, Cocca M, Ghasemi S, Xu Y, Horn K, Noce D, van der Most PJ, Sedaghat S, Yu Z, Akiyama M, Afaq S, Ahluwalia TS, Almgren P, Amin N, Ärnlöv J, Bakker SJL, Bansal N, Baptista D, Bergmann S, Biggs ML, Biino G, Boehnke M, Boerwinkle E, Boissel M, Bottinger EP, Boutin TS, Brenner H, Brumat M, Burkhardt R, Butterworth AS, Campana E, Campbell A, Campbell H, Canouil M, Carroll RJ, Catamo E, Chambers JC, Chee ML, Chee ML, Chen X, Cheng CY, Cheng Y, Christensen K, Cifkova R, Ciullo M, Concas MP, Cook JP, Coresh J, Corre T, Sala CF, Cusi D, Danesh J, Daw EW, de Borst MH, De Grandi A, de Mutsert R, de Vries APJ, Degenhardt F, Delgado G, Demirkan A, Di Angelantonio E, Dittrich K, Divers J, Dorajoo R, Eckardt KU, Ehret G, Elliott P, Endlich K, Evans MK, Felix JF, Foo VHX, Franco OH, Franke A, Freedman BI, Freitag-Wolf S, Friedlander Y, Froguel P, Gansevoort RT, Gao H, Gasparini P, Gaziano JM, Giedraitis V, Gieger C, Girotto G, Giulianini F, Gögele M, Gordon SD, Gudbjartsson DF, Gudnason V, Haller T, Hamet P, Harris TB, Hartman CA, Hayward C, Hellwege JN, Heng CK, Hicks AA, Hofer E, Huang W, Hutri-Kähönen N, Hwang SJ, Ikram MA, Indridason OS, Ingelsson E, Ising M, Jaddoe VWV, Jakobsdottir J, Jonas JB, Joshi PK, Josyula NS, Jung B, Kähönen M, Kamatani Y, Kammerer CM, Kanai M, Kastarinen M, Kerr SM, Khor CC, Kiess W, Kleber ME, Koenig W, Kooner JS, Körner A, Kovacs P, Kraja AT, Krajcoviechova A, Kramer H, Krämer BK, Kronenberg F, Kubo M, Kühnel B, Kuokkanen M, Kuusisto J, La Bianca M, Laakso M, Lange LA, Langefeld CD, Lee JJ, Lehne B, Lehtimäki T, Lieb W, LifeLines Cohort Study , Lim SC, Lind L, Lindgren CM, Liu J, Liu J, Loeffler M, Loos RJF, Lucae S, Lukas MA, Lyytikäinen LP, Mägi R, Magnusson PKE, Mahajan A, Martin NG, Martins J, März W, Mascalzoni D, Matsuda K, Meisinger C, Meitinger T, Melander O, Metspalu A, Mikaelsdottir EK, Milaneschi Y, Miliku K, Mishra PP, V. A. Million Veteran Program , Mohlke KL, Mononen N, Montgomery GW, Mook-Kanamori DO, Mychaleckyj JC, Nadkarni GN, Nalls MA, Nauck M, Nikus K, Ning B, Nolte IM, Noordam R, O'Connell J, O'Donoghue ML, Olafsson I, Oldehinkel AJ, Orho-Melander M, Ouwehand WH, Padmanabhan S, Palmer ND, Palsson R, Penninx BWJH, Perls T, Perola M, Pirastu M, Pirastu N, Pistis G, Podgornaia AI, Polasek O, Ponte B, Porteous DJ, Poulain T, Pramstaller PP, Preuss MH, Prins BP, Province MA, Rabelink TJ, Raffield LM, Raitakari OT, Reilly DF, Rettig R, Rheinberger M, Rice KM, Ridker PM, Rivadeneira F, Rizzi F, Roberts DJ, Robino A, Rossing P, Rudan I, Rueedi R, Ruggiero D, Ryan KA, Saba Y, Sabanayagam C, Salomaa V, Salvi E, Saum KU, Schmidt H, Schmidt R, Schöttker B, Schulz CA, Schupf N, Shaffer CM, Shi Y, Smith AV, Smith BH, Soranzo N, Spracklen CN, Strauch K, Stringham HM, Stumvoll M, Svensson PO, Szymczak S, Tai ES, Tajuddin SM, Tan NYQ, Taylor KD, Teren A, Tham YC, Thiery J, Thio CHL, Thomsen H, Thorleifsson G, Toniolo D, Tönjes A, Tremblay J, Tzoulaki I, Uitterlinden AG, Vaccargiu S, van Dam RM, van der Harst P, van Duijn CM, Velez Edward DR, Verweij N, Vogelezang S, Völker U, Vollenweider P, Waeber G, Waldenberger M, Wallentin L, Wang YX, Wang C, Waterworth DM, Bin Wei W, White H, Whitfield JB, Wild SH, Wilson JF, Wojczynski MK, Wong C, Wong TY, Xu L, Yang Q, Yasuda M, Yerges-Armstrong LM, Zhang W, Zonderman AB, Rotter JI, Bochud M, Psaty BM, Vitart V, Wilson JG, Dehghan A, Parsa A, Chasman DI, Ho K, Morris AP, Devuyst O, Akilesh S, Pendergrass SA, Sim X, Böger CA, Okada Y, Edwards TL, Snieder H, Stefansson K, Hung AM, Heid IM, Scholz M, Teumer A, Köttgen A, Pattaro C: (2019) A catalog of genetic loci associated with kidney function from analyses of a million individuals. Nat Genet. 2019;51(6): 957-972
Schmidt IM, Hübner S, Nadal J, Titze S, Schmid M, Bärthlein B, Schlieper G, Dienemann T, Schultheiss UT, Meiselbach H, Köttgen A, Flöge J, Busch M, Kreutz R, Kielstein JT, Eckardt KU: (2019) Patterns of medication use and the burden of polypharmacy in patients with chronic kidney disease: the German Chronic Kidney Disease study. Clin Kidney J. 2019;12(5): 663-672
Teumer A, Li Y, Ghasemi S, Prins BP, Wuttke M, Hermle T, Giri A, Sieber KB, Qiu C, Kirsten H, Tin A, Chu AY, Bansal N, Feitosa MF, Wang L, Chai JF, Cocca M, Fuchsberger C, Gorski M, Hoppmann A, Horn K, Li M, Marten J, Noce D, Nutile T, Sedaghat S, Sveinbjornsson G, Tayo BO, van der Most PJ, Xu Y, Yu Z, Gerstner L, Ärnlöv J, Bakker SJL, Baptista D, Biggs ML, Boerwinkle E, Brenner H, Burkhardt R, Carroll RJ, Chee ML, Chee ML, Chen M, Cheng CY, Cook JP, Coresh J, Corre T, Danesh J, de Borst MH, De Grandi A, de Mutsert R, de Vries APJ, Degenhardt F, Dittrich K, Divers J, Eckardt KU, Ehret G, Endlich K, Felix JF, Franco OH, Franke A, Freedman BI, Freitag-Wolf S, Gansevoort RT, Giedraitis V, Gögele M, Grundner-Culemann F, Gudbjartsson DF, Gudnason V, Hamet P, Harris TB, Hicks AA, Holm H, Foo VHX, Hwang SJ, Ikram MA, Ingelsson E, Jaddoe VWV, Jakobsdottir J, Josyula NS, Jung B, Kähönen M, Khor CC, Kiess W, Koenig W, Körner A, Kovacs P, Kramer H, Krämer BK, Kronenberg F, Lange LA, Langefeld CD, Lee JJ, Lehtimäki T, Lieb W, Lim SC, Lind L, Lindgren CM, Liu J, Loeffler M, Lyytikäinen LP, Mahajan A, Maranville JC, Mascalzoni D, McMullen B, Meisinger C, Meitinger T, Miliku K, Mook-Kanamori DO, Müller-Nurasyid M, Mychaleckyj JC, Nauck M, Nikus K, Ning B, Noordam R, Connell JO, Olafsson I, Palmer ND, Peters A, Podgornaia AI, Ponte B, Poulain T, Pramstaller PP, Rabelink TJ, Raffield LM, Reilly DF, Rettig R, Rheinberger M, Rice KM, Rivadeneira F, Runz H, Ryan KA, Sabanayagam C, Saum KU, Schöttker B, Shaffer CM, Shi Y, Smith AV, Strauch K, Stumvoll M, Sun BB, Szymczak S, Tai ES, Tan NYQ, Taylor KD, Teren A, Tham YC, Thiery J, Thio CHL, Thomsen H, Thorsteinsdottir U, Tönjes A, Tremblay J, Uitterlinden AG, van der Harst P, Verweij N, Vogelezang S, Völker U, Waldenberger M, Wang C, Wilson OD, Wong C, Wong TY, Yang Q, Yasuda M, Akilesh S, Bochud M, Böger CA, Devuyst O, Edwards TL, Ho K, Morris AP, Parsa A, Pendergrass SA, Psaty BM, Rotter JI, Stefansson K, Wilson JG, Susztak K, Snieder H, Heid IM, Scholz M, Butterworth AS, Hung AM, Pattaro C, Köttgen A: (2019) Genome-wide association meta-analyses and fine-mapping elucidate pathways influencing albuminuria. Nat Commun. 2019;10(1):
Tin A, Marten J, Halperin Kuhns VL, Li Y, Wuttke M, Kirsten H, Sieber KB, Qiu C, Gorski M, Yu Z, Giri A, Sveinbjornsson G, Li M, Chu AY, Hoppmann A, O'Connor LJ, Prins B, Nutile T, Noce D, Akiyama M, Cocca M, Ghasemi S, van der Most PJ, Horn K, Xu Y, Fuchsberger C, Sedaghat S, Afaq S, Amin N, Ärnlöv J, Bakker SJL, Bansal N, Baptista D, Bergmann S, Biggs ML, Biino G, Boerwinkle E, Bottinger EP, Boutin TS, Brumat M, Burkhardt R, Campana E, Campbell A, Campbell H, Carroll RJ, Catamo E, Chambers JC, Ciullo M, Concas MP, Coresh J, Corre T, Cusi D, Felicita SC, de Borst MH, De Grandi A, de Mutsert R, de Vries APJ, Delgado G, Demirkan A, Devuyst O, Dittrich K, Eckardt KU, Ehret G, Endlich K, Evans MK, Gansevoort RT, Gasparini P, Giedraitis V, Gieger C, Girotto G, Gögele M, Gordon SD, Gudbjartsson DF, Gudnason V, German Chronic Kidney Disease Study , Haller T, Hamet P, Harris TB, Hayward C, Hicks AA, Hofer E, Holm H, Huang W, Hutri-Kähönen N, Hwang SJ, Ikram MA, Lewis RM, Ingelsson E, Jakobsdottir J, Jonsdottir I, Jonsson H, Joshi PK, Josyula NS, Jung B, Kähönen M, Kamatani Y, Kanai M, Kerr SM, Kiess W, Kleber ME, Koenig W, Kooner JS, Körner A, Kovacs P, Krämer BK, Kronenberg F, Kubo M, Kühnel B, La Bianca M, Lange LA, Lehne B, Lehtimäki T, LifeLines Cohort Study , Liu J, Loeffler M, Loos RJF, Lyytikäinen LP, Mägi R, Mahajan A, Martin NG, März W, Mascalzoni D, Matsuda K, Meisinger C, Meitinger T, Metspalu A, Milaneschi Y, V. A. Million Veteran Program , O'Donnell CJ, Wilson OD, Gaziano JM, Mishra PP, Mohlke KL, Mononen N, Montgomery GW, Mook-Kanamori DO, Müller-Nurasyid M, Nadkarni GN, Nalls MA, Nauck M, Nikus K, Ning B, Nolte IM, Noordam R, O'Connell JR, Olafsson I, Padmanabhan S, Penninx BWJH, Perls T, Peters A, Pirastu M, Pirastu N, Pistis G, Polasek O, Ponte B, Porteous DJ, Poulain T, Preuss MH, Rabelink TJ, Raffield LM, Raitakari OT, Rettig R, Rheinberger M, Rice KM, Rizzi F, Robino A, Rudan I, Krajcoviechova A, Cifkova R, Rueedi R, Ruggiero D, Ryan KA, Saba Y, Salvi E, Schmidt H, Schmidt R, Shaffer CM, Smith AV, Smith BH, Spracklen CN, Strauch K, Stumvoll M, Sulem P, Tajuddin SM, Teren A, Thiery J, Thio CHL, Thorsteinsdottir U, Toniolo D, Tönjes A, Tremblay J, Uitterlinden AG, Vaccargiu S, van der Harst P, van Duijn CM, Verweij N, Völker U, Vollenweider P, Waeber G, Waldenberger M, Whitfield JB, Wild SH, Wilson JF, Yang Q, Zhang W, Zonderman AB, Bochud M, Wilson JG, Pendergrass SA, Ho K, Parsa A, Pramstaller PP, Psaty BM, Böger CA, Snieder H, Butterworth AS, Okada Y, Edwards TL, Stefansson K, Susztak K, Scholz M, Heid IM, Hung AM, Teumer A, Pattaro C, Woodward OM, Vitart V, Köttgen A: (2019) Target genes, variants, tissues and transcriptional pathways influencing human serum urate levels. Nat Genet. 2019;51(10): 1459-1474
Scheel J, Schieber K, Reber S, Jank S, Eckardt KU, Grundmann F, Vitinius F, de Zwaan M, Bertram A, Erim Y: (2019) Psychological processing of a kidney transplantation, perceived quality of life, and immunosuppressant medication adherence. Patient Prefer Adherence. 2019;13(): 775-782
Alencar de Pinho N, Levin A, Fukagawa M, Hoy WE, Pecoits-Filho R, Reichel H, Robinson B, Kitiyakara C, Wang J, Eckardt KU, Jha V, Oh KH, Sola L, Eder S, de Borst M, Taal M, Feldman HI, Stengel B, International Network of Chronic Kidney Disease cohort studies (iNET-CKD) , Levin A, Djurdjev O, Tang M, Fukagawa M, Fujii N, Maruyama S, Imaizumi T, Hoy WE, Zhang J, Wang Z, Healy HG, Alencar de Pinho N, Stengel B, Massy ZA, Combe C, Laville M, Filho RP, Lopes A, Reichel H, Robinson B, Pisoni R, Bieber B, Tu C, Kitiyakara C, Sangthawan P, Pichaiwong W, Klyprayong P, Feldman HI, Orlandi P, Townsend R, Go A, Wang J, Zhang L, Eckardt KU, Jha V, Kumar V, Yadav AK, Baid-Agrawal S, Oh KH, Ahn C, Chae DW, Han SH, Sola L, Rios PG, Gadola L, Lamadrid V, Eder S, Leierer J, Kerschbaum J, de Borst MH, Van Ittersum FJ, Van den Brand JA, De Jong MA, Taal MW, Shardlow A: (2019) Considerable international variation exists in blood pressure control and antihypertensive prescription patterns in chronic kidney disease. Kidney Int. 2019;96(4): 983-994
Reber S, Scheel J, Stoessel L, Schieber K, Jank S, Lüker C, Vitinius F, Grundmann F, Eckardt KU, Prokosch HU, Erim Y: (2018) Mobile Technology Affinity in Renal Transplant Recipients. Transplant Proc. 2018;50(1): 92-98
Bosch A, Scheppach JB, Harazny JM, Raff U, Eckardt KU, Schmieder RE, Schneider MP: (2018) Retinal capillary and arteriolar changes in patients with chronic kidney disease. Microvasc Res. 2018;118(): 121-127
Bergfeld L, Schrezenmeier E, Lehner L, Staeck O, Khadzhynov D, Eckardt KU, Budde K, Halleck F, Duerr M: (2018) SUCCESSFUL HCV THERAPY WITH NOVEL DAA REGIMEN IMPROVES GLUCOSE TOLERANCE AND MAY PREVENT POST-TRANSPLANT DIABETES MELLITUS IN RENAL TRANSPLANT RECIPIENTS Nephrol Dial Transplant. 2018;33(): 1600-1600
Tanaka T, Eckardt KU: (2018) HIF Activation Against CVD in CKD: Novel Treatment Opportunities. Semin Nephrol. 2018;38(3): 267-276
Li Y, Sekula P, Wuttke M, Wahrheit J, Hausknecht B, Schultheiss UT, Gronwald W, Schlosser P, Tucci S, Ekici AB, Spiekerkoetter U, Kronenberg F, Eckardt KU, Oefner PJ, Köttgen A, GCKD Investigators: (2018) Genome-Wide Association Studies of Metabolites in Patients with CKD Identify Multiple Loci and Illuminate Tubular Transport Mechanisms. J Am Soc Nephrol. 2018;29(5): 1513-1524
Schley G, Jordan J, Ellmann S, Rosen S, Eckardt KU, Uder M, Willam C, Bäuerle T: (2018) Multiparametric magnetic resonance imaging of experimental chronic kidney disease: A quantitative correlation study with histology. PLoS ONE. 2018;13(7):
Scheel JF, Schieber K, Reber S, Stoessel L, Waldmann E, Jank S, Eckardt KU, Grundmann F, Vitinius F, de Zwaan M, Bertram A, Erim Y: (2018) Psychosocial Variables Associated with Immunosuppressive Medication Non-Adherence after Renal Transplantation. Front Psychiatry. 2018;9():
Weber S, Dienemann T, Jacobi J, Eckardt KU, Weidemann A: (2018) Delayed graft function is associated with an increased rate of renal allograft rejection: A retrospective single center analysis. PLoS ONE. 2018;13(6):
Scheppach JB, Raff U, Toncar S, Ritter C, Klink T, Stoerk S, Wanner C, Schlieper G, Saritas T, Reinartz SD, Floege J, Janka R, Uder M, Schmieder RE, Eckardt KU, Schneider MP: (2018) Blood Pressure Pattern and Target Organ Damage in Patients With Chronic Kidney Disease Hypertension. 2018;72(4): 929-936
Schneider MP, Hilgers KF, Schmid M, Hübner S, Nadal J, Seitz D, Busch M, Haller H, Köttgen A, Kronenberg F, Baid-Agrawal S, Schlieper G, Schultheiss U, Sitter T, Sommerer C, Titze S, Meiselbach H, Wanner C, Eckardt KU, GCKD study Investigators: (2018) Blood pressure control in chronic kidney disease: A cross-sectional analysis from the German Chronic Kidney Disease (GCKD) study. PLoS ONE. 2018;13(8): e0202604
Schneider MP, Hilgers KF, Schmid M, Hübner S, Nadal J, Seitz D, Busch M, Haller H, Köttgen A, Kronenberg F, Baid-Agrawal S, Schlieper G, Schultheiss U, Sitter T, Sommerer C, Titze S, Meiselbach H, Wanner C, Eckardt KU, GCKD study Investigators: (2018) Correction: Blood pressure control in chronic kidney disease: A cross-sectional analysis from the German Chronic Kidney Disease (GCKD) study. PLoS ONE. 2018;13(9):
Kraus A, Peters DJM, Klanke B, Weidemann A, Willam C, Schley G, Kunzelmann K, Eckardt KU, Buchholz B: (2018) HIF-1α promotes cyst progression in a mouse model of autosomal dominant polycystic kidney disease. Kidney Int. 2018;94(5): 887-899
Teumer A, Chaker L, Groeneweg S, Li Y, Di Munno C, Barbieri C, Schultheiss UT, Traglia M, Ahluwalia TS, Akiyama M, Appel EVR, Arking DE, Arnold A, Astrup A, Beekman M, Beilby JP, Bekaert S, Boerwinkle E, Brown SJ, De Buyzere M, Campbell PJ, Ceresini G, Cerqueira C, Cucca F, Deary IJ, Deelen J, Eckardt KU, Ekici AB, Eriksson JG, Ferrrucci L, Fiers T, Fiorillo E, Ford I, Fox CS, Fuchsberger C, Galesloot TE, Gieger C, Gögele M, De Grandi A, Grarup N, Greiser KH, Haljas K, Hansen T, Harris SE, van Heemst D, den Heijer M, Hicks AA, den Hollander W, Homuth G, Hui J, Ikram MA, Ittermann T, Jensen RA, Jing J, Jukema JW, Kajantie E, Kamatani Y, Kasbohm E, Kaufman JM, Kiemeney LA, Kloppenburg M, Kronenberg F, Kubo M, Lahti J, Lapauw B, Li S, Liewald DCM, LifeLines Cohort Study , Lim EM, Linneberg A, Marina M, Mascalzoni D, Matsuda K, Medenwald D, Meisinger C, Meulenbelt I, De Meyer T, Meyer Zu Schwabedissen HE, Mikolajczyk R, Moed M, Netea-Maier RT, Nolte IM, Okada Y, Pala M, Pattaro C, Pedersen O, Petersmann A, Porcu E, Postmus I, Pramstaller PP, Psaty BM, Ramos YFM, Rawal R, Redmond P, Richards JB, Rietzschel ER, Rivadeneira F, Roef G, Rotter JI, Sala CF, Schlessinger D, Selvin E, Slagboom PE, Soranzo N, Sørensen TIA, Spector TD, Starr JM, Stott DJ, Taes Y, Taliun D, Tanaka T, Thuesen B, Tiller D, Toniolo D, Uitterlinden AG, Visser WE, Walsh JP, Wilson SG, Wolffenbuttel BHR, Yang Q, Zheng HF, Cappola A, Peeters RP, Naitza S, Völzke H, Sanna S, Köttgen A, Visser TJ, Medici M, Alizadeh BZ, Boezen HM, Franke L, van der Harst P, Navis G, Rots M, Snieder H, Swertz MA, Wijmenga C: (2018) Genome-wide analyses identify a role for SLC17A4 and AADAT in thyroid hormone regulation. Nat Commun. 2018;9(1):
Evans M, Grams ME, Sang Y, Astor BC, Blankestijn PJ, Brunskill NJ, Collins JF, Kalra PA, Kovesdy CP, Levin A, Mark PB, Moranne O, Rao P, Rios PG, Schneider MP, Shalev V, Zhang H, Chang AR, Gansevoort RT, Matsushita K, Zhang L, Eckardt KU, Hemmelgarn B, Wheeler DC: (2018) Risk Factors for Prognosis in Patients With Severely Decreased GFR. Kidney Int Rep. 2018;3(3): 625-637
Kopp C, Beyer C, Linz P, Dahlmann A, Hammon M, Jantsch J, Neubert P, Rosenhauer D, Müller DN, Cavallaro A, Eckardt KU, Schett G, Luft FC, Uder M, Distler JH, Titze J: (2017) Na+ deposition in the fibrotic skin of systemic sclerosis patients detected by 23Na-magnetic resonance imaging. Rheumatology (Oxford). 2017;56(4): 556-560
Schellinger IN, Cordasic N, Panesar J, Buchholz B, Jacobi J, Hartner A, Klanke B, Jakubiczka-Smorag J, Burzlaff N, Heinze E, Warnecke C, Raaz U, Willam C, Tsao PS, Eckardt KU, Amann K, Hilgers KF: (2017) Hypoxia inducible factor stabilization improves defective ischemia-induced angiogenesis in a rodent model of chronic kidney disease. Kidney Int. 2017;91(3): 616-627
Schneider MP, Raff U, Kopp C, Scheppach JB, Toncar S, Wanner C, Schlieper G, Saritas T, Floege J, Schmid M, Birukov A, Dahlmann A, Linz P, Janka R, Uder M, Schmieder RE, Titze JM, Eckardt KU: (2017) Skin Sodium Concentration Correlates with Left Ventricular Hypertrophy in CKD. J Am Soc Nephrol. 2017;28(6): 1867-1876
Macdougall IC, Bock AH, Carrera F, Eckardt KU, Gaillard C, Van Wyck D, Meier Y, Larroque S, Roger SD, FIND-CKD Study Investigators , Roger SD, Gilles A, Faull R, Toussaint ND, McMahon L, Suranyi M, Mudge D, Hutchison B, Irish A, Kerr P, Kulkarni H, Elder G, Jardine M, Lhotta K, Mayer G, Vanholder R, Maes BD, Evenepoel P, Debelle F, Jadoul M, Dratwa M, Macel I, Dunaj M, Kvapil M, Bucek P, Rehorova J, Hruby A, Honová V, Malanova L, Lucak M, Lecian D, Jirovec M, Vlasak J, Rychlik I, Surel S, Kamper AL, Ostergaard O, Steffensen GK, Chenine L, Choukroun G, Zaoui P, Wanner C, Backs W, Kraatz U, Dellanna F, Busch K, Marsen T, Seeger W, Woitas R, Obermueller N, Haak T, Lueders S, Pistrosch F, Mueller E, Mertens PR, Sutermer W, Grebe SO, Hafezi-Rachti S, Roeser S, Tsakiris D, Memmos D, Vlachakos D, Vargemezis V, Stefanidis I, Syrganis C, Alivanis P, Papadakis I, Papagalanis N, Andrikos A, Goumenos D, Siamopoulos K, Gouva C, Papadakis G, Boletis I, Tsimnadi-Spanoudaki M, Stamatiades D, Stamatelou K, Moutafis S, Locatelli F, Santoro A, Quarello F, Remuzzi G, Coppola S, Mortellaro RF, Icardi A, Colussi G, Grotta FD, Lombardi L, Gallieni M, Villa G, Grandaliano G, Gaillard C, Huisman S, Barendregt J, Gregoor PJ, Oien C, Rutkowski B, Malecki R, Nowicki M, Rutkowski P, Marczewski K, Mysliwiec M, Sydor A, Rysz J, Rydzewski A, Klinger M, Wnuk R, Kozminski P, Nocon A, Ciechanowski K, Correia P, Neves F, Barata J, Mircescu G, Voiculescu M, Gluhovschi G, Mota E, de Francisco AL, Torre A, Herreros A, Luño J, Gruss E, Martins J, Vallés M, Pascual J, Bárány P, Bock AH, Ambuehl PM, Erturk S, Arici M, Paydas S, Soypacaci Z, Camsari T, Ustundag S, Macdougall IC, Thomas ME, D'Souza RJ, Taylor JE, Pritchard NR, Jeffery R, Riley SG, Bhatnagar D, Bhandari S, Reaich D, Stevens PE, El Kossi M, Roe S, Camilleri B, Ahmed A, Khwaja A, Thompson B, Banerjee D, Nicholas J, Hutchison A, Borrows R: (2017) Renal function in patients with non-dialysis chronic kidney disease receiving intravenous ferric carboxymaltose: an analysis of the randomized FIND-CKD trial. BMC Nephrol. 2017;18(1): 24
Scheel J, Reber S, Stoessel L, Waldmann E, Jank S, Eckardt KU, Grundmann F, Vitinius F, de Zwaan M, Bertram A, Erim Y: (2017) Patient-reported non-adherence and immunosuppressant trough levels are associated with rejection after renal transplantation. BMC Nephrol. 2017;18(1): 107
Levin A, Tonelli M, Bonventre J, Coresh J, Donner JA, Fogo AB, Fox CS, Gansevoort RT, Heerspink HJL, Jardine M, Kasiske B, Köttgen A, Kretzler M, Levey AS, Luyckx VA, Mehta R, Moe O, Obrador G, Pannu N, Parikh CR, Perkovic V, Pollock C, Stenvinkel P, Tuttle KR, Wheeler DC, Eckardt KU, ISN Global Kidney Health Summit participants , Adu D, Agarwal SK, Alrukhaimi M, Anders HJ, Ashuntantang G, Basnet S, Bello AK, Chailimpamontree W, Correa-Rotter R, Craig J, Douthat WG, Feldman HI, Ganji MR, Garcia-Garcia G, Gharbi MB, Harris DC, Jha V, Johnson DW, Kazancioglu R, Langham R, Liu ZH, Massy ZA, Nangaku M, Nelson RG, O'Donoghue D, Okpechi I, Pecoits-Filho R, Powe NR, Remuzzi G, Roberts C, Rossert J, Solá L, Stengel B, M EKS, Suzuki Y, Tanaka T, Tatiyanupanwong S, Thomas B, Uhlig K, Walker R, White SL, Wiecek A, Yang CW: (2017) Global kidney health 2017 and beyond: a roadmap for closing gaps in care, research, and policy. Lancet. 2017;390(10105): 1888-1917
Charytan DM, Solomon SD, Ivanovich P, Remuzzi G, Cooper ME, McGill JB, Parving HH, Parfrey P, Singh AK, Burdmann EA, Levey AS, de Zeeuw D, Eckardt KU, McMurray JJV, Claggett B, Lewis EF, Pfeffer MA: (2017) ESRD After Heart Failure, Myocardial Infarction, or Stroke in Type 2 Diabetic Patients With CKD. Am J Kidney Dis. 2017;70(4): 522-531
Knaup KX, Guenther R, Stoeckert J, Monti JM, Eckardt KU, Wiesener MS: (2017) HIF is not essential for suppression of experimental tumor growth by mTOR inhibition. J Cancer. 2017;8(10): 1809-1817
Casadevall N, Dobronravov V, Eckardt KU, Erturk S, Martynyuk L, Schmitt S, Schaffar G, Rudy A, Krendyukov A, Ode M: (2017) Evaluation of the safety and immunogenicity of subcutaneous HX575 epoetin alfa in the treatment of anemia associated with chronic kidney disease in predialysis and dialysis patients?. Clin Nephrol. 2017;88(10): 190-197
Maier A, Wu H, Cordasic N, Oefner P, Dietel B, Thiele C, Weidemann A, Eckardt KU, Warnecke C: (2017) Hypoxia-inducible protein 2 Hig2/Hilpda mediates neutral lipid accumulation in macrophages and contributes to atherosclerosis in apolipoprotein E-deficient mice. FASEB J. 2017;31(11): 4971-4984
Matsushita K, Ballew SH, Coresh J, Arima H, Ärnlöv J, Cirillo M, Ebert N, Hiramoto JS, Kimm H, Shlipak MG, Visseren FLJ, Gansevoort RT, Kovesdy CP, Shalev V, Woodward M, Kronenberg F, Chronic Kidney Disease Prognosis Consortium , Chalmers J, Arima H, Perkovic V, Grams ME, Sang Y, Schaeffner E, Martus P, Levin A, Djurdjev O, Tang M, Heine G, Seiler S, Zawada A, Emrich I, Sarnak M, Katz R, Brenner H, Schöttker B, Rothenbacher D, Saum KU, Köttgen A, Schneider M, Eckardt KU, Green J, Kirchner HL, Chang AR, Black C, Marks A, Prescott G, Clark L, Fluck N, Jee SH, Mok Y, Chodick G, Shalev V, Wetzels JFM, Blankestijn PJ, van Zuilen AD, Bots M, Peralta C, Hiromoto J, Katz R, Sarnak M, Bottinger E, Nadkarni GN, Ellis SB, Nadukuru R, Kenealy T, Elley CR, Collins JF, Drury PL, Bakker SJ, Heerspink HJL, Jassal SK, Bergstrom J, Ix JH, Barrett-Connor E, Kalantar-Zadeh K, Carrero JJ, Gasparini A, Qureshi AR, Bárány P, Algra A, van der Graaf Y, Evans M, Segelmark M, Stendahl M, Schön S, Tangri N, Sud M, Naimark D, Lannfelt L, Larsson A, Hallan S, Levey AS, Chen J, Kwak L, Grams ME, Sang Y: (2017) Measures of chronic kidney disease and risk of incident peripheral artery disease: a collaborative meta-analysis of individual participant data. Lancet Diabetes Endocrinol. 2017;5(9): 718-728
Wunnenburger S, Schultheiss UT, Walz G, Hausknecht B, Ekici AB, Kronenberg F, Eckardt KU, Köttgen A, Wuttke M: (2017) Associations between genetic risk variants for kidney diseases and kidney disease etiology. Sci Rep. 2017;7(1): 13944
Macdougall IC, Bock AH, Carrera F, Eckardt KU, Gaillard C, Wyck DV, Meier Y, Larroque S, Perrin A, Roger SD: (2017) Erythropoietic response to oral iron in patients with nondialysis-dependent chronic kidney disease in the FIND-CKD trial?. Clin Nephrol. 2017;88(12): 301-310
Kopp C, Beyer C, Linz P, Dahlmann A, Hammon M, Jantsch J, Neubert P, Rosenhauer D, Müller DN, Cavallaro A, Eckardt KU, Schett G, Luft FC, Uder M, Distler JH, Titze J: (2017) Na+ deposition in the fibrotic skin of systemic sclerosis patients detected by 23Na-magnetic resonance imaging. Rheumatology (Oxford). 2017;56(4): 674
Coassin S, Erhart G, Weissensteiner H, de Araujo MEG, Lamina C, Schonherr S, Forer L, Haun M, Losso JL, Köttgen A, Schmidt K, Utermann G, Peters A, Gieger C, Strauch K, Finkenstedt A, Bale R, Zoller H, Paulweber B, Eckardt KU, Huttenhofer A, Huber LA, Kronenberg F: (2017) A novel but frequent variant in LPA KIV-2 is associated with a pronounced Lp(a) and cardiovascular risk reduction Eur Heart J. 2017;38(23): 1823-+
Levin A, Eckardt KU, Tonelli M: (2017) The Global Kidney Health Summit Outputs: details to guide the nephrology community along the road to global kidney health Kidney Int Suppl (2011). 2017;7(2): 61-62
Roger SD, Gaillard CA, Bock AH, Carrera F, Eckardt KU, Van Wyck DB, Cronin M, Meier Y, Larroque S, Macdougall IC, FIND-CKD Study Investigators: (2017) Safety of intravenous ferric carboxymaltose versus oral iron in patients with nondialysis-dependent CKD: an analysis of the 1-year FIND-CKD trial Nephrol Dial Transplant. 2017;32(9): 1530-1539
Sekula P, Li Y, Stanescu HC, Wuttke M, Ekici AB, Bockenhauer D, Walz G, Powis SH, Kielstein JT, Brenchley P, GCKD Investigators , Eckardt KU, Kronenberg F, Kleta R, Köttgen A, Eckardt KU, Titze S, Prokosch HU, Bärthlein B, Reis A, Ekici AB, Gefeller O, Hilgers KF, Hübner S, Avendano S, Becker-Grosspitsch D, Hauck N, Seuchter SA, Hausknecht B, Rittmeier M, Weigel A, Beck A, Ganslandt T, Knispel S, Dressel T, Malzer M, Floege J, Eitner F, Schlieper G, Findeisen K, Arweiler E, Ernst S, Unger M, Lipski S, Schaeffner E, Baid-Agrawal S, Petzold K, Schindler R, Köttgen A, Schultheiss U, Meder S, Mitsch E, Reinhard U, Walz G, Haller H, Lorenzen J, Kielstein JT, Otto P, Sommerer C, Föllinger C, Zeier M, Wolf G, Busch M, Paul K, Dittrich L, Sitter T, Hilge R, Blank C, Wanner C, Krane V, Schmiedeke D, Toncar S, Cavitt D, Schönowsky K, Börner-Klein A, Kronenberg F, Raschenberger J, Kollerits B, Forer L, Schönherr S, Weißensteiner H, Oefner P, Gronwald W, Zacharias H, Schmid M: (2017) Genetic risk variants for membranous nephropathy: extension of and association with other chronic kidney disease aetiologies. Nephrol Dial Transplant. 2017;32(2): 325-332
Zschiedrich S, Budde K, Nürnberger J, Wanner C, Sommerer C, Kunzendorf U, Banas B, Hoerl WH, Obermüller N, Arns W, Pavenstädt H, Gaedeke J, Lindner TH, Faerber L, Wimmer P, Stork R, Eckardt KU, Walz G: (2016) Secreted frizzled-related protein 4 predicts progression of autosomal dominant polycystic kidney disease. Nephrol Dial Transplant. 2016;31(2): 284-9
Kraus A, Schley G, Kunzelmann K, Schreiber R, Peters DJ, Stadler R, Eckardt KU, Buchholz B: (2016) Glucose promotes secretion-dependent renal cyst growth. J Mol Med. 2016;94(1): 107-17
Stenvinkel P, Gillespie IA, Tunks J, Addison J, Kronenberg F, Drueke TB, Marcelli D, Schernthaner G, Eckardt KU, Floege J, Froissart M, Anker SD, ARO Steering Committee: (2016) Inflammation Modifies the Paradoxical Association between Body Mass Index and Mortality in Hemodialysis Patients. J Am Soc Nephrol. 2016;27(5): 1479-86
Maxwell PH, Eckardt KU: (2016) HIF prolyl hydroxylase inhibitors for the treatment of renal anaemia and beyond. Nat Rev Nephrol. 2016;12(3): 157-68
Jacobi J, Beckmann S, Heller K, Hilgers KF, Apel H, Spriewald B, Eckardt KU, Amann KU: (2016) Deceased Donor Kidney Transplantation in the Eurotransplant Senior Program (ESP): A Single-Center Experience from 2008 to 2013. Ann Transplant. 2016;21(): 94-104
Heim C, Bernhardt W, Jalilova S, Wang Z, Motsch B, Ramsperger-Gleixner M, Burzlaff N, Weyand M, Eckardt KU, Ensminger SM: (2016) Prolyl-hydroxylase inhibitor activating hypoxia-inducible transcription factors reduce levels of transplant arteriosclerosis in a murine aortic allograft model. Interact Cardiovasc Thorac Surg. 2016;22(5): 561-70
Sagban TA, Regus S, Heller K, Jacobi J, Apel H, Keck B, Richterstetter M, Eckardt KU, Wullich B, Lang W: (2016) Results of Renal Transplantation on Alloplastic Arterial Grafts. Urol Int. 2016;96(2): 157-63
Mulay SR, Eberhard JN, Pfann V, Marschner JA, Darisipudi MN, Daniel C, Romoli S, Desai J, Grigorescu M, Kumar SV, Rathkolb B, Wolf E, Hrab? de Angelis M, Bäuerle T, Dietel B, Wagner CA, Amann K, Eckardt KU, Aronson PS, Anders HJ, Knauf F: (2016) Oxalate-induced chronic kidney disease with its uremic and cardiovascular complications in C57BL/6 mice. Am J Physiol Renal Physiol. 2016;310(8): F785-F795
Eckardt KU: (2016) Chronic Kidney Disease (Not) on the Agenda. Dtsch Arztebl Int. 2016;113(6): 83-4
Tangri N, Grams ME, Levey AS, Coresh J, Appel LJ, Astor BC, Chodick G, Collins AJ, Djurdjev O, Elley CR, Evans M, Garg AX, Hallan SI, Inker LA, Ito S, Jee SH, Kovesdy CP, Kronenberg F, Heerspink HJ, Marks A, Nadkarni GN, Navaneethan SD, Nelson RG, Titze S, Sarnak MJ, Stengel B, Woodward M, Iseki K, CKD Prognosis Consortium , Wright JT, Appel LJ, Greene T, Astor BC, Coresh J, Matsushita K, Grams ME, Sang Y, Levin A, Djurdjev O, Navaneethan SD, Nally JV, Schold JD, Wheeler DC, Emberson J, Townend JN, Landray MJ, Appel LJ, Feldman H, Hsu CY, Eckardt KU, Köttgen A, Kronenberg F, Titze S, Green J, Kirchner H, Perkins R, Chang AR, Black C, Marks A, Fluck N, Clark L, Prescott GJ, Ito S, Miyazaki M, Nakayama M, Yamada G, Hallan S, Aasarød K, Romundstad S, Smith DH, Thorp ML, Johnson ES, Collins AJ, Chen SC, Li S, Chodick G, Shalev V, Ash N, Shainberg B, Wetzels JF, Blankestijn PJ, van Zuilen AD, Sarnak MJ, Levey AS, Inker LA, Menon V, Kronenberg F, Kollerits B, Ritz E, Nadkarni GN, Bottinger EP, Ellis SB, Nadukuru R, Froissart M, Stengel B, Metzger M, Haymann JP, Houillier P, Flamant M, Elley C, Kenealy T, Moyes SA, Collins JF, Drury PL, Iseki K, Garg AX, McArthur E, Nesrallah G, Kim SJ, Nelson RG, Knowler WC, Warnock DG, Muntner P, Judd S, McClellan W, Gutierrez O, Heerspink HJ, Brenner BE, de Zeeuw D, Jee SH, Kimm H, Mok Y, Evans M, Stendahl M, Tangri N, Sud M, Naimark D, Kovesdy CP, Kalantar-Zadeh K, Coresh J, Gansevoort RT, Grams ME, de Jong PE, Iseki K, Levey AS, Matsushita K, Sarnak MJ, Stengel B, Warnock D, Woodward M, Ballew SH, Coresh J, Grams ME, Matsushita K, Sang Y, Woodward M: (2016) Multinational Assessment of Accuracy of Equations for Predicting Risk of Kidney Failure: A Meta-analysis. JAMA. 2016;315(2): 164-74
Macdougall IC, Bircher AJ, Eckardt KU, Obrador GT, Pollock CA, Stenvinkel P, Swinkels DW, Wanner C, Weiss G, Chertow GM, Conference Participants , Adamson JW, Akizawa T, Anker SD, Auerbach M, Bárány P, Besarab A, Bhandari S, Cabantchik I, Collins AJ, Coyne DW, de Francisco ÁL, Fishbane S, Gaillard CA, Ganz T, Goldsmith DJ, Hershko C, Jankowska EA, Johansen KL, Kalantar-Zadeh K, Kalra PA, Kasiske BL, Locatelli F, Ma?yszko J, Mayer G, McMahon LP, Mikhail A, Nemeth E, Pai AB, Parfrey PS, Pecoits-Filho R, Roger SD, Rostoker G, Rottembourg J, Singh AK, Slotki I, Spinowitz BS, Tarng DC, Tentori F, Toblli JE, Tsukamoto Y, Vaziri ND, Winkelmayer WC, Wheeler DC, Zakharova E: (2016) Iron management in chronic kidney disease: conclusions from a "Kidney Disease: Improving Global Outcomes" (KDIGO) Controversies Conference. Kidney Int. 2016;89(1): 28-39
Gansevoort RT, Arici M, Benzing T, Birn H, Capasso G, Covic A, Devuyst O, Drechsler C, Eckardt KU, Emma F, Knebelmann B, Le Meur Y, Massy ZA, Ong AC, Ortiz A, Schaefer F, Torra R, Vanholder R, Wi?cek A, Zoccali C, Van Biesen W: (2016) Recommendations for the use of tolvaptan in autosomal dominant polycystic kidney disease: a position statement on behalf of the ERA-EDTA Working Groups on Inherited Kidney Disorders and European Renal Best Practice. Nephrol Dial Transplant. 2016;31(3): 337-48
Buchholz B, Schley G, Eckardt KU: (2016) The impact of hypoxia on nephrogenesis. Curr Opin Nephrol Hypertens. 2016;25(3): 180-6
Anker SD, Gillespie IA, Eckardt KU, Kronenberg F, Richards S, Drueke TB, Stenvinkel P, Pisoni RL, Robinson BM, Marcelli D, Froissart M, Floege J, On behalf the ARO Steering Committee (collaborators): (2016) Development and validation of cardiovascular risk scores for haemodialysis patients. Int J Cardiol. 2016;216(): 68-77
Ermer T, Eckardt KU, Aronson PS, Knauf F: (2016) Oxalate, inflammasome, and progression of kidney disease. Curr Opin Nephrol Hypertens. 2016;25(4): 363-71
Abramowicz D, Hazzan M, Maggiore U, Peruzzi L, Cochat P, Oberbauer R, Haller MC, Van Biesen W, Descartes Working Group and the European Renal Best Practice (ERBP) Advisory Board , Abramowicz D, Maggiore U, Budde K, Dudley C, Hazzan M, Klinger M, Oberbauer R, Pascual J, Schwartz S, Viklicky O, Cannata J, Cochat P, Covic A, Delvecchio L, Eckardt KU, Fouque D, Fox J, Heimburger O, Jager K, Lindley E, Marti A, Nagler E, Oberbauer R, Spasovski G, Tattersall J, Van Biesen W, Vanholder R, Wanner C, Wheeler D, Withers W, Wiecek A, Zoccali C: (2016) Does pre-emptive transplantation versus post start of dialysis transplantation with a kidney from a living donor improve outcomes after transplantation? A systematic literature review and position statement by the Descartes Working Group and ERBP. Nephrol Dial Transplant. 2016;31(5): 691-7
Busch M, Nadal J, Schmid M, Paul K, Titze S, Hübner S, Köttgen A, Schultheiss UT, Baid-Agrawal S, Lorenzen J, Schlieper G, Sommerer C, Krane V, Hilge R, Kielstein JT, Kronenberg F, Wanner C, Eckardt KU, Wolf G, GCKD study Investigators , Schlieper G, Findeisen K, Arweiler E, Ernst S, Unger M, Floege J, Schaeffner E, Baid-Agrawal S, Petzold K, Schindler R, Titze S, Hilgers K, Hübner S, Avendano S, Becker-Grosspitsch D, Eckardt KU, Köttgen A, Schultheiss U, Meder S, Mitsch E, Reinhard U, Walz G, Lorenzen J, Kielstein J, Otto P, Haller H, Sommerer C, Föllinger C, Löschner T, Zeier M, Busch M, Paul K, Dittrich L, Wolf G, Sitter T, Hilge R, Blank C, Fischereder M, Krane V, Schmiedeke D, Toncar S, Cavitt D, Schönowsky K, Franz S, Wanner C, Eckardt KU, Titze S, Hausknecht B, Rittmeier M, Weigel A, Prokosch HU, Bärthlein B, Haberländer K, Beck A, Ganslandt T, Knispel S, Dressel T, Gefeller O, Malzer M, Nadal J, Schmid M, Reis A, Ekici A, Kronenberg F, Kollerits B, Weißensteiner H, Forer L, Schönherr S, Oefner P, Gronwald W: (2016) Glycaemic control and antidiabetic therapy in patients with diabetes mellitus and chronic kidney disease - cross-sectional data from the German Chronic Kidney Disease (GCKD) cohort. BMC Nephrol. 2016;17(1): 59
Gaillard CA, Bock AH, Carrera F, Eckardt KU, Van Wyck DB, Bansal SS, Cronin M, Meier Y, Larroque S, Roger SD, Macdougall IC: (2016) Hepcidin Response to Iron Therapy in Patients with Non-Dialysis Dependent CKD: An Analysis of the FIND-CKD Trial. PLoS ONE. 2016;11(6): e0157063
Dahlmann A, Kopp C, Linz P, Cavallaro A, Seuss H, Eckardt KU, Luft FC, Titze J, Uder M, Hammon M: (2016) Quantitative assessment of muscle injury by (23)Na magnetic resonance imaging. Springerplus. 2016;5(1): 661
de Francisco AL, Gillespie IA, Gioni I, Floege J, Kronenberg F, Marcelli D, Wheeler DC, Froissart M, Drueke TB, ARO Steering Committee Cllaborators , Aljama P, Anker S, Drueke TB, Eckardt KU, Floege J, de Francisco A, Kronenberg F, Macdougall IC, Malyszko J, Schernthaner G, Stenvinkel P, Wheeler DC, Molemans B, Fouqueray B, Canaud B: (2016) Anti-parathyroid treatment effectiveness and persistence in incident haemodialysis patients with secondary hyperparathyroidism. Nefrologia. 2016;36(2): 164-75
Reber S, Morawa E, Stößel L, Jank S, Vitinius F, Eckardt KU, Erim Y: (2016) Prevalence and Modifiable Determinants of Non-Adherence in Adult Kidney Transplant Recipients in a German Sample. Z Psychosom Med Psychother. 2016;62(3): 270-83
Mc Causland FR, Claggett B, Burdmann EA, Eckardt KU, Kewalramani R, Levey AS, McMurray JJ, Parfrey P, Remuzzi G, Singh AK, Solomon SD, Toto RD, Pfeffer MA: (2016) C-Reactive Protein and Risk of ESRD: Results From the Trial to Reduce Cardiovascular Events With Aranesp Therapy (TREAT). Am J Kidney Dis. 2016;68(6): 873-881
Vogl FC, Mehrl S, Heizinger L, Schlecht I, Zacharias HU, Ellmann L, Nürnberger N, Gronwald W, Leitzmann MF, Rossert J, Eckardt KU, Dettmer K, Oefner PJ, GCKD study Investigators: (2016) Evaluation of dilution and normalization strategies to correct for urinary output in HPLC-HRTOFMS metabolomics. Anal Bioanal Chem. 2016;408(29): 8483-8493
Dienemann T, Fujii N, Orlandi P, Nessel L, Furth SL, Hoy WE, Matsuo S, Mayer G, Methven S, Schaefer F, Schaeffner ES, Solá L, Stengel B, Wanner C, Zhang L, Levin A, Eckardt KU, Feldman HI: (2016) International Network of Chronic Kidney Disease cohort studies (iNET-CKD): a global network of chronic kidney disease cohorts. BMC Nephrol. 2016;17(1): 121
Heim C, Motsch B, Jalilova S, Bernhardt WM, Ramsperger-Gleixner M, Burzlaff N, Weyand M, Eckardt KU, Ensminger SM: (2016) Reduction of obliterative bronchiolitis (OB) by prolyl-hydroxylase-inhibitors activating hypoxia-inducible transcription factors in an experimental mouse model. Transpl Immunol. 2016;39(): 66-73
Kraus A, Grampp S, Goppelt-Struebe M, Schreiber R, Kunzelmann K, Peters DJ, Leipziger J, Schley G, Schödel J, Eckardt KU, Buchholz B: (2016) P2Y2R is a direct target of HIF-1? and mediates secretion-dependent cyst growth of renal cyst-forming epithelial cells. Purinergic Signal. 2016;12(4): 687-695
Grampp S, Platt JL, Lauer V, Salama R, Kranz F, Neumann VK, Wach S, Stöhr C, Hartmann A, Eckardt KU, Ratcliffe PJ, Mole DR, Schödel J: (2016) Genetic variation at the 8q24.21 renal cancer susceptibility locus affects HIF binding to a MYC enhancer Nat Commun. 2016;7(): 13183-
Scheel J, Reber S, Stossel L, Waldmann E, Jank S, Eckardt KU, Vitinius F, de Zwaan M, Erim Y: (2016) IMMUNOSUPPRESSANT SERUM LEVELS AND VARIABILITY, NON-ADHERENCE, AND LATE REJECTION IN RENAL TRANSPLANT RECIPIENTS Transpl Int. 2016;29 3(): 35-35
Erim Y, Pany N, Jank S, Eckardt KU: (2016) A PSYCHOTHERAPY MANUAL FOR THE OPTIMIZATION OF IMMUNOSUPPRESSANT ADHERENCE AFTER KIDNEY TRANSPLANTATION: RESULTS OF THE FEASIBILITY STUDY Transpl Int. 2016;29 3(): 49-49
Schieber K, Stossel L, Jank S, Reber S, Grundmann F, Lueker C, Vitinius F, Paslakis G, Eckardt KU, Erim Y: (2016) COGNITIVE FUNCTIONING IN RENAL TRANSPLANT RECIPIENTS: RESULTS ARE COMPARABLE TO NORMATIVE DATA, BUT SUBGROUP ANALYSIS REVEALED POSSIBLE RISK FACTORS Transpl Int. 2016;29 3(): 8-8
Weidemann A, Karpf F, Dienemann T, Birkner K, Jacobi J, Eckardt KU: (2016) Reduced Incidence of Rejection in AB0-incompatible Kidney Transplantation - Five Year Follow-Up in a Single Center. Am J Transplant. 2016;16 3(): 445-445
Dienemann T, Weber S, Jacobi J, Eckardt KU, Weidemann A: (2016) Delayed Graft Function Is an Independent Risk Factor for Renal Allograft Rejection. Am J Transplant. 2016;16 3(): 497-497
Schneider M, Mieth M, Titze S, Kronenberg F, Li Y, Maas R, Eckardt KU: (2016) ASYMMETRIC DIMETHLYARGININE DIRECTLY PROMOTES CHRONIC KIDNEY DISEASE PROGRESSION: EVIDENCE FROM A MENDELIAN RANDOMIZATION APPROACH IN THE GCKD STUDY Atherosclerosis. 2016;252(): E256-E257
Roger S, Bock AH, Carrera F, Eckardt KU, Gaillard CA, Van Wyck DB, Meier Y, Larroque S, Macdougall IC: (2016) THE SAFETY OF INTRAVENOUS (IV) FERRIC CARBOXYMALTOSE (FCM) IN PATIENTS WITH NON-DIALYSIS DEPENDENT CKD (ND-CKD): 1-YEAR RESULTS FROM THE FIND-CKD TRIAL Nephrol Dial Transplant. 2016;31 1(): 15-16
Macdougall I, Bock AH, Carrera F, Eckardt KU, Gaillard CA, Van Wyck DB, Meier Y, Larroque S, Roger SD: (2016) A MODEL TO PREDICT HAEMATOPOIETIC NON-RESPONSE TO ORAL IRON IN PATIENTS WITH NON-DIALYSIS DEPENDENT CKD (ND-CKD): AN ANALYSIS FROM THE FIND-CKD TRIAL Nephrol Dial Transplant. 2016;31 1(): 193-194
Casadevall N, Dobronravov V, Eckardt KU, Erturk S, Martynyuk L, Schmitt S, Ode M, Schaffar G, Rudy A: (2016) EVALUATION OF THE SAFETY AND IMMUNOGENICITY OF SUBCUTANEOUS (SC) HX575 EPOETIN ALFA IN THE TREATMENT OF ANAEMIA ASSOCIATED WITH CKD Nephrol Dial Transplant. 2016;31 1(): 194-194
Vogler M, Zieseniss A, Hesse AR, Levent E, Tiburcy M, Heinze E, Burzlaff N, Schley G, Eckardt KU, Willam C, Katschinski D: (2015) Pre- and post-conditional inhibition of prolyl-4-hydroxylase domain enzymes protects the heart from an ischemic insult Acta Physiol (Oxf). 2015;213 699(): 79-80
Zatyka M, da Silva NF, Clifford SC, Morris MR, Wiesener MS, Eckardt KU: (2015) Identification of Cyclin D1 and OtherNovel Targets for the von Hippel-Lindau Tumor Suppressor Gene by Expression Array Analysis and Investigation of Cyclin D1 Genotype as a Modifier in von Hippel-Lindau Disease (vol 62, pg 3803, 2002) Cancer Res. 2015;75(18): 3993-3993
Weiss J, Bein T, Briegel J, Eckardt KU, Gerresheim G, Grammenos D, Lang C, Niess C, Zeman F, Breidenbach T: (2015) IS THERE A CORRELATION BETWEEN ACCEPTANCE OF THE CONCEPT OF BRAIN DEATH AND THE WILLINGNESS TO DONATE OR RECEIVE ORGANS IN MEDICAL PROFESSIONALS IN GERMANY? Transpl Int. 2015;28 4(): 75-75
Weiss J, Bein T, Briegel J, Eckardt KU, Gerresheim G, Grammenos D, Lang C, Niess C, Zeman F, Breidenbach T: (2015) INFLUENCE OF MEDIA COVERAGE ON ATTITUDES OF MEDICAL PROFESSIONALS TOWARDS THE INSTITUTIONS RESPONSIBLE FOR ORGAN DONATION, ALLOCATION AND TRANSPLANTATION Transpl Int. 2015;28 4(): 76-76
Darisipudi M, Roessler S, Asplin J, Granja I, Eckardt KU, Flavell R, Aronson P, Knauf F: (2015) INTERLEUKIN-1BETA-DEFICIENCY PROTECTS FROM CHRONIC OXALATE NEPHROPATHY AND MORTALITY Nephrol Dial Transplant. 2015;30 3(): -
Macdougall IC, Bock AH, Carrera F, Eckardt KU, Gaillard CA, Van Wyck DB, Bansal SS, Roubert B, Nolen JG, Roger SD: (2015) HEPCIDIN RESPONSE TO IRON THERAPY IN PATIENTS WITH NON-DIALYSIS CKD: AN ANALYSIS OF THE FIND-CKD TRIAL Nephrol Dial Transplant. 2015;30 3(): -
Schneider M, Hubner S, Titze S, Schmid M, Nadal J, Schlieper G, Busch M, Baid-Agrawal S, Wanner C, Kronenberg F, Eckardt KU: (2015) IMPLEMENTATION OF THE KDIGO GUIDELINE ON LIPID MANAGEMENT WOULD REQUIRE SUBSTANTIAL INCREASE IN STATIN PRESCRIPTION RATES: AN ANALYSIS FROM THE GERMAN CHRONIC KIDNEY DISEASE(GCKD) COHORT Nephrol Dial Transplant. 2015;30 3(): -
Schieber K, Gaag S, Heller K, Eckardt KU, Erim Y: (2015) FOSTERING LIVING ORGAN DONATION: NEEDS AND SUGGESTIONS REPORTED BY LIVING KIDNEY DONORS Transpl Int. 2015;28 2(): 21-21
Dahlmann A, Dörfelt K, Eicher F, Linz P, Kopp C, Mössinger I, Horn S, Büschges-Seraphin B, Wabel P, Hammon M, Cavallaro A, Eckardt KU, Kotanko P, Levin NW, Johannes B, Uder M, Luft FC, Müller DN, Titze JM: (2015) Magnetic resonance-determined sodium removal from tissue stores in hemodialysis patients. Kidney Int. 2015;87(2): 434-41
Titze S, Schmid M, Köttgen A, Busch M, Floege J, Wanner C, Kronenberg F, Eckardt KU, for the GCKD Study Investigators: (2015) Disease burden and risk profile in referred patients with moderate chronic kidney disease: composition of the German Chronic Kidney Disease (GCKD) cohort. Nephrol Dial Transplant. 2015;30(3): 441-51
Jing J, Kielstein JT, Schultheiss UT, Sitter T, Titze SI, Schaeffner ES, McAdams-DeMarco M, Kronenberg F, Eckardt KU, Köttgen A, for the GCKD Study Investigators: (2015) Prevalence and correlates of gout in a large cohort of patients with chronic kidney disease: the German Chronic Kidney Disease (GCKD) study. Nephrol Dial Transplant. 2015;30(4): 613-21
Kalucka J, Schley G, Georgescu A, Klanke B, Rössler S, Baumgartl J, Velden J, Amann K, Willam C, Johnson RS, Eckardt KU, Weidemann A: (2015) Kidney injury is independent of endothelial HIF-1?. J Mol Med. 2015;93(8): 891-904
Floege J, Gillespie IA, Kronenberg F, Anker SD, Gioni I, Richards S, Pisoni RL, Robinson BM, Marcelli D, Froissart M, Eckardt KU: (2015) Development and validation of a predictive mortality risk score from a European hemodialysis cohort. Kidney Int. 2015;87(5): 996-1008
Eckardt KU, Alper SL, Antignac C, Bleyer AJ, Chauveau D, Dahan K, Deltas C, Hosking A, Kmoch S, Rampoldi L, Wiesener M, Wolf MT, Devuyst O: (2015) Autosomal dominant tubulointerstitial kidney disease: diagnosis, classification, and management-A KDIGO consensus report. Kidney Int. 2015;88(4): 676-83
Eckardt KU, Gillespie IA, Kronenberg F, Richards S, Stenvinkel P, Anker SD, Wheeler DC, de Francisco AL, Marcelli D, Froissart M, Floege J, ARO Steering Committee , Aljama P, Anker S, Drueke TB, Eckardt KU, Floege J, de Francisco A, Kronenberg F, Macdougall IC, Malyszko J, Schernthaner G, Stenvinkel P, Wheeler DC, Molemans B, Canaud B: (2015) High cardiovascular event rates occur within the first weeks of starting hemodialysis. Kidney Int. 2015;88(5): 1117-25
Goldsmith D, Covic A, Vervloet M, Cozzolino M, Nistor I, Chronic Kidney Disease-Mineral Bone Disease (CKD-MBD) working group and the European Renal Best Practice (ERBP) advisory board , Chronic Kidney Disease-Mineral Bone Disease CKD-MBD working group and the European Renal Best Practice ERBP advisory board , Cozzolino M, Vervloet M, Brandenburg V, Bover J, Covic A, Evenepoel P, Goldsmith D, Massy Z, Mazzaferro S, Urena-Torres P, Abramowicz D, Bolignano D, Cannata Andia G, Cochat P, Covic A, Delvecchio L, Drechsler C, Eckardt KU, Fouque D, Fox J, Haller M, Heimburger O, Jager KJ, Lindley E, Marti Monros AM, Nagler E, Oberbauer R, Spasovski G, Tattersall J, Van Biesen W, Vander Veer S, Vanholder R, Wanner C, Wheeler D, Whithers W, Wiecek A, Zoccali C: (2015) Should patients with CKD stage 5D and biochemical evidence of secondary hyperparathyroidism be prescribed calcimimetic therapy? An ERA-EDTA position statement. Nephrol Dial Transplant. 2015;30(5): 698-700
Beck H, Titze SI, Hübner S, Busch M, Schlieper G, Schultheiss UT, Wanner C, Kronenberg F, Krane V, Eckardt KU, Köttgen A, GCKD Investigators: (2015) Heart Failure in a Cohort of Patients with Chronic Kidney Disease: The GCKD Study. PLoS ONE. 2015;10(4): e0122552
Vogler M, Zieseniss A, Hesse AR, Levent E, Tiburcy M, Heinze E, Burzlaff N, Schley G, Eckardt KU, Willam C, Katschinski DM: (2015) Pre- and post-conditional inhibition of prolyl-4-hydroxylase domain enzymes protects the heart from an ischemic insult. Pflugers Arch. 2015;467(10): 2141-9
Gillespie IA, Macdougall IC, Richards S, Jones V, Marcelli D, Froissart M, Eckardt KU, ARO Steering Committee: (2015) Factors precipitating erythropoiesis-stimulating agent responsiveness in a European haemodialysis cohort: case-crossover study. Pharmacoepidemiol Drug Saf. 2015;24(4): 414-26
Zacharias HU, Hochrein J, Vogl FC, Schley G, Mayer F, Jeleazcov C, Eckardt KU, Willam C, Oefner PJ, Gronwald W: (2015) Identification of Plasma Metabolites Prognostic of Acute Kidney Injury after Cardiac Surgery with Cardiopulmonary Bypass. J Proteome Res. 2015;14(7): 2897-905
Lewis EF, Claggett B, Parfrey PS, Burdmann EA, McMurray JJ, Solomon SD, Levey AS, Ivanovich P, Eckardt KU, Kewalramani R, Toto R, Pfeffer MA: (2015) Race and ethnicity influences on cardiovascular and renal events in patients with diabetes mellitus. Am Heart J. 2015;170(2): 322-329.e4
Raschenberger J, Kollerits B, Titze S, Köttgen A, Bärthlein B, Ekici AB, Forer L, Schönherr S, Weissensteiner H, Haun M, Wanner C, Eckardt KU, Kronenberg F, GCKD study Investigators: (2015) Association of relative telomere length with cardiovascular disease in a large chronic kidney disease cohort: The GCKD study. Atherosclerosis. 2015;242(2): 529-34
Lerchl K, Rakova N, Dahlmann A, Rauh M, Goller U, Basner M, Dinges DF, Beck L, Agureev A, Larina I, Baranov V, Morukov B, Eckardt KU, Vassilieva G, Wabel P, Vienken J, Kirsch K, Johannes B, Krannich A, Luft FC, Titze J: (2015) Agreement Between 24-Hour Salt Ingestion and Sodium Excretion in a Controlled Environment. Hypertension. 2015;66(4): 850-7
Jobst-Schwan T, Pannes A, Schlingmann KP, Eckardt KU, Beck BB, Wiesener MS: (2015) Discordant Clinical Course of Vitamin-D-Hydroxylase (CYP24A1) Associated Hypercalcemia in Two Adult Brothers With Nephrocalcinosis. Kidney Blood Press Res. 2015;40(5): 443-51
Schley G, Scholz H, Kraus A, Hackenbeck T, Klanke B, Willam C, Wiesener MS, Heinze E, Burzlaff N, Eckardt KU, Buchholz B: (2015) Hypoxia inhibits nephrogenesis through paracrine Vegfa despite the ability to enhance tubulogenesis. Kidney Int. 2015;88(6): 1283-1292
Schneider MP, Hübner S, Titze SI, Schmid M, Nadal J, Schlieper G, Busch M, Baid-Agrawal S, Krane V, Wanner C, Kronenberg F, Eckardt KU: (2015) Implementation of the KDIGO guideline on lipid management requires a substantial increase in statin prescription rates. Kidney Int. 2015;88(6): 1411-1418
Forschbach V, Goppelt-Struebe M, Kunzelmann K, Schreiber R, Piedagnel R, Kraus A, Eckardt KU, Buchholz B: (2015) Anoctamin 6 is localized in the primary cilium of renal tubular cells and is involved in apoptosis-dependent cyst lumen formation. Cell Death Dis. 2015;6(): e1899
Raschenberger J, Kollerits B, Titze S, Köttgen A, Bärthlein B, Ekici AB, Forer L, Schönherr S, Weissensteiner H, Haun M, Wanner C, Eckardt KU, Kronenberg F, GCKD study Investigators: (2015) Do telomeres have a higher plasticity than thought? Results from the German Chronic Kidney Disease (GCKD) study as a high-risk population. Exp Gerontol. 2015;72(): 162-6
Chapman AB, Devuyst O, Eckardt KU, Gansevoort RT, Harris T, Horie S, Kasiske BL, Odland D, Pei Y, Perrone RD, Pirson Y, Schrier RW, Torra R, Torres VE, Watnick T, Wheeler DC, Conference Participants , Ahn C, Alam A, Aussilhou B, Bae KT, Bennett WM, Bergmann C, Bichet DG, Budde K, Chauveau D, Cowley B, de Coninck B, Dell KM, Drenth JP, Ecder T, Emma F, Férec C, Flamion B, Galletti F, Gitomer B, Grantham JJ, Harr N, Harris PC, Higashihara E, Hodouchi E, Hogan MC, Jha V, Korst U, Lagrafeuil C, Martin RS, Mrug M, Obrador GT, Ong AC, Onuchic LF, Sternfeld L, Rangan GK, Sandford R, Serra AL, Steinman TI, Strandgaard S, Walz G, Winearls CG, Winston KY: (2015) Autosomal-dominant polycystic kidney disease (ADPKD): executive summary from a Kidney Disease: Improving Global Outcomes (KDIGO) Controversies Conference. Kidney Int. 2015;88(1): 17-27
Pfau A, Eckardt KU, Knauf F: (2015) [Diagnosis and treatment of nephrolithiasis : What is established?]. Internist (Berl). 2015;56(12): 1361-8
Müller HH, Englbrecht M, Wiesener MS, Titze S, Heller K, Groemer TW, Schett G, Eckardt KU, Kornhuber J, Maler JM: (2015) Depression, Anxiety, Resilience and Coping Pre and Post Kidney Transplantation - Initial Findings from the Psychiatric Impairments in Kidney Transplantation (PI-KT)-Study. PLoS ONE. 2015;10(11): e0140706
Rauen T, Eitner F, Fitzner C, Sommerer C, Zeier M, Otte B, Panzer U, Peters H, Benck U, Mertens PR, Kuhlmann U, Witzke O, Gross O, Vielhauer V, Mann JF, Hilgers RD, Floege J, STOP-IgAN Investigators , Floege J, Eitner F, Rauen T, Moeller MJ, Michaelis A, Weihprecht H, Baatz E, Söllner S, Peters H, Budde K, Markmann D, Elitok S, Bieringer M, Schindler R, Frei U, Canaan-Kühl S, Erley C, Schlieps K, Kuhlmann U, Zandvoort F, Bodemann ML, Hohenstein B, Hugo C, Palm C, Fleischer A, Hilgers K, Eckardt KU, Jank S, Witzke O, Kirchmeyer R, Gross O, Müller GA, Weber F, Birk HW, Feustel A, Jeßen S, Stahl RA, Panzer U, Kinzler E, Haller H, Bertram A, Bahlmann E, Zeier M, Sommerer C, Foellinger C, Wolf G, Busch M, Rüster C, Rath T, Ziefle S, Weik S, Benzing T, Bastek S, Kisner T, Mertens PR, Bosselmann HP, Piehler C, Westphalen S, Koepke S, Benck U, Göttmann U, Langhäuser B, Hoyer J, Maier T, Kortus-Goetze B, Vielhauer V, Fischereder M, Vilsmaier F, Sarkar O, Engelhardt S, Mann JF, Stefanidou M, Otte B, Pavenstädt H, George B, Banas B, Böger A, Emmer T, Weiner SM, Jochum E, Kiefer C, Heyne N, Artunc F, Georges G, Petermann A, Reichel H, Krumme B, Mettang T, Hirschberg M, Wanner C, Metzger T, Irmler-Mercier E: (2015) Intensive Supportive Care plus Immunosuppression in IgA Nephropathy. N Engl J Med. 2015;373(23): 2225-36
Schley G, Köberle C, Manuilova E, Rutz S, Forster C, Weyand M, Formentini I, Kientsch-Engel R, Eckardt KU, Willam C: (2015) Comparison of Plasma and Urine Biomarker Performance in Acute Kidney Injury. PLoS ONE. 2015;10(12): e0145042
Beck H, Titze SI, Hübner S, Busch M, Schlieper G, Schultheiss UT, Wanner C, Kronenberg F, Krane V, Eckardt KU, Köttgen A, GCKD Investigators: (2015) Correction: Heart Failure in a Cohort of Patients with Chronic Kidney Disease: The GCKD Study. PLoS ONE. 2015;10(6): e0131034
Macdougall IC, Bock A, Carrera F, Eckardt KU, Gaillard C, Van Wyck D, Roubert B, Cushway T, Roger SD, FIND-CKD Study Investigators: (2014) The FIND-CKD study--a randomized controlled trial of intravenous iron versus oral iron in non-dialysis chronic kidney disease patients: background and rationale. Nephrol Dial Transplant. 2014;29(4): 843-50
Grammenos D, Bein T, Briegel J, Eckardt KU, Gerresheim G, Lang C, Nieß C, Zeman F, Breidenbach T: (2014) [Attitudes of medical staff potentially participating in the organ donation process towards organ donation and transplantation in Bavaria]. Dtsch Med Wochenschr. 2014;139(24): 1289-94
Ekici AB, Hackenbeck T, Morinière V, Pannes A, Buettner M, Uebe S, Janka R, Wiesener A, Hermann I, Grupp S, Hornberger M, Huber TB, Isbel N, Mangos G, McGinn S, Soreth-Rieke D, Beck BB, Uder M, Amann K, Antignac C, Reis A, Eckardt KU, Wiesener MS: (2014) Renal fibrosis is the common feature of autosomal dominant tubulointerstitial kidney diseases caused by mutations in mucin 1 or uromodulin. Kidney Int. 2014;86(3): 589-99
Jacobi J, Rebhan D, Heller K, Velden J, Hilgers KF, Wullich B, Eckardt KU, Amann KU: (2014) Donor acute kidney injury and short-term graft outcome in renal transplantation. Clin Transplant. 2014;28(10): 1131-41
Joost R, Dörje F, Schwitulla J, Eckardt KU, Hugo C: (2014) Intensified pharmaceutical care is improving immunosuppressive medication adherence in kidney transplant recipients during the first post-transplant year: a quasi-experimental study. Nephrol Dial Transplant. 2014;29(8): 1597-607
Macdougall IC, Bock AH, Carrera F, Eckardt KU, Gaillard C, Van Wyck D, Roubert B, Nolen JG, Roger SD, on behalf of the FIND-CKD Study Investigators: (2014) FIND-CKD: a randomized trial of intravenous ferric carboxymaltose versus oral iron in patients with chronic kidney disease and iron deficiency anaemia. Nephrol Dial Transplant. 2014;29(11): 2075-84
Spithoven EM, Kramer A, Meijer E, Orskov B, Wanner C, Abad JM, Aresté N, Alonso de la Torre R, Caskey F, Couchoud C, Finne P, Heaf J, Hoitsma A, de Meester J, Pascual J, Postorino M, Ravani P, Zurriaga O, Jager KJ, Gansevoort RT, ERA-EDTA Registry , EuroCYST Consortium , WGIKD , ERA-EDTA Registry , de Los Ángeles García Bazaga M, Metcalfe W, Rodrigo E, Quirós JR, Budde K, Devuyst O, Ecder T, Eckardt KU, Gansevoort RT, Köttgen A, Ong AC, Petzold K, Pirson Y, Remuzzi G, Torra R, Sandford RN, Serra AL, Tesar V, Walz G, Wüthrich RP, Antignac C, Bindels R, Chauveau D, Devuyst O, Emma F, Gansevoort RT, Maxwell PH, Ong AC, Remuzzi G, Ronco P, Schaefer F: (2014) Renal replacement therapy for autosomal dominant polycystic kidney disease (ADPKD) in Europe: prevalence and survival-an analysis of data from the ERA-EDTA Registry. Nephrol Dial Transplant. 2014;29 Suppl 4(): iv15-iv25
Ludwig G, Dobe-Tauchert P, Nonnast-Daniel B, Stiefel F, de Jonge P, Lobo E, Richter R, Eckardt KU, Hohenberger W, Weyand M, Söllner W: (2014) Assessing psychosocial vulnerability and care needs of pretransplant patients by means of the INTERMED. Z Psychosom Med Psychother. 2014;60(2): 190-203
Spithoven EM, Kramer A, Meijer E, Orskov B, Wanner C, Caskey F, Collart F, Finne P, Fogarty DG, Groothoff JW, Hoitsma A, Nogier MB, Postorino M, Ravani P, Zurriaga O, Jager KJ, Gansevoort RT, ERA-EDTA Registry , EuroCYST Consortium , WGIKD , EuroCYST Consortium , WGIKD , Aresté N, Arias M, Couchoud C, Budde K, Chauveau D, Devuyst O, Ecder T, Eckardt KU, Gansevoort RT, Köttgen A, Ong AC, Petzold K, Pirson Y, Remuzzi G, Torra R, Sandford RN, Serra AL, Tesar V, Walz G, Wüthrich RP, Antignac C, Bindels R, Chauveau D, Devuyst O, Emma F, Gansevoort RT, Maxwell PH, Ong AC, Remuzzi G, Ronco P, Schaefer F: (2014) Analysis of data from the ERA-EDTA Registry indicates that conventional treatments for chronic kidney disease do not reduce the need for renal replacement therapy in autosomal dominant polycystic kidney disease. Kidney Int. 2014;86(6): 1244-52
Rakova N, Lerch K, Dahlmann A, Rauh M, Goller U, Basner M, Dinges DF, Beck L, Agureev A, Larina I, Baranov V, Morukov B, Eckardt KU, Vassilieva G, Wabel P, Vienken J, Kirsch K, Johannes B, Luft FC, Titze J: (2014) Salt Intake, Drinking Behavior, And The Body Corporate Hypertension. 2014;64 1(): -
Petzold K, Gansevoort RT, Ong ACM, Devuyst O, Rotar L, Eckardt KU, Köttgen A, Pirson Y, Remuzzi G, Sandford R, Tesar V, Ecder T, Chaveau D, Torra R, Budde K, Le Meur Y, Wüthrich RP, Serra AL: (2014) Building a network of ADPKD reference centres across Europe: the EuroCYST initiative Nephrol Dial Transplant. 2014;29 4(): 26-32
Petzold K, Gansevoort RT, Ong ACM, Devuyst O, Rotar L, Eckardt KU, Köttgen A, Pirson Y, Remuzzi G, Sandford R, Tesar V, Ecder T, Chaveau D, Torra R, Budde K, Le Meur Y, Wüthrich RP, Serra AL: (2014) Building a network of ADPKD reference centres across Europe: the EuroCYST initiative (vol 29, pg 26, 2014) Nephrol Dial Transplant. 2014;29(12): 2353-2353
Heisterkamp M, Titze S, Lorenzen J, Eckardt KU, Koettgen A, Kielstein JT: (2014) FREQUENCY AND DOSING OF URIC ACID LOWERING THERAPY IN PATIENTS WITH CKD 3-BASELINE DATA OF THE GERMAN CHRONIC KIDNEY DISEASE COHORT Nephrol Dial Transplant. 2014;29 3(): 114-114
Macdougall ID, Bock A, Carrera F, Eckardt KU, Gaillard C, Van Wyck D, Roubert B, Nolen J, Roger SD: (2014) INTRAVENOUS FERRIC CARBOXYMALTOSE VS ORAL IRON IN ANAEMIC PATIENTS WITH NON-DIALYSIS DEPENDENT CHRONIC KIDNEY DISEASE AND IRON DEFICIENCY: RESULTS OF THE RANDOMISED FIND-CKD STUDY Nephrol Dial Transplant. 2014;29 3(): 21-21
Roger SD, Bock A, Carrera F, Eckardt KU, Gaillard C, Van Wyck D, Roubert B, Nolen J, Macdougall C: (2014) IV FERRIC CARBOXYMALTOSE (FCM) IS A CONVENIENT AND WELL-TOLERATED FIRST-LINE THERAPY FOR THE TREATMENT OF ANAEMIA IN PATIENTS WITH IRON DEFICIENCY AND NON-DIALYSIS DEPENDENT CHRONIC KIDNEY DISEASE (ND-CKD): RESULTS OF THE RANDOMISED FIND-CKD STUDY Nephrol Dial Transplant. 2014;29 3(): 21-21
Grampp S, Goppelt-Strübe M, Eckardt KU, Schödel J: (2014) ANALYSES OF HYPOXIA INDUCIBLE TRANSCRIPTION FACTOR DNA-BINDING AND HYPOXIC GENE REGULATION IN PRIMARY HUMAN RENAL TUBULAR CELLS Nephrol Dial Transplant. 2014;29 3(): 330-330
Breidenbach T, Bein T, Briegel J, Eckardt KU, Gerresheim G, Lang C, Niess C, Zeman F, Grammenos D: (2014) ORGAN DONATION AND TRANSPLANTATION-ATTIDUDES OF MEDICAL PROFESSIONALS INVOLVED Transpl Int. 2014;27 3(): 25-25
Weiss J, Bein T, Briegel J, Eckardt KU, Gerresheim G, Grammenos D, Lang C, Niess C, Zeman F, Breidenbach T: (2014) THE CARE OF ORGAN DONORS - PERCEIVED STRESS OF MEDICAL PERSONNEL Transpl Int. 2014;27 3(): 35-35
Knaup KX, Monti J, Hackenbeck T, Jobst-Schwan T, Klanke B, Schietke RE, Wacker I, Behrens J, Amann K, Eckardt KU, Warnecke C, Wiesener MS: (2014) Hypoxia regulates the sperm associated antigen 4 (SPAG4) via HIF, which is expressed in renal clear cell carcinoma and promotes migration and invasion in vitro. Mol Carcinog. 2014;53(12): 970-8
Buchholz B, Schley G, Faria D, Kroening S, Willam C, Schreiber R, Klanke B, Burzlaff N, Jantsch J, Kunzelmann K, Eckardt KU: (2014) Hypoxia-Inducible Factor-1? Causes Renal Cyst Expansion through Calcium-Activated Chloride Secretion. J Am Soc Nephrol. 2014;25(3): 465-74
Buchholz B, Faria D, Schley G, Schreiber R, Eckardt KU, Kunzelmann K: (2014) Anoctamin 1 induces calcium-activated chloride secretion and proliferation of renal cyst-forming epithelial cells. Kidney Int. 2014;85(5): 1058-67
Paul K, Kretzschmar D, Yilmaz A, Bärthlein B, Titze S, Wolf G, Busch M, GCKD-Study Investigators , Eitner F, Schlieper G, Findeisen K, Arweiler E, Ernst S, Unger M, Floege J, Schaeffner E, Baid-Agrawal S, Petzold K, Schindler R, Hilgers KF, Hübner S, Avendano S, Becker-Grosspietsch D, Köttgen A, Schultheiss U, Meder S, Mitsch E, Walz G, Lorenzen J, Kielstein JT, Otto P, Haller H, Sommerer C, Föllinger C, Löschner T, Zeier M, Busch M, Paul K, Dittrich L, Wolf G, Sitter T, Hilge R, Blank C, Krane V, Schmiedeke D, Toncar S, Cavitt D, Wanner C, Franz S, Eckardt KU, Titze S, Hauck N, Seuchter SA, Hausknecht B, Rittmeier M, Weigel A, Prokosch HU, Bärthlein B, Haberländer K, Beck A, Ganslandt T, Stefan S, Knispel S, Dressel T, Gefeller O, Schmid M, Malzer M, Reis A, Ekici AB, Kronenberg F, Kollerits B, Weißensteiner H, Forer L, Schönherr S, Oefner P, Gronwald W: (2013) Circulating dendritic cell precursors in chronic kidney disease: a cross-sectional study. BMC Nephrol. 2013;14(): 274
Nangaku M, Rosenberger C, Heyman SN, Eckardt KU: (2013) Regulation of hypoxia-inducible factor in kidney disease. Clin Exp Pharmacol Physiol. 2013;40(2): 148-57
Kopp C, Linz P, Dahlmann A, Hammon M, Jantsch J, Muller DN, Schmieder RE, Cavallaro A, Eckardt KU, Uder M, Luft FC, Titze J: (2013) 23Na Magnetic Resonance Imaging-Determined Tissue Sodium in Healthy Subjects and Hypertensive Patients. Hypertension. 2013;61(3): 635-40
Rakova N, Jüttner K, Dahlmann A, Schröder A, Linz P, Kopp C, Rauh M, Goller U, Beck L, Agureev A, Vassilieva G, Lenkova L, Johannes B, Wabel P, Moissl U, Vienken J, Gerzer R, Eckardt KU, Muller DN, Kirsch K, Morukov B, Luft FC, Titze J: (2013) Long-term space flight simulation reveals infradian rhythmicity in human Na(+) balance. Cell Metab. 2013;17(1): 125-31
Kurt B, Paliege A, Willam C, Schwarzensteiner I, Schucht K, Neymeyer H, Sequeira-Lopez ML, Bachmann S, Gomez RA, Eckardt KU, Kurtz A: (2013) Deletion of von Hippel-Lindau protein converts renin-producing cells into erythropoietin-producing cells. J Am Soc Nephrol. 2013;24(3): 433-44
Eckardt KU: (2013) Anaemia: The safety and efficacy of peginesatide in patients with CKD. Nat Rev Nephrol. 2013;9(4): 192-3
Jobst-Schwan T, Knaup KX, Nielsen R, Hackenbeck T, Büttner-Herold M, Lechler P, Kroening S, Goppelt-Struebe M, Schloetzer-Schrehardt U, Fuernrohr BG, Voll RE, Amann K, Eckardt KU, Christensen EI, Wiesener MS: (2013) Renal uptake of the antiapoptotic protein survivin is mediated by megalin at the apical membrane of the proximal tubule. Am J Physiol Renal Physiol. 2013;305(5): F734-44
Forster C, Schriewer J, John S, Eckardt KU, Willam C: (2013) Low-flow CO2 removal integrated into a renal-replacement circuit can reduce acidosis and decrease vasopressor requirements. Crit Care. 2013;17(4): R154
Eckardt KU, Coresh J, Devuyst O, Johnson RJ, Köttgen A, Levey AS, Levin A: (2013) Evolving importance of kidney disease: from subspecialty to global health burden. Lancet. 2013;382(9887): 158-69
Locatelli F, Bárány P, Covic A, De Francisco A, Del Vecchio L, Goldsmith D, Hörl W, London G, Vanholder R, Van Biesen W, ERA-EDTA ERBP Advisory Board , Abramovicz D, Cannata-Andia J, Cochat P, Eckardt KU, Fouque D, Heimburger O, Jäger K, Jenkins S, Lindley E, Macleod A, Marti-Monros A, Tattersall J, Wiecek A, Wanner C: (2013) Kidney Disease: Improving Global Outcomes guidelines on anaemia management in chronic kidney disease: a European Renal Best Practice position statement. Nephrol Dial Transplant. 2013;28(6): 1346-59
Boehlke C, Kotsis F, Buchholz B, Powelske C, Eckardt KU, Walz G, Nitschke R, Kuehn EW: (2013) Kif3a guides microtubular dynamics, migration and lumen formation of MDCK cells. PLoS ONE. 2013;8(5): e62165
Jacobi J, Prignitz A, Buttner M, Korn K, Weidemann A, Hilgers KF, Heller K, Velden J, Knöll A, Wullich B, May C, Eckardt KU, Amann KU: (2013) BK viremia and polyomavirus nephropathy in 352 kidney transplants; risk factors and potential role of mTOR inhibition. BMC Nephrol. 2013;14(): 207
Weidemann A, Breyer J, Rehm M, Eckardt KU, Daniel C, Cicha I, Giehl K, Goppelt-Struebe M: (2013) HIF-1? activation results in actin cytoskeleton reorganization and modulation of Rac-1 signaling in endothelial cells. Cell Commun Signal. 2013;11(): 80
Jörres A, John S, Lewington A, Ter Wee PM, Vanholder R, Van Biesen W, Tattersall J, ad-hoc working group of ERBP , Abramovic D, Cannata J, Cochat P, Eckardt KU, Heimburger O, Jäger K, Jenkins S, Lindley E, Locatelli F, London G, Macleod A, Spasovski G, Wanner C, Wiecek A, Zocalli C: (2013) A European Renal Best Practice (ERBP) position statement on the Kidney Disease Improving Global Outcomes (KDIGO) Clinical Practice Guidelines on Acute Kidney Injury: part 2: renal replacement therapy. Nephrol Dial Transplant. 2013;28(12): 2940-5
Prokosch HU, Mate S, Christoph J, Beck A, Köpcke F, Stephan S, Beckmann MW, Rau T, Hartmann A, Wullich B, Breil B, Eckardt KU, Titze S, Habermann JK, Ingenerf J, Hackmann M, Ries M, Bürkle T, Ganslandt T: (2012) Designing and implementing a biobanking IT framework for multiple research scenarios. Stud Health Technol Inform. 2012;180(): 559-63
Uhlig K, Eckardt KU: (2012) A Decade After the KDOQI CKD Guidelines: Impact on CKD Guidelines. Am J Kidney Dis. 2012;60(5): 705-6
Schley G, Klanke B, Schödel J, Kröning S, Türkoglu G, Beyer A, Hagos Y, Amann K, Burckhardt BC, Burzlaff N, Eckardt KU, Willam C: (2012) Selective stabilization of HIF-1? in renal tubular cells by 2-oxoglutarate analogues. Am J Pathol. 2012;181(5): 1595-606
Kopp C, Linz P, Hammon M, Schöfl C, Grauer M, Eckardt KU, Cavallaro A, Uder M, Luft FC, Titze J: (2012) Seeing the sodium in a patient with hypernatremia. Kidney Int. 2012;82(12): 1343-4
Eckardt KU, Kasiske BL: (2012) Foreword Kidney Int Suppl (2011). 2012;2(1): 7-7
Eckardt KU, Kasiske BL: (2012) KDIGO Clinical Practice Guideline for Glomerulonephritis Foreword Kidney Int Suppl (2011). 2012;2(2): 140-140
Wang Z, Schley G, Türkoglu G, Burzlaff N, Amann KU, Willam C, Eckardt KU, Bernhardt WM: (2012) The protective effect of prolyl-hydroxylase inhibition against renal ischaemia requires application prior to ischaemia but is superior to EPO treatment. Nephrol Dial Transplant. 2012;27(3): 929-36
Eckardt KU, Bärthlein B, Baid-Agrawal S, Beck A, Busch M, Eitner F, Ekici AB, Floege J, Gefeller O, Haller H, Hilge R, Hilgers KF, Kielstein JT, Krane V, Köttgen A, Kronenberg F, Oefner P, Prokosch HU, Reis A, Schmid M, Schaeffner E, Schultheiss UT, Seuchter SA, Sitter T, Sommerer C, Walz G, Wanner C, Wolf G, Zeier M, Titze S: (2012) The German Chronic Kidney Disease (GCKD) study: design and methods. Nephrol Dial Transplant. 2012;27(4): 1454-60
Kopp C, Linz P, Wachsmuth L, Dahlmann A, Horbach T, Schöfl C, Renz W, Santoro D, Niendorf T, Muller DN, Neininger M, Cavallaro A, Eckardt KU, Schmieder RE, Luft FC, Uder M, Titze J: (2012) (23)Na magnetic resonance imaging of tissue sodium. Hypertension. 2012;59(1): 167-72
Haag-Weber M, Eckardt KU, Hörl WH, Roger SD, Vetter A, Roth K: (2012) Safety, immunogenicity and efficacy of subcutaneous biosimilar epoetin-? (HX575) in non-dialysis patients with renal anemia: a multi-center, randomized, double-blind study. Clin Nephrol. 2012;77(1): 8-17
Kasiske BL, Eckardt KU: (2012) Evidence and Outcomes in CKD. Am J Kidney Dis. 2012;59(4): 492-4
Knier B, Bueschges-Seraphin B, Hilgers KF, Amann KU, Uder M, Eckardt KU, Jacobi J: (2012) From red to white urine: a patient's nightmare with a rather benign outcome. BMC Nephrol. 2012;13(): 7
Schietke RE, Hackenbeck T, Tran M, Günther R, Klanke B, Warnecke CL, Knaup KX, Shukla D, Rosenberger C, Koesters R, Bachmann S, Betz P, Schley G, Schödel J, Willam C, Winkler T, Amann K, Eckardt KU, Maxwell P, Wiesener MS: (2012) Renal Tubular HIF-2? Expression Requires VHL Inactivation and Causes Fibrosis and Cysts. PLoS ONE. 2012;7(1): e31034
Sever MS, Vanholder R, RDRTF of ISN Work Group on Recommendations for the Management of Crush Victims in Mass Disasters , Sever MS, Vanholder R, Ashkenazi I, Becker G, Better O, Covic A, De Smet M, Eckardt KU, Eknoyan G, Gibney N, Hoste E, Kazancioglu R, Lameire N, Luyckx V, Portilla D, Tuglular S, Van Biesen W: (2012) Recommendation for the management of crush victims in mass disasters. Nephrol Dial Transplant. 2012;27 Suppl 1(): i1-67
Hinkes B, Hilgers KF, Bolz HJ, Goppelt-Struebe M, Amann K, Nagl S, Bergmann C, Rascher W, Eckardt KU, Jacobi J: (2012) A complex microdeletion 17q12 phenotype in a patient with recurrent de novo membranous nephropathy. BMC Nephrol. 2012;13(): 27
Jantsch J, Schmidt B, Bardutzky J, Bogdan C, Eckardt KU, Raff U: (2011) Lethal varicella-zoster virus reactivation without skin lesions following renal transplantation. Nephrol Dial Transplant. 2011;26(1): 365-8
Hackenbeck T, Huber R, Schietke R, Knaup KX, Monti J, Wu X, Klanke B, Frey B, Gaipl U, Wullich B, Ferbus D, Goubin G, Warnecke C, Eckardt KU, Wiesener MS: (2011) The GTPase RAB20 is a HIF target with mitochondrial localization mediating apoptosis in hypoxia. BBA - MOL CELL RES. 2011;1813(1): 1-13
de Francisco AL, Kim J, Anker SD, Belozeroff V, Canaud B, Chazot C, Drueke TB, Eckardt KU, Floege J, Kronenberg F, Macdougall IC, Marcelli D, Molemans B, Passlick-Deetjen J, Schernthaner G, Stenvinkel P, Wheeler DC, Fouqueray B, Aljama P: (2011) An epidemiological study of hemodialysis patients based on the European Fresenius Medical Care hemodialysis network: results of the ARO study. Nephron Clin Pract. 2011;118(2): c143-54
Buchholz B, Teschemacher B, Schley G, Schillers H, Eckardt KU: (2011) Formation of cysts by principal-like MDCK cells depends on the synergy of cAMP- and ATP-mediated fluid secretion. J Mol Med. 2011;89(3): 251-61
Gronwald W, Klein MS, Zeltner R, Schulze BD, Reinhold SW, Deutschmann M, Immervoll AK, Böger CA, Banas B, Eckardt KU, Oefner PJ: (2011) Detection of autosomal dominant polycystic kidney disease by NMR spectroscopic fingerprinting of urine. Kidney Int. 2011;79(11): 1244-53
Buchholz B, Klanke B, Schley G, Bollag G, Tsai J, Kroening S, Yoshihara D, Wallace DP, Kraenzlin B, Gretz N, Hirth P, Eckardt KU, Bernhardt WM: (2011) The Raf kinase inhibitor PLX5568 slows cyst proliferation in rat polycystic kidney disease but promotes renal and hepatic fibrosis. Nephrol Dial Transplant. 2011;26(11): 3458-65
Floege J, Kim J, Ireland E, Chazot C, Drueke T, De Francisco A, Kronenberg F, Marcelli D, Passlick-Deetjen J, Schernthaner G, Fouqueray B, Wheeler DC, ARO Investigators , Floege J, Eckardt KU, Aljama P, Anker S, Canaud B, Chazot C, Drueke T, De Francisco A, Kronenberg F, Macdougall I, Schernthaner G, Stenvinkel P, Wheeler DC, Marcelli D, Passlick-Deetjen J, Fouqueray B, Ireland E, Kim J, Molemans B: (2011) Serum iPTH, calcium and phosphate, and the risk of mortality in a European haemodialysis population. Nephrol Dial Transplant. 2011;26(6): 1948-55
Herzog CA, Asinger RW, Berger AK, Charytan DM, Díez J, Hart RG, Eckardt KU, Kasiske BL, McCullough PA, Passman RS, Deloach SS, Pun PH, Ritz E: (2011) Cardiovascular disease in chronic kidney disease. A clinical update from Kidney Disease: Improving Global Outcomes (KDIGO). Kidney Int. 2011;80(6): 572-86
Jantsch J, Wiese M, Schödel J, Castiglione K, Gläsner J, Kolbe S, Mole D, Schleicher U, Eckardt KU, Hensel M, Lang R, Bogdan C, Schnare M, Willam C: (2011) Toll-like receptor activation and hypoxia use distinct signaling pathways to stabilize hypoxia-inducible factor 1? (HIF1A) and result in differential HIF1A-dependent gene expression. J Leukoc Biol. 2011;90(3): 551-62
Desai AS, Toto R, Jarolim P, Uno H, Eckardt KU, Kewalramani R, Levey AS, Lewis EF, McMurray JJ, Parving HH, Solomon SD, Pfeffer MA: (2011) Association Between Cardiac Biomarkers and the Development of ESRD in Patients With Type 2 Diabetes Mellitus, Anemia, and CKD. Am J Kidney Dis. 2011;58(5): 717-28
Levey AS, de Jong PE, Coresh J, El Nahas M, Astor BC, Matsushita K, Gansevoort RT, Kasiske BL, Eckardt KU: (2011) The definition, classification, and prognosis of chronic kidney disease: a KDIGO Controversies Conference report. Kidney Int. 2011;80(1): 17-28
Gansevoort RT, Matsushita K, van der Velde M, Astor BC, Woodward M, Levey AS, de Jong PE, Coresh J, Chronic Kidney Disease Prognosis Consortium , Levey A, El-Nahas M, de Jong PE, Coresh J, Eckardt KU, Kasiske BL, Woodward M, Ninomiya T, Chalmers J, MacMahon S, Tonelli M, Hemmelgarn B, Coresh J, Astor B, Matsushita K, Wang Y, Atkins RC, Polkinghorne KR, Chadban J, Dam B, Shankar A, Klein R, Klein BE, Tonelli M, Sacks F, Curhan G, Gansevoort RT, Shlipak M, Sarnak MJ, Katz R, Fried LP, Hallan S, Lydersen S, Holmen J, Lee BJ, Shlipak M, Sarnak MJ, Katz R, Fried LP, Ishani A, Neaton J, Svendsen K, Iseki K, Mann JF, Yusuf S, Teo KK, Gao P, Nelson RG, Knowler WC, Mann JF, Yusuf S, Teo K, Gao P, Astor BC, Auguste P, Coresh J, Gansevoort RT, de Jong PE, Matsushita K, van der Velde M, Veldhuis K, Wang Y, Woodward M, Camarata L, Thomas B, Manley T: (2011) Lower estimated GFR and higher albuminuria are associated with adverse kidney outcomes. A collaborative meta-analysis of general and high-risk population cohorts. Kidney Int. 2011;80(1): 93-104
van der Velde M, Matsushita K, Coresh J, Astor BC, Woodward M, Levey A, de Jong P, Gansevoort RT, Chronic Kidney Disease Prognosis Consortium , van der Velde M, Matsushita K, Coresh J, Astor BC, Woodward M, Levey AS, de Jong PE, Gansevoort RT, Levey A, El-Nahas M, Eckardt KU, Kasiske BL, Ninomiya T, Chalmers J, MacMahon S, Tonelli M, Hemmelgarn B, Sacks F, Curhan G, Collins AJ, Li S, Chen SC, Hawaii Cohort KP, Lee BJ, Ishani A, Neaton J, Svendsen K, Mann JF, Yusuf S, Teo KK, Gao P, Nelson RG, Knowler WC, Bilo HJ, Joosten H, Kleefstra N, Groenier KH, Auguste P, Veldhuis K, Wang Y, Camarata L, Thomas B, Manley T, van der Velde M, Matsushita K, Coresh J, Astor BC, Woodward M, Levey AS, de Jong PE, Gansevoort RT, Levey A, El-Nahas M, de Jong PE, Coresh J, Eckardt KU, Kasiske BL, Woodward M, Ninomiya T, Chalmers J, MacMahon S, Tonelli M, Hemmelgarn B, Tonelli M, Sacks F, Curhan G, Collins AJ, Li S, Chen SC, Lee BJ, Ishani A, Neaton J, Svendsen K, Mann JF, Yusuf S, Teo KK, Gao P, Nelson RG, Knowler WC, Mann JF, Yusuf S, Teo KK, Gao P, Bilo HJ, Joosten H, Kleefstra N, Groenier KH, Astor BC, Auguste P, Coresh J, Gansevoort RT, de Jong PE, Matsushita K, van der Velde M, Veldhuis K, Wang Y, Woodward M, Camarata L, Thomas B, Manley T: (2011) Lower estimated glomerular filtration rate and higher albuminuria are associated with all-cause and cardiovascular mortality. A collaborative meta-analysis of high-risk population cohorts. Kidney Int. 2011;79(12): 1341-52
Astor BC, Matsushita K, Gansevoort RT, van der Velde M, Woodward M, Levey AS, Jong PE, Coresh J, Chronic Kidney Disease Prognosis Consortium , Astor BC, Matsushita K, Gansevoort RT, van der Velde M, Woodward M, Levey AS, de Jong PE, Coresh J, El-Nahas M, Eckardt KU, Kasiske BL, Wright J, Appel L, Greene T, Levin A, Djurdjev O, Wheeler DC, Landray MJ, Townend JN, Emberson J, Clark LE, Macleod A, Marks A, Ali T, Fluck N, Prescott G, Smith DH, Weinstein JR, Johnson ES, Thorp ML, Wetzels JF, Blankestijn PJ, van Zuilen AD, Menon V, Sarnak M, Beck G, Kronenberg F, Kollerits B, Froissart M, Stengel B, Metzger M, Remuzzi G, Ruggenenti P, Perna A, Heerspink HJ, Brenner B, de Zeeuw D, Rossing P, Parving HH, Auguste P, Veldhuis K, Wang Y, Camarata L, Thomas B, Manley T, van der Velde M, Matsushita K, Coresh J, Astor BC, Woodward M, Levey AS, de Jong PE, Gansevoort RT, Levey A, El-Nahas M, de Jong PE, Coresh J, Eckardt KU, Kasiske BL, Woodward M, Ninomiya T, Chalmers J, MacMahon S, Tonelli M, Hemmelgarn B, Tonelli M, Sacks F, Curhan G, Collins AJ, Li S, Chen SC, Lee BJ, Ishani A, Neaton J, Svendsen K, Mann JF, Yusuf S, Teo KK, Gao P, Nelson RG, Knowler WC, Mann JF, Yusuf S, Teo KK, Gao P, Bilo HJ, Joosten H, Kleefstra N, Groenier KH, Astor BC, Auguste P, Coresh J, Gansevoort RT, de Jong PE, Matsushita K, van der Velde M, Veldhuis K, Wang Y, Woodward M, Camarata L, Thomas B, Manley T: (2011) Lower estimated glomerular filtration rate and higher albuminuria are associated with mortality and end-stage renal disease. A collaborative meta-analysis of kidney disease population cohorts. Kidney Int. 2011;79(12): 1331-40
Matzke GR, Aronoff GR, Atkinson AJ, Bennett WM, Decker BS, Eckardt KU, Golper T, Grabe DW, Kasiske B, Keller F, Kielstein JT, Mehta R, Mueller BA, Pasko DA, Schaefer F, Sica DA, Inker LA, Umans JG, Murray P: (2011) Drug dosing consideration in patients with acute and chronic kidney disease-a clinical update from Kidney Disease: Improving Global Outcomes (KDIGO). Kidney Int. 2011;80(11): 1122-37
Schley G, Klanke B, Schödel J, Forstreuter F, Shukla D, Kurtz A, Amann K, Wiesener MS, Rosen S, Eckardt KU, Maxwell PH, Willam C: (2011) Hypoxia-inducible transcription factors stabilization in the thick ascending limb protects against ischemic acute kidney injury. J Am Soc Nephrol. 2011;22(11): 2004-15
McMurray JJ, Uno H, Jarolim P, Desai AS, de Zeeuw D, Eckardt KU, Ivanovich P, Levey AS, Lewis EF, McGill JB, Parfrey P, Parving HH, Toto RM, Solomon SD, Pfeffer MA: (2011) Predictors of fatal and nonfatal cardiovascular events in patients with type 2 diabetes mellitus, chronic kidney disease, and anemia: an analysis of the Trial to Reduce cardiovascular Events with Aranesp (darbepoetin-alfa) Therapy (TREAT). Am Heart J. 2011;162(4): 748-755.e3
Levin NW, Kotanko P, Eckardt KU, Kasiske BL, Chazot C, Cheung AK, Redon J, Wheeler DC, Zoccali C, London GM: (2010) Blood pressure in chronic kidney disease stage 5D-report from a Kidney Disease: Improving Global Outcomes controversies conference. Kidney Int. 2010;77(4): 273-84
Luchner A, Weidemann A, Willenbrock R, Philipp S, Heinicke N, Rambausek M, Mehdorn U, Frankenberger B, Heid IM, Eckardt KU, Holmer SR: (2010) Improvement of the cardiac marker N-terminal-pro brain natriuretic peptide through adjustment for renal function: a stratified multicenter trial. Clin Chem Lab Med. 2010;48(1): 121-8
Jacobi J, Schnellhardt S, Kulschewski A, Amann KU, Kuefner MA, Eckardt KU, Hilgers KF: (2010) An unusual case of hyponatraemia. Nephrol Dial Transplant. 2010;25(3): 998-1001
Schietke RE, Warnecke C, Wacker I, Schödel J, Mole DR, Câmpean V, Amann K, Goppelt-Struebe M, Behrens J, Eckardt KU, Wiesener MS: (2010) The lysyl oxidases LOX and LOXL2 are necessary and sufficient to repress E-cadherin in hypoxia: insights into cellular transformation processes mediated by HIF-1. J Biol Chem. 2010;285(9): 6658-69
Machnik A, Dahlmann A, Kopp C, Goss J, Wagner H, van Rooijen N, Eckardt KU, Muller DN, Park JK, Luft FC, Kerjaschki D, Titze J: (2010) Mononuclear phagocyte system depletion blocks interstitial tonicity-responsive enhancer binding protein/vascular endothelial growth factor C expression and induces salt-sensitive hypertension in rats. Hypertension. 2010;55(3): 755-61
Hohenstein B, Kuo MC, Addabbo F, Yasuda K, Ratliff BB, Schwarzenberger C, Eckardt KU, Hugo CP, Goligorsky MS: (2010) Enhanced progenitor cell recruitment and endothelial repair after selective endothelial injury of the mouse kidney. Am J Physiol Renal Physiol. 2010;298(6): F1504-14
Jacobi J, Schnellhardt S, Opgenoorth M, Amann KU, Küttner A, Schmid A, Eckardt KU, Hilgers KF: (2010) Severe metabolic alkalosis and recurrent acute on chronic kidney injury in a patient with Crohn's disease. BMC Nephrol. 2010;11(): 6
Gimm T, Wiese M, Teschemacher B, Deggerich A, Schödel J, Knaup KX, Hackenbeck T, Hellerbrand C, Amann K, Wiesener MS, Höning S, Eckardt KU, Warnecke C: (2010) Hypoxia-inducible protein 2 is a novel lipid droplet protein and a specific target gene of hypoxia-inducible factor-1. FASEB J. 2010;24(11): 4443-58
Jürgensen JS, Grimm R, Benz K, Philipp S, Eckardt KU, Amann K: (2010) Effects of anemia and uremia and a combination of both on cardiovascular structures. Kidney Blood Press Res. 2010;33(4): 274-81
Walz G, Budde K, Mannaa M, Nürnberger J, Wanner C, Sommerer C, Kunzendorf U, Banas B, Hörl WH, Obermüller N, Arns W, Pavenstädt H, Gaedeke J, Büchert M, May C, Gschaidmeier H, Kramer S, Eckardt KU: (2010) Everolimus in patients with autosomal dominant polycystic kidney disease. N Engl J Med. 2010;363(9): 830-40
Schödel J, Bohr D, Klanke B, Schley G, Schlotzer-Schrehardt U, Warnecke C, Kurtz A, Amann K, Eckardt KU, Willam C: (2010) Factor inhibiting HIF limits the expression of hypoxia-inducible genes in podocytes and distal tubular cells. Kidney Int. 2010;78(9): 857-67
Eckardt KU, Kim J, Kronenberg F, Aljama P, Anker SD, Canaud B, Molemans B, Stenvinkel P, Schernthaner G, Ireland E, Fouqueray B, Macdougall IC: (2010) Hemoglobin variability does not predict mortality in European hemodialysis patients. J Am Soc Nephrol. 2010;21(10): 1765-75
Eckardt KU: (2010) Chronic kidney disease: Are elevated doses of ESAs associated with adverse outcomes? Nat Rev Nephrol. 2010;6(10): 566-8
Solomon SD, Uno H, Lewis EF, Eckardt KU, Lin J, Burdmann EA, de Zeeuw D, Ivanovich P, Levey AS, Parfrey P, Remuzzi G, Singh AK, Toto R, Huang F, Rossert J, McMurray JJ, Pfeffer MA, Trial to Reduce Cardiovascular Events with Aranesp Therapy (TREAT) Investigators: (2010) Erythropoietic response and outcomes in kidney disease and type 2 diabetes. N Engl J Med. 2010;363(12): 1146-55
Jacobi J, Hilgers KF, Lang W, Eckardt KU, Uder M: (2010) Images in vascular medicine: Renal arteriovenous fistula. Vasc Med. 2010;15(5): 433-4
Bernhardt WM, Wiesener MS, Scigalla P, Chou J, Schmieder RE, Günzler V, Eckardt KU: (2010) Inhibition of prolyl hydroxylases increases erythropoietin production in ESRD. J Am Soc Nephrol. 2010;21(12): 2151-6
Locatelli F, Eckardt KU, Macdougall IC, Tsakiris D, Clyne N, Burger HU, Scherhag A, Drueke TB, Cardiovascular Risk Reduction in Early Anaemia Trial with Epoetin Beta investigators and coordinators: (2010) Value of N-terminal brain natriuretic peptide as a prognostic marker in patients with CKD: results from the CREATE study. Curr Med Res Opin. 2010;26(11): 2543-52
Romaker D, Puetz M, Teschner S, Donauer J, Geyer M, Gerke P, Rumberger B, Dworniczak B, Pennekamp P, Buchholz B, Neumann HP, Kumar R, Gloy J, Eckardt KU, Walz G: (2009) Increased expression of secreted frizzled-related protein 4 in polycystic kidneys. J Am Soc Nephrol. 2009;20(1): 48-56
Eckardt KU: (2009) Erythropoietin and microvascular diabetic complications. Nephrol Dial Transplant. 2009;24(2): 388-90
Knaup KX, Jozefowski K, Schmidt R, Bernhardt WM, Weidemann A, Juergensen JS, Warnecke C, Eckardt KU, Wiesener MS: (2009) Mutual regulation of hypoxia-inducible factor and mammalian target of rapamycin as a function of oxygen availability. Mol Cancer Res. 2009;7(1): 88-98
Locatelli F, Covic A, Eckardt KU, Wiecek A, Vanholder R, ERA-EDTA ERBP Advisory Board: (2009) Anaemia management in patients with chronic kidney disease: a position statement by the Anaemia Working Group of European Renal Best Practice (ERBP). Nephrol Dial Transplant. 2009;24(2): 348-54
Hackenbeck T, Knaup KX, Schietke R, Schödel J, Willam C, Wu X, Warnecke C, Eckardt KU, Wiesener MS: (2009) HIF-1 or HIF-2 induction is sufficient to achieve cell cycle arrest in NIH3T3 mouse fibroblasts independent from hypoxia. Cell Cycle. 2009;8(9): 1386-95
Schödel J, Klanke B, Weidemann A, Buchholz B, Bernhardt W, Bertog M, Amann K, Korbmacher C, Wiesener M, Warnecke C, Kurtz A, Eckardt KU, Willam C: (2009) HIF-prolyl hydroxylases in the rat kidney: physiologic expression patterns and regulation in acute kidney injury. Am J Pathol. 2009;174(5): 1663-74
Machnik A, Neuhofer W, Jantsch J, Dahlmann A, Tammela T, Machura K, Park JK, Beck FX, Muller DN, Derer W, Goss J, Ziomber A, Dietsch P, Wagner H, van Rooijen N, Kurtz A, Hilgers KF, Alitalo K, Eckardt KU, Luft FC, Kerjaschki D, Titze J: (2009) Macrophages regulate salt-dependent volume and blood pressure by a vascular endothelial growth factor-C-dependent buffering mechanism. Nat Med. 2009;15(5): 545-52
Eckardt KU, Berns JS, Rocco MV, Kasiske BL: (2009) Definition and classification of CKD: the debate should be about patient prognosis--a position statement from KDOQI and KDIGO. Am J Kidney Dis. 2009;53(6): 915-20
Wiesener MS, Maxwell PH, Eckardt KU: (2009) Novel insights into the role of the tumor suppressor von Hippel Lindau in cellular differentiation, ciliary biology, and cyst repression. J Mol Med. 2009;87(9): 871-7
Eckardt KU, Kasiske BL: (2009) Foreword. Kidney Int. 2009;76(S113): S1-S2
Eckardt KU: (2009) Frontiers in the pathogenesis of kidney disease. J Mol Med. 2009;87(9): 837-9
Kasiske B, Eckardt KU: (2009) Primum non Nocere. Am J Transplant. 2009;9(9): 2204
Machura K, Steppan D, Neubauer B, Alenina N, Coffman TM, Facemire CM, Hilgers KF, Eckardt KU, Wagner C, Kurtz A: (2009) Developmental renin expression in mice with a defective renin-angiotensin system. Am J Physiol Renal Physiol. 2009;297(5): F1371-80
Tanaka T, Wiesener MS, Bernhardt W, Eckardt KU, Warnecke C: (2009) The human HIF (hypoxia-inducible factor)-3alpha gene is a HIF-1 target gene and may modulate hypoxic gene induction. Biochem J. 2009;424(1): 143-51
Eckardt KU, Kasiske BL: (2009) Kidney disease: improving global outcomes. Nat Rev Nephrol. 2009;5(11): 650-7
Moe SM, Drueke TB, Block GA, Cannata-Andia JB, Elder GJ, Fukagawa M, Jorgetti V, Ketteler M, Langman CB, Levin A, MacLeod AM, McCann L, McCullough PA, Ott SM, Wang AYM, Weisinger JR, Wheeler DC, Eckardt KU, Kasiske BL, Uhlig K, Moorthi R, Earley A, Persson R: (2009) Introduction and definition of CKD-MBD and the development of the guideline statements Kidney Int. 2009;76 Suppl. (): S3-S130
Pfeffer MA, Burdmann EA, Chen CY, Cooper ME, de Zeeuw D, Eckardt KU, Ivanovich P, Kewalramani R, Levey AS, Lewis EF, McGill J, McMurray JJ, Parfrey P, Parving HH, Remuzzi G, Singh AK, Solomon SD, Toto R, Uno H, TREAT Investigators: (2009) Baseline characteristics in the Trial to Reduce Cardiovascular Events With Aranesp Therapy (TREAT). Am J Kidney Dis. 2009;54(1): 59-69
Macdougall IC, Rossert J, Casadevall N, Stead RB, Duliege AM, Froissart M, Eckardt KU: (2009) A peptide-based erythropoietin-receptor agonist for pure red-cell aplasia. N Engl J Med. 2009;361(19): 1848-55
Eckardt KU, Scherhag A, Macdougall IC, Tsakiris D, Clyne N, Locatelli F, Zaug MF, Burger HU, Drueke TB: (2009) Left ventricular geometry predicts cardiovascular outcomes associated with anemia correction in CKD. J Am Soc Nephrol. 2009;20(12): 2651-60
Bernhardt WM, Gottmann U, Doyon F, Buchholz B, Câmpean V, Schödel J, Reisenbuechler A, Klaus S, Arend M, Flippin L, Willam C, Wiesener MS, Yard B, Warnecke C, Eckardt KU: (2009) Donor treatment with a PHD-inhibitor activating HIFs prevents graft injury and prolongs survival in an allogenic kidney transplant model. Proc Natl Acad Sci U S A. 2009;106(50): 21276-81
Volke M, Gale DP, Maegdefrau U, Schley G, Klanke B, Bosserhoff AK, Maxwell PH, Eckardt KU, Warnecke C: (2009) Evidence for a lack of a direct transcriptional suppression of the iron regulatory peptide hepcidin by hypoxia-inducible factors. PLoS ONE. 2009;4(11): e7875
Ritz E, Krum H, Schlaich M, Whitbourn R, Sobotka PA, Sadowski J, Bartus K, Kapelak B, Walton A, Sievert H, Thambar S, Abraham WT, Esler M, Wang Y, Tsun Z, Machnik A, Neuhofer W, Jantsch J, Dahlmann A, Tammela T, Machura K, Park JK, Beck FX, Muller DN, Derer W, Goss J, Ziomber A, Dietsch P, Wagner H, van Rooijen N, Kurtz A, Hilgers KF, Alitalo K, Eckardt KU, Luft FC, Kerjaschki D, Titze J: (2009) New approaches to pathogenesis and management of hypertension. Clin J Am Soc Nephrol. 2009;4(12): 1886-91
Pfeffer MA, Burdmann EA, Chen CY, Cooper ME, de Zeeuw D, Eckardt KU, Feyzi JM, Ivanovich P, Kewalramani R, Levey AS, Lewis EF, McGill JB, McMurray JJ, Parfrey P, Parving HH, Remuzzi G, Singh AK, Solomon SD, Toto R, TREAT Investigators: (2009) A trial of darbepoetin alfa in type 2 diabetes and chronic kidney disease. N Engl J Med. 2009;361(21): 2019-32
Möckel M, Radovic M, Kühnle Y, Combé V, Waigand J, Schröder S, Dietz R, Frei U, Eckardt KU: (2008) Acute renal haemodynamic effects of radiocontrast media in patients undergoing left ventricular and coronary angiography. Nephrol Dial Transplant. 2008;23(5): 1588-94
Weidemann A, Bernhardt WM, Klanke B, Daniel C, Buchholz B, Câmpean V, Amann K, Warnecke C, Wiesener MS, Eckardt KU, Willam C: (2008) HIF activation protects from acute kidney injury. J Am Soc Nephrol. 2008;19(3): 486-94
Jantsch J, Chakravortty D, Turza N, Prechtel AT, Buchholz B, Gerlach RG, Volke M, Gläsner J, Warnecke C, Wiesener MS, Eckardt KU, Steinkasserer A, Hensel M, Willam C: (2008) Hypoxia and Hypoxia-Inducible Factor-1{alpha} Modulate Lipopolysaccharide-Induced Dendritic Cell Activation and Function. J Immunol. 2008;180(7): 4697-705
Warnecke C, Weidemann A, Volke M, Schietke R, Wu X, Knaup KX, Hackenbeck T, Bernhardt W, Willam C, Eckardt KU, Wiesener MS: (2008) The specific contribution of hypoxia-inducible factor-2alpha to hypoxic gene expression in vitro is limited and modulated by cell type-specific and exogenous factors. Exp Cell Res. 2008;314(10): 2016-27
Boutin AT, Weidemann A, Fu Z, Mesropian L, Gradin K, Jamora C, Wiesener M, Eckardt KU, Koch CJ, Ellies LG, Haddad G, Haase VH, Simon MC, Poellinger L, Powell FL, Johnson RS: (2008) Epidermal sensing of oxygen is essential for systemic hypoxic response. Cell. 2008;133(2): 223-34
Rosenberger C, Rosen S, Shina A, Frei U, Eckardt KU, Flippin LA, Arend M, Klaus SJ, Heyman SN: (2008) Activation of hypoxia-inducible factors ameliorates hypoxic distal tubular injury in the isolated perfused rat kidney. Nephrol Dial Transplant. 2008;23(11): 3472-8
Jantsch J, Turza N, Volke M, Eckardt KU, Hensel M, Steinkasserer A, Willam C, Prechtel AT: (2008) Small interfering RNA (siRNA) delivery into murine bone marrow-derived dendritic cells by electroporation. J Immunol Methods. 2008;337(1): 71-77
Hugo C, Schott G, Eckardt KU, Wullich B: (2008) [ABO-incompatible renal transplantation - why and how?] Urologe A. 2008;47(9): 1074-8
Hagel S, Jantsch J, Budde U, Kalden JR, Eckardt KU, Veelken R: (2008) Treatment of acquired thrombotic thrombocytopenic purpura (TTP) with plasma infusion plus rituximab. Thromb Haemost. 2008;100(1): 151-3
Locatelli F, Nissenson AR, Barrett BJ, Walker RG, Wheeler DC, Eckardt KU, Lameire NH, Eknoyan G: (2008) Clinical practice guidelines for anemia in chronic kidney disease: problems and solutions. A position statement from Kidney Disease: Improving Global Outcomes (KDIGO). Kidney Int. 2008;74(10): 1237-40
Murray PT, Devarajan P, Levey AS, Eckardt KU, Bonventre JV, Lombardi R, Herget-Rosenthal S, Levin A: (2008) A framework and key research questions in AKI diagnosis and staging in different environments Clin J Am Soc Nephrol. 2008;3(3): 864-868
Ziomber A, Machnik A, Dahlmann A, Dietsch P, Beck FX, Wagner H, Hilgers KF, Luft FC, Eckardt KU, Titze J: (2008) Sodium-, potassium-, chloride-, and bicarbonate-related effects on blood pressure and electrolyte homeostasis in deoxycorticosterone acetate-treated rats. Am J Physiol Renal Physiol. 2008;295(6): F1752-63
Bernhardt WM, Eckardt KU: (2008) Physiological basis for the use of erythropoietin in critically ill patients at risk for acute kidney injury. Curr Opin Crit Care. 2008;14(6): 621-6
Zoccali C, Abramowicz D, Cannata-Andia JB, Cochat P, Covic A, Eckardt KU, Fouque D, Heimburger O, McLeod A, Lindley E, Locatelli F, Spasovski G, Tattersall J, Van Biesen W, Wanner C, Vanholder R, European Best Practice Guidelines , European Renal Best Practice: (2008) European best practice quo vadis? From European Best Practice Guidelines (EBPG) to European Renal Best Practice (ERBP). Nephrol Dial Transplant. 2008;23(7): 2162-6
Weidemann A, Klanke B, Wagner M, Volk T, Willam C, Wiesener MS, Eckardt KU, Warnecke C: (2008) Hypoxia, via stabilization of the hypoxia-inducible factor HIF-1alpha, is a direct and sufficient stimulus for brain-type natriuretic peptide induction. Biochem J. 2008;409(1): 233-42
Rosenberger C, Khamaisi M, Abassi Z, Shilo V, Weksler-Zangen S, Goldfarb M, Shina A, Zibertrest F, Eckardt KU, Rosen S, Heyman SN: (2008) Adaptation to hypoxia in the diabetic rat kidney. Kidney Int. 2008;73(1): 34-42
Rosenberger C, Goldfarb M, Shina A, Bachmann S, Frei U, Eckardt KU, Schrader T, Rosen S, Heyman SN: (2008) Evidence for sustained renal hypoxia and transient hypoxia adaptation in experimental rhabdomyolysis-induced acute kidney injury. Nephrol Dial Transplant. 2008;23(4): 1135-43
Oppert M, Engel C, Brunkhorst FM, Bogatsch H, Reinhart K, Frei U, Eckardt KU, Loeffler M, John S, German Competence Network Sepsis (SepNet): (2008) Acute renal failure in patients with severe sepsis and septic shock--a significant independent risk factor for mortality: results from the German Prevalence Study. Nephrol Dial Transplant. 2008;23(3): 904-9
Rosenberger C, Pratschke J, Rudolph B, Heyman SN, Schindler R, Babel N, Eckardt KU, Frei U, Rosen S, Reinke P: (2007) Immunohistochemical detection of hypoxia-inducible factor-1alpha in human renal allograft biopsies. J Am Soc Nephrol. 2007;18(1): 343-51
Schafflhuber M, Volpi N, Dahlmann A, Hilgers KF, Maccari F, Dietsch P, Wagner H, Luft FC, Eckardt KU, Titze J: (2007) Mobilization of osmotically inactive Na+ by growth and by dietary salt restriction in rats. Am J Physiol Renal Physiol. 2007;292(5): F1490-500
Bernhardt WM, Wiesener MS, Weidemann A, Schmitt R, Weichert W, Lechler P, Câmpean V, Ong AC, Willam C, Gretz N, Eckardt KU: (2007) Involvement of hypoxia-inducible transcription factors in polycystic kidney disease. Am J Pathol. 2007;170(3): 830-42
Rosenberger C, Solovan C, Rosenberger AD, Jinping L, Treudler R, Frei U, Eckardt KU, Brown LF: (2007) Upregulation of hypoxia-inducible factors in normal and psoriatic skin. J Invest Dermatol. 2007;127(10): 2445-52
Eckardt KU, Bernhardt W, Willam C, Wiesener M: (2007) Hypoxia-inducible transcription factors and their role in renal disease. Semin Nephrol. 2007;27(3): 363-72
Hohenstein B, Uder M, Willam C, Amann KU, Eckardt KU, Hugo CP: (2007) Transvenous renal biopsy of a kidney transplant in a patient with a suspected bleeding disorder. Am J Transplant. 2007;7(8): 2052-3
Levey AS, Atkins R, Coresh J, Cohen EP, Collins AJ, Eckardt KU, Nahas ME, Jaber BL, Jadoul M, Levin A, Powe NR, Rossert J, Wheeler DC, Lameire N, Eknoyan G: (2007) Chronic kidney disease as a global public health problem: approaches and initiatives - a position statement from Kidney Disease Improving Global Outcomes. Kidney Int. 2007;72(3): 247-59
Drueke TB, Eckardt KU, Scherhag A: (2007) Chronic kidney disease, anemia, and epoetin - Reply N Engl J Med. 2007;356(9): 959-959
Van Wyck D, Eckardt KU, Uhlig K, Rocco M, Levin A: (2007) Response to Clin J Am Soc Nephrol. 2007;2(1): 13-14
Wiesener MS, Münchenhagen P, Glaser M, Sobottka BA, Knaup KX, Jozefowski K, Jürgensen JS, Roigas J, Warnecke C, Gröne HJ, Maxwell PH, Willam C, Eckardt KU: (2007) Erythropoietin gene expression in renal carcinoma is considerably more frequent than paraneoplastic polycythemia. Int J Cancer. 2007;121(11): 2434-42
Van Wyck D, Eckardt KU, Uhlig K, Rocco M, Levin A: (2007) Appraisal of evidence and control of bias in the kidney disease outcomes quality initiative guideline development process. Clin J Am Soc Nephrol. 2007;2(1): 8-10
Van Wyck D, Eckardt KU, Uhlig K, Rocco M, Levin A: (2007) Response to "influence of industry on renal guideline development". Clin J Am Soc Nephrol. 2007;2(1): 13-4
Eckardt KU: (2007) [What are the aims and targets of renal anemia therapy?] Dtsch Med Wochenschr. 2007;132(36): 1837-41
Macdougall IC, Eckardt KU, Locatelli F: (2007) Latest US KDOQI Anaemia Guidelines update what are the implications for Europe? Nephrol Dial Transplant. 2007;22(10): 2738-42
John S, Eckardt KU: (2007) Renal replacement strategies in the ICU. Chest. 2007;132(4): 1379-88
Lechler P, Wu X, Bernhardt W, Câmpean V, Gastiger S, Hackenbeck T, Klanke B, Weidemann A, Warnecke C, Amann K, Engehausen D, Willam C, Eckardt KU, Rödel F, Wiesener MS: (2007) The tumor gene survivin is highly expressed in adult renal tubular cells: implications for a pathophysiological role in the kidney. Am J Pathol. 2007;171(5): 1483-98
Bernhardt WM, Warnecke C, Willam C, Tanaka T, Wiesener MS, Eckardt KU: (2007) Organ protection by hypoxia and hypoxia-inducible factors. Methods Enzymol. 2007;435(): 219-45
Higgins DF, Kimura K, Bernhardt WM, Shrimanker N, Akai Y, Hohenstein B, Saito Y, Johnson RS, Kretzler M, Cohen CD, Eckardt KU, Iwano M, Haase VH: (2007) Hypoxia promotes fibrogenesis in vivo via HIF-1 stimulation of epithelial-to-mesenchymal transition. J Clin Invest. 2007;117(12): 3810-3820
Nangaku M, Eckardt KU: (2007) Hypoxia and the HIF system in kidney disease. J Mol Med. 2007;85(12): 1325-30
Willam C, Warnecke C, Schefold JC, Kügler J, Koehne P, Frei U, Wiesener M, Eckardt KU: (2006) Inconsistent effects of acidosis on HIF-alpha protein and its target genes. Pflugers Arch. 2006;451(4): 534-43
Lauschke A, Teichgräber UK, Frei U, Eckardt KU: (2006) 'Low-dose' dopamine worsens renal perfusion in patients with acute renal failure. Kidney Int. 2006;69(9): 1669-74
Jacobi J, Porst M, Cordasic N, Namer B, Schmieder RE, Eckardt KU, Hilgers KF: (2006) Subtotal nephrectomy impairs ischemia-induced angiogenesis and hindlimb re-perfusion in rats. Kidney Int. 2006;69(11): 2013-21
Rosenberger C, Rosen S, Shina A, Bernhardt W, Wiesener MS, Frei U, Eckardt KU, Heyman SN: (2006) Hypoxia-inducible factors and tubular cell survival in isolated perfused kidneys. Kidney Int. 2006;70(1): 60-70
Titze J, Luft FC, Bauer K, Dietsch P, Lang R, Veelken R, Wagner H, Eckardt KU, Hilgers KF: (2006) Extrarenal Na+ balance, volume, and blood pressure homeostasis in intact and ovariectomized deoxycorticosterone-acetate salt rats. Hypertension. 2006;47(6): 1101-7
Bernhardt WM, Câmpean V, Kany S, Jürgensen JS, Weidemann A, Warnecke C, Arend M, Klaus S, Günzler V, Amann K, Willam C, Wiesener MS, Eckardt KU: (2006) Preconditional activation of hypoxia-inducible factors ameliorates ischemic acute renal failure. J Am Soc Nephrol. 2006;17(7): 1970-8
Willam C, Maxwell PH, Nichols L, Lygate C, Tian YM, Bernhardt W, Wiesener M, Ratcliffe PJ, Eckardt KU, Pugh CW: (2006) HIF prolyl hydroxylases in the rat; organ distribution and changes in expression following hypoxia and coronary artery ligation. J Mol Cell Cardiol. 2006;41(1): 68-77
Macdougall IC, Eckardt KU: (2006) Novel strategies for stimulating erythropoiesis and potential new treatments for anaemia. Lancet. 2006;368(9539): 947-53
Nangaku M, Eckardt KU: (2006) Pathogenesis of renal anemia. Semin Nephrol. 2006;26(4): 261-8
Drueke TB, Locatelli F, Clyne N, Eckardt KU, Macdougall IC, Tsakiris D, Burger HU, Scherhag A, CREATE Investigators: (2006) Normalization of hemoglobin level in patients with chronic kidney disease and anemia. N Engl J Med. 2006;355(20): 2071-84
John S, Eckardt KU: (2006) Renal replacement therapy in the treatment of acute renal failure-intermittent and continuous. Semin Dial. 2006;19(6): 455-64
Bernhardt WM, Schmitt R, Rosenberger C, Münchenhagen PM, Gröne HJ, Frei U, Warnecke C, Bachmann S, Wiesener MS, Willam C, Eckardt KU: (2006) Expression of hypoxia-inducible transcription factors in developing human and rat kidneys. Kidney Int. 2006;69(1): 114-22
Goldfarb M, Rosenberger C, Abassi Z, Shina A, Zilbersat F, Eckardt KU, Rosen S, Heyman SN: (2006) Acute-on-Chronic Renal Failure in the Rat: Functional Compensation and Hypoxia Tolerance. Am J Nephrol. 2006;26(1): 22-33
Philipp S, Jürgensen JS, Fielitz J, Bernhardt WM, Weidemann A, Schiche A, Pilz B, Dietz R, Regitz-Zagrosek V, Eckardt KU, Willenbrock R: (2006) Stabilization of hypoxia inducible factor rather than modulation of collagen metabolism improves cardiac function after acute myocardial infarction in rats. Eur J Heart Fail. 2006;8(4): 347-54
Voegeli TA, Kurtz A, Grimm MO, Effert P, Eckardt KU: (2005) Anemia under androgen deprivation: influence of flutamide, cyproteroneacetate and orchiectomy on the erythropoietin system. Horm Metab Res. 2005;37(2): 89-93
Boven K, Knight J, Bader F, Rossert J, Eckardt KU, Casadevall N: (2005) Epoetin-associated pure red cell aplasia in patients with chronic kidney disease: solving the mystery. Nephrol Dial Transplant. 2005;20 Suppl 3(): iii33-iii40
Rossert J, Eckardt KU: (2005) Erythropoietin receptors: their role beyond erythropoiesis. Nephrol Dial Transplant. 2005;20(6): 1025-8
Lameire N, Eknoyan G, Barsoum R, Eckardt KU, Levin A, Levin N, Locatelli F, Macleod A, Vanholder R, Walker R, Wang H: (2005) A new initiative in nephrology: kidney disease: improving global outcomes. Contrib Nephrol. 2005;149(): 90-9
Levey AS, Eckardt KU, Tsukamoto Y, Levin A, Coresh J, Rossert J, Zeeuw D, Hostetter TH, Lameire N, Eknoyan G: (2005) Definition and classification of chronic kidney disease: A position statement from Kidney Disease: Improving Global Outcomes (KDIGO). Kidney Int. 2005;67(6): 2089-100
Titze J, Bauer K, Schafflhuber M, Dietsch P, Lang R, Schwind KH, Luft FC, Eckardt KU, Hilgers KF: (2005) Internal Sodium Balance in Desoxycorticosterone Acetate-Salt Rats: A Body Composition Study. Am J Physiol Renal Physiol. 2005;289(4): F793-802
Casadevall N, Eckardt KU, Rossert J: (2005) Epoetin-induced autoimmune pure red cell aplasia. J Am Soc Nephrol. 2005;16 Suppl 1(): S67-9
Eckardt KU: (2005) Managing a fateful alliance: anaemia and cardiovascular outcomes. Nephrol Dial Transplant. 2005;20 Suppl 6(): vi16-vi20
Corwin HL, Eckardt KU: (2005) Erythropoietin in the critically ill: what is the evidence? Nephrol Dial Transplant. 2005;20(12): 2605-8
Eckardt KU, Bernhardt WM, Weidemann A, Warnecke C, Rosenberger C, Wiesener MS, Willam C: (2005) Role of hypoxia in the pathogenesis of renal disease Kidney Int. 2005;68 Suppl. (): 46-51
Kruger A, Eckardt KU: (2005) Pure red cell aplasia induced by antibodies against human recombinant erythropoietin Transfus Med Hemother. 2005;32(2): 97-100
Oppert M, Schindler R, Husung C, Offermann K, Gräf KJ, Boenisch O, Barckow D, Frei U, Eckardt KU: (2005) Low-dose hydrocortisone improves shock reversal and reduces cytokine levels in early hyperdynamic septic shock. Crit Care Med. 2005;33(11): 2457-64
Eckardt KU, Kurtz A: (2005) Regulation of erythropoietin production. Eur J Clin Invest. 2005;35 Suppl 3(): 13-9
Eckardt KU, Bernhardt WM, Weidemann A, Warnecke C, Rosenberger C, Wiesener MS, Willam C: (2005) Role of hypoxia in the pathogenesis of renal disease. Kidney Int Suppl. 2005;(99): S46-51
Titze J, Bauer K, Schafflhuber M, Dietsch P, Lang R, Schwind KH, Luft FC, Eckardt KU, Hilgers KF: (2005) Internal sodium balance in DOCA-salt rats: a body composition study.(vol 289, 793, 2005) Am J Physiol Renal Physiol. 2005;290(2): F561-F562
Titze J, Luft FC, Bauer K, Dietsch P, Veelken R, Schwind KH, Eckardt KU, Hilgers KF: (2005) Doca-salt is a largely volume-independent hypertension and is influenced by ovarian function Hypertension. 2005;46(5): 850-850
Knaup K, Weidemann A, Jozefowski K, Jürgensen JS, Eckardt KU, Wiesener M: (2005) Inhibition of mTOR attenuates hypoxic gene regulation in renal cells Nephrol Dial Transplant. 2005;20 Suppl.(): V16-V17
Titze J, Schafflhuber M, Dietsch P, Volpi N, Luft FC, Eckardt KU, Hilgers KF: (2005) Osmotically inactive skin Na+ storage involves a glycosaminoglycan cation exchange mechanism Nephrol Dial Transplant. 2005;20 Suppl.(): V22-V23
Titze J, Bauer K, Dietsch P, Schwind KH, Lang R, Luft FC, Eckardt KU, Hilgers KF: (2005) Internal DOCA escape in rats Nephrol Dial Transplant. 2005;20 Suppl.(): V42-V43
Bernhardt WM, Kany S, Câmpean V, Jürgensen JS, Weidemann A, Warnecke C, Willam C, Frei U, Amann K, Wiesener MS, Eckardt KU: (2005) Preconditional induction of HIF by carbon monoxide ameliorates ischemic acute renal failure Nephrol Dial Transplant. 2005;20 Suppl.(): V54-V54
Rosenberger C, Heyman SN, Rosen S, Shina A, Goldfarb M, Griethe W, Frei U, Reinke P, Bachmann S, Eckardt KU: (2005) Up-regulation of HIF in experimental acute renal failure: evidence for a protective transcriptional response to hypoxia. Kidney Int. 2005;67(2): 531-42
Rossert J, Maroni B, Aljama P, Casadevall N, Cooper M, Delage R, Eckardt KU, de Francisco AML, Hörl W, Jelkmann W, Johnson D, Locatelli F, Macdougall I, Nissenson AR, Pollock C, Schellekens H, Thorpe R, Toffelmire E: (2005) Erythropoietin-induced, antibody-mediated pure red cell aplasia Eur J Clin Invest. 2005;35 Suppl.(): 95-99
Locatelli F, Aljama P, Bárány P, Canaud B, Carrera F, Eckardt KU, Macdougall IC, Macleod A, Hörl WH, Wiecek A, Cameron S: (2004) Erythropoiesis-stimulating agents and antibody-mediated pure red-cell aplasia: here are we now and where do we go from here? Nephrol Dial Transplant. 2004;19(2): 288-93
Locatelli F, Aljama P, Bárány P, Canaud B, Carrera F, Eckardt KU, Hörl WH, Macdougal IC, Macleod A, Wiecek A, Cameron S: (2004) Revised European best practice guidelines for the management of anaemia in patients with chronic renal failure. Nephrol Dial Transplant. 2004;19 Suppl 2(): ii1-47
Rossert J, Casadevall N, Eckardt KU: (2004) Anti-erythropoietin antibodies and pure red cell aplasia. J Am Soc Nephrol. 2004;15(2): 398-406
Wellmann S, Guschmann M, Griethe W, Eckert C, von Stackelberg A, Lottaz C, Moderegger E, Einsiedel HG, Eckardt KU, Henze G, Seeger K, Stackelberg A: (2004) Activation of the HIF pathway in childhood ALL, prognostic implications of VEGF. Leukemia. 2004;18(5): 926-33
Oppert M, Jörres A, Barckow D, Eckardt KU, Frei U, Kaisers U: (2004) Inhaled nitric oxide for ARDS due to sickle cell disease. Swiss Med Wkly. 2004;134(11-12): 165-7
Verhelst D, Rossert J, Casadevall N, Kruger A, Eckardt KU, Macdougall IC: (2004) Treatment of erythropoietin-induced pure red cell aplasia: a retrospective study. Lancet. 2004;363(9423): 1768-71
Warnecke C, Zaborowska Z, Kurreck J, Erdmann VA, Frei U, Wiesener M, Eckardt KU: (2004) Differentiating the functional role of hypoxia-inducible factor (HIF)-1alpha and HIF-2alpha (EPAS-1) by the use of RNA interference: erythropoietin is a HIF-2alpha target gene in Hep3B and Kelly cells. FASEB J. 2004;18(12): 1462-4
Jürgensen JS, Rosenberger C, Wiesener MS, Warnecke C, Hörstrup JH, Gräfe M, Philipp S, Griethe W, Maxwell PH, Frei U, Bachmann S, Willenbrock R, Eckardt KU: (2004) Persistent induction of HIF-1alpha and -2alpha in cardiomyocytes and stromal cells of ischemic myocardium. FASEB J. 2004;18(12): 1415-7
Ebbesen P, Eckardt KU, Ciampor F, Pettersen EO: (2004) Linking measured intercellular oxygen concentration to human cell functions. Acta Oncol. 2004;43(6): 598-600
Eknoyan G, Lameire N, Barsoum R, Eckardt KU, Levin A, Levin N, Locatelli F, Macleod A, Vanholder R, Walker R, Wang H: (2004) The burden of kidney disease: improving global outcomes. Kidney Int. 2004;66(4): 1310-4
Wiesener MS, Jürgensen JS, Rosenberger C, Scholze CK, Hörstrup JH, Warnecke C, Mandriota S, Bechmann I, Frei UA, Pugh CW, Ratcliffe PJ, Bachmann S, Maxwell PH, Eckardt KU: (2003) Widespread hypoxia-inducible expression of HIF-2alpha in distinct cell populations of different organs. FASEB J. 2003;17(2): 271-3
Warnecke C, Griethe W, Weidemann A, Jürgensen JS, Willam C, Bachmann S, Ivashchenko Y, Wagner I, Frei U, Wiesener M, Eckardt KU: (2003) Activation of the hypoxia-inducible factor-pathway and stimulation of angiogenesis by application of prolyl hydroxylase inhibitors. FASEB J. 2003;17(9): 1186-8
Jürgensen JS, Kettritz R, Schneider W, Koop H, Hildebrand TS, Frei U, Eckardt KU: (2003) Catastrophic antiphospholipid syndrome masquerading as ischaemic colitis. Rheumatol Int. 2003;23(4): 204-6
Eckardt KU, Casadevall N: (2003) Pure red-cell aplasia due to anti-erythropoietin antibodies. Nephrol Dial Transplant. 2003;18(5): 865-9
Locatelli F, Canaud B, Eckardt KU, Stenvinkel P, Wanner C, Zoccali C: (2003) Oxidative stress in end-stage renal disease: an emerging threat to patient outcome. Nephrol Dial Transplant. 2003;18(7): 1272-80
Locatelli F, Canaud B, Eckardt KU, Stenvinkel P, Wanner C, Zoccali C: (2003) The importance of diabetic nephropathy in current nephrological practice. Nephrol Dial Transplant. 2003;18(9): 1716-25
Ritz E, Eckardt KU, Grabensee B, Hörl W, Philipp T: (2003) [Reflections on the World Congress for Nephrology] Dtsch Med Wochenschr. 2003;128(22): 1215
Eckardt KU, Rosenberger C, Jürgensen JS, Wiesener MS: (2003) Role of hypoxia in the pathogenesis of renal disease. Blood Purif. 2003;21(3): 253-7
Baginski S, Körner R, Frei U, Eckardt KU: (2003) [Anemia and erythropoietin in critically ill patients] Zentralbl Chir. 2003;128(6): 487-92
Rosenberger C, Griethe W, Gruber G, Wiesener M, Frei U, Bachmann S, Eckardt KU: (2003) Cellular responses to hypoxia after renal segmental infarction. Kidney Int. 2003;64(3): 874-86
Griethe W, Schmitt R, Jürgensen JS, Bachmann S, Eckardt KU, Schindler R: (2003) Bone morphogenic protein-4 expression in vascular lesions of calciphylaxis. J Nephrol. 2003;16(5): 728-32
Wiesener MS, Eckardt KU: (2002) Erythropoietin, tumours and the von Hippel-Lindau gene: towards identification of mechanisms and dysfunction of oxygen sensing. Nephrol Dial Transplant. 2002;17(3): 356-9
Hörstrup JH, Gehrmann M, Schneider B, Plöger A, Froese P, Schirop T, Kampf D, Frei U, Neumann R, Eckardt KU: (2002) Elevation of serum and urine levels of TIMP-1 and tenascin in patients with renal disease. Nephrol Dial Transplant. 2002;17(6): 1005-13
Drueke TB, Eckardt KU: (2002) Role of secondary hyperparathyroidism in erythropoietin resistance of chronic renal failure patients. Nephrol Dial Transplant. 2002;17 Suppl 5(): 28-31
Eckardt KU: (2002) Anaemia of critical illness-- implications for understanding and treating rHuEPO resistance. Nephrol Dial Transplant. 2002;17 Suppl 5(): 48-55
Eckardt KU, Bittner R, Dudenhausen JW, Frei U: (2002) Post-partum 'acute renal failure'. Nephrol Dial Transplant. 2002;17(9): 1703-5
Wiesener MS, Seyfarth M, Warnecke C, Jürgensen JS, Rosenberger C, Morgan NV, Maher ER, Frei U, Eckardt KU: (2002) Paraneoplastic erythrocytosis associated with an inactivating point mutation of the von Hippel-Lindau gene in a renal cell carcinoma. Blood. 2002;99(10): 3562-5
Oppert M, Reinicke A, Müller C, Barckow D, Frei U, Eckardt KU: (2002) Elevations in procalcitonin but not C-reactive protein are associated with pneumonia after cardiopulmonary resuscitation. Resuscitation. 2002;53(2): 167-70
Rosenberger C, Mandriota S, Jürgensen JS, Wiesener MS, Hörstrup JH, Frei U, Ratcliffe PJ, Maxwell PH, Bachmann S, Eckardt KU: (2002) Expression of hypoxia-inducible factor-1alpha and -2alpha in hypoxic and ischemic rat kidneys. J Am Soc Nephrol. 2002;13(7): 1721-32
Weber G, Gross J, Kromminga A, Loew HH, Eckardt KU: (2002) Allergic skin and systemic reactions in a patient with pure red cell aplasia and anti-erythropoietin antibodies challenged with different epoetins. J Am Soc Nephrol. 2002;13(9): 2381-3
Zatyka M, da Silva NF, Clifford SC, Morris MR, Wiesener MS, Eckardt KU, Houlston RS, Richards FM, Latif F, Maher ER: (2002) Identification of cyclin D1 and other novel targets for the von Hippel-Lindau tumor suppressor gene by expression array analysis and investigation of cyclin D1 genotype as a modifier in von Hippel-Lindau disease. Cancer Res. 2002;62(13): 3803-11
Willam C, Masson N, Tian YM, Mahmood SA, Wilson MI, Bicknell R, Eckardt KU, Maxwell PH, Ratcliffe PJ, Pugh CW: (2002) Peptide blockade of HIFalpha degradation modulates cellular metabolism and angiogenesis. Proc Natl Acad Sci U S A. 2002;99(16): 10423-8
Möckel M, Scheinert D, Potapov EV, Wellnhofer E, Combé V, Nasseri BA, Maier D, Meyer S, Yankah C, Hetzer R, Frei U, Eckardt KU: (2001) Continuous measurements of renal perfusion in pigs by means of intravascular Doppler. Kidney Int. 2001;59(4): 1439-47
Eckardt KU: (2001) The CREATE trial--building the evidence. Nephrol Dial Transplant. 2001;16 Suppl 2(): 16-8
Aljama P, Bommer J, Canaud B, Carrera F, Eckardt KU, Hörl WH, Krediet RT, Locatelli F, Macdougall IC, Wikström B: (2001) Practical guidelines for the use of NESP in treating renal anaemia. Nephrol Dial Transplant. 2001;16 Suppl 3(): 22-8
Eckardt KU: (2001) After 15 years of success--perspectives of erythropoietin therapy. Nephrol Dial Transplant. 2001;16(9): 1745-9
Eckardt KU: (2001) Anaemia in end-stage renal disease: pathophysiological considerations. Nephrol Dial Transplant. 2001;16 Suppl 7(): 2-8
Wiesener MS, Münchenhagen PM, Berger I, Morgan NV, Roigas J, Schwiertz A, Jürgensen JS, Gruber G, Maxwell PH, Löning SA, Frei U, Maher ER, Gröne HJ, Eckardt KU: (2001) Constitutive activation of hypoxia-inducible genes related to overexpression of hypoxia-inducible factor-1alpha in clear cell renal carcinomas. Cancer Res. 2001;61(13): 5215-22
Eckardt KU: (2001) Target hemoglobin in patients with renal failure. Nephron. 2001;89(2): 135-43; discussion 143-4
Eckardt KU: (2001) The potential of erythropoietin and related strategies to stimulate erythropoiesis. Curr Opin Investig Drugs. 2001;2(8): 1081-5

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